UniProt ID: E7FFK6
FUNCTION: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. {ECO:0000256|HAMAP-Rule:MF_03137}.
CATALYTIC ACTIVITY: Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.n1; Evidence={ECO:0000256|HAMAP-Rule:MF_03137};
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000256|HAMAP-Rule:MF_03137}; Peripheral membrane protein {ECO:0000256|HAMAP-Rule:MF_03137}; Matrix side {ECO:0000256|HAMAP- Rule:MF_03137}.
SIMILARITY: Belongs to the GTP-binding elongation factor family. LepA subfamily. {ECO:0000256|HAMAP-Rule:MF_03137}.
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