UniProt ID: Q8JGS1 |
FUNCTION: Plays an essential role in early embryonic development (PubMed:12006978). Plays an important role in the regulation of centriole duplication (By similarity). {ECO:0000250|UniProtKB:Q15468, ECO:0000269|PubMed:12006978}. INTERACTION: Q8JGS1; E7FCY1: cenpj; NbExp=3; IntAct=EBI-15182936, EBI-15182913; SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q15468}. DISRUPTION PHENOTYPE: Embryos display defects such as small head, small eyes and dorsally bent body. {ECO:0000269|PubMed:12006978}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |