UniProt ID: A7YT82 |
FUNCTION: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Also able to mediate N-terminal lysine myristoylation of proteins. {ECO:0000250|UniProtKB:O60551}. CATALYTIC ACTIVITY: Reaction=N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein]; Xref=Rhea:RHEA:15521, Rhea:RHEA- COMP:12666, Rhea:RHEA-COMP:12667, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57385, ChEBI:CHEBI:64723, ChEBI:CHEBI:133050; EC=2.3.1.97; Evidence={ECO:0000250|UniProtKB:O60551}; CATALYTIC ACTIVITY: Reaction=N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]; Xref=Rhea:RHEA:70671, Rhea:RHEA-COMP:17947, Rhea:RHEA-COMP:17948, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57385, ChEBI:CHEBI:189855, ChEBI:CHEBI:189856; Evidence={ECO:0000250|UniProtKB:O60551}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:70672; Evidence={ECO:0000250|UniProtKB:O60551}; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O60551}. Membrane {ECO:0000250|UniProtKB:O60551}; Peripheral membrane protein {ECO:0000250|UniProtKB:O60551}. SIMILARITY: Belongs to the NMT family. {ECO:0000255}. |
UniProt ID: H2ZRH9 |
FUNCTION: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. {ECO:0000256|RuleBase:RU000586}. CATALYTIC ACTIVITY: Reaction=N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-tetradecanoylglycyl-[protein]; Xref=Rhea:RHEA:15521, Rhea:RHEA- COMP:12666, Rhea:RHEA-COMP:12667, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287, ChEBI:CHEBI:57385, ChEBI:CHEBI:64723, ChEBI:CHEBI:133050; EC=2.3.1.97; Evidence={ECO:0000256|ARBA:ARBA00000445, ECO:0000256|RuleBase:RU000586}; SIMILARITY: Belongs to the NMT family. {ECO:0000256|ARBA:ARBA00009469, ECO:0000256|RuleBase:RU004178}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |