UniProt ID: P57717 |
FUNCTION: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. SUBUNIT: Binds DNA as a homodimer. Can form a heterodimer with ER-beta (By similarity). {ECO:0000250}. SUBCELLULAR LOCATION: Nucleus. DOMAIN: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. SIMILARITY: Belongs to the nuclear hormone receptor family. NR3 subfamily. {ECO:0000305}. |
UniProt ID: A0A8M3B0Y2 |
FUNCTION: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. {ECO:0000256|ARBA:ARBA00003830, ECO:0000256|PIRNR:PIRNR002527}. SUBUNIT: Binds DNA as a homodimer. Can form a heterodimer with ER-beta. {ECO:0000256|ARBA:ARBA00026005}. SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR002527, ECO:0000256|PROSITE-ProRule:PRU00407}. SIMILARITY: Belongs to the nuclear hormone receptor family. NR3 subfamily. {ECO:0000256|ARBA:ARBA00005413, ECO:0000256|PIRNR:PIRNR002527}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |