UniProt ID: A3KNX5 |
FUNCTION: Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis. {ECO:0000250|UniProtKB:Q7RTU4, ECO:0000269|PubMed:22147889}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. DEVELOPMENTAL STAGE: At 60 hours post-fertilization, expressed in the mesenchyme of the fin field. {ECO:0000269|PubMed:22147889}. DISRUPTION PHENOTYPE: Morpholino knockdown of the protein causes severe truncation of pectoral fins at 72 hours post-fertilization. {ECO:0000269|PubMed:22147889}. SEQUENCE CAUTION: Sequence=AAI34058.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
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