UniProt ID: Q6NYF2 |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane {ECO:0000256|RuleBase:RU362009}; Single-pass membrane protein {ECO:0000256|RuleBase:RU362009}. Cytoplasm {ECO:0000256|RuleBase:RU362009}. Nucleus membrane {ECO:0000256|ARBA:ARBA00004590}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004590}. DOMAIN: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion. {ECO:0000256|RuleBase:RU362009}. SIMILARITY: Belongs to the chloride channel CLIC family. {ECO:0000256|ARBA:ARBA00007655, ECO:0000256|RuleBase:RU362009}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |