UniProt ID: Q7ZUQ1 |
FUNCTION: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. {ECO:0000256|RuleBase:RU367141}. CATALYTIC ACTIVITY: Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.2; Evidence={ECO:0000256|ARBA:ARBA00000249}; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670; Evidence={ECO:0000256|ARBA:ARBA00000249}; SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367141}; Lipid-anchor {ECO:0000256|RuleBase:RU367141}. Membrane {ECO:0000256|ARBA:ARBA00004423}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004423}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004423}. Midbody {ECO:0000256|ARBA:ARBA00004214}. SIMILARITY: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. {ECO:0000256|ARBA:ARBA00008112, ECO:0000256|RuleBase:RU367141}. |
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