UniProt ID: P83758 |
FUNCTION: Probable transcription factor that plays a role in configuring the spinal circuits controlling motion in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling movements. May regulate transcription (By similarity). {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070, ECO:0000269|PubMed:18282142}. TISSUE SPECIFICITY: Expressed in the developing germ cells of both gonads, mainly in spermatogonia, spermatocytes and developing oocytes. Also expressed in embryonic olfactory placode and neural tube. DEVELOPMENTAL STAGE: Expression increases gradually to a high level at pharyngula stage, which is restricted to the olfactory placode and the neural tube. In the juvenile zebrafish, the expression is first detected in undifferentiated gonad on 17 dpf. {ECO:0000269|PubMed:18282142}. SIMILARITY: Belongs to the DMRT family. {ECO:0000305}. |
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