UniProt ID: Q7ZTY4 |
FUNCTION: Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. {ECO:0000250|UniProtKB:Q16576}. SUBUNIT: Binds directly to helix 1 of the histone fold of histone H4, a region that is not accessible when H4 is in chromatin. {ECO:0000250|UniProtKB:Q16576}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q16576}. SIMILARITY: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. {ECO:0000305}. SEQUENCE CAUTION: Sequence=AAH67546.1; Type=Frameshift; Evidence={ECO:0000305}; |
This information was provided by UniProt through a collaboration with ZFIN. (1) |