UniProt ID: Q7T322 |
FUNCTION: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Regulates cell proliferation during embryonic development. May be involved in acetylating the N-terminus of mtor. {ECO:0000269|PubMed:16484612}. SUBUNIT: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of naa35, naa38 and naa30. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. DEVELOPMENTAL STAGE: Expressed at high levels at 6 hpf. Expression levels remain high through 18 hpf and 28 hpf in many developing tissues suCh as vascular structures or epidermis. By 48 hpf, expression is restricted to the head. At 5 dpf, expression is restricted to epidermis. {ECO:0000269|PubMed:16484612}. SIMILARITY: Belongs to the MAK10 family. {ECO:0000305}. CAUTION: PubMed:16484612 decribes a naa35/zEgap-containing complex as evolutionary conserved NatC complex; however, the zMak3 protein investigated in this context corresponds to mammalian NAA50 and not NAA30 and its interaction with NAA35 is ambiguous. {ECO:0000305}. |
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