UniProt ID: Q7SZE3 |
FUNCTION: Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis. {ECO:0000269|PubMed:15983403}. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. PTM: Phosphorylated. {ECO:0000269|PubMed:15983403}. DISRUPTION PHENOTYPE: In larvae, basal epidermal cells migrate to ectopic places and hyper-proliferate. {ECO:0000269|PubMed:15983403}. SIMILARITY: Belongs to the WD repeat L(2)GL family. {ECO:0000305}. |
UniProt ID: A0A8M9QMN2 |
SIMILARITY: Belongs to the WD repeat L(2)GL family. {ECO:0000256|ARBA:ARBA00008070}. |
UniProt ID: B7ZVM2 |
SIMILARITY: Belongs to the WD repeat L(2)GL family. {ECO:0000256|ARBA:ARBA00008070}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |