UniProt ID: Q7T2T7 |
FUNCTION: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). {ECO:0000256|PIRNR:PIRNR038006}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038006}. Note=Colocalized with methyl-CpG in the genome. {ECO:0000256|PIRNR:PIRNR038006}. |
UniProt ID: A8WIP2 |
FUNCTION: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). {ECO:0000256|PIRNR:PIRNR038006}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038006}. Note=Colocalized with methyl-CpG in the genome. {ECO:0000256|PIRNR:PIRNR038006}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |