UniProt ID: Q08CA5 |
FUNCTION: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. {ECO:0000256|ARBA:ARBA00003018}. PATHWAY: Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. {ECO:0000256|ARBA:ARBA00004996}. SUBUNIT: Homodimer. The active form is probably a hexamer composed of 3 homodimers. {ECO:0000256|ARBA:ARBA00026067}. SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family. {ECO:0000256|ARBA:ARBA00006478}. |
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