UniProt ID: A0A8M1PIL2 |
FUNCTION: Binds and promotes bundling of vimentin filaments originating from the Golgi. {ECO:0000256|ARBA:ARBA00002680}. FUNCTION: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. {ECO:0000256|ARBA:ARBA00025506}. PATHWAY: Amino-acid degradation; L-histidine degradation into L- glutamate; L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1. {ECO:0000256|ARBA:ARBA00005082}. SUBUNIT: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring- shaped structure. {ECO:0000256|ARBA:ARBA00025915}. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}. SIMILARITY: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family. {ECO:0000256|ARBA:ARBA00010825}. SIMILARITY: In the N-terminal section; belongs to the formiminotransferase family. {ECO:0000256|ARBA:ARBA00008297}. |
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