UniProt ID: A4IGC8
CATALYTIC ACTIVITY: Reaction=ATP + L-glutamate = ADP + L-glutamyl 5-phosphate; Xref=Rhea:RHEA:14877, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:58274, ChEBI:CHEBI:456216; EC=2.7.2.11; Evidence={ECO:0000256|PIRNR:PIRNR036429};
CATALYTIC ACTIVITY: Reaction=L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH; Xref=Rhea:RHEA:19541, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474, ChEBI:CHEBI:57783, ChEBI:CHEBI:58066, ChEBI:CHEBI:58274, ChEBI:CHEBI:58349; EC=1.2.1.41; Evidence={ECO:0000256|PIRNR:PIRNR036429};
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L- glutamate 5-semialdehyde from L-glutamate: step 1/2. {ECO:0000256|PIRNR:PIRNR036429}.
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L- glutamate 5-semialdehyde from L-glutamate: step 2/2. {ECO:0000256|PIRNR:PIRNR036429}.
SIMILARITY: In the C-terminal section; belongs to the gamma- glutamyl phosphate reductase family. {ECO:0000256|PIRNR:PIRNR036429}.
SIMILARITY: In the N-terminal section; belongs to the glutamate 5- kinase family. {ECO:0000256|PIRNR:PIRNR036429}.
This information was provided by UniProt through a collaboration with ZFIN. (1)