UniProt ID: Q8JHJ1
FUNCTION: Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. {ECO:0000269|PubMed:12006978, ECO:0000269|PubMed:15138505}.
FUNCTION: Component of the large ribosomal subunit. {ECO:0000250|UniProtKB:P42766}.
SUBUNIT: Component of the large ribosomal subunit. {ECO:0000250|UniProtKB:P42766}.
DISRUPTION PHENOTYPE: Embryos show various defects including an inflated hindbrain ventricle and smaller head and eyes. Mutant adults show an increased incidence of cancer, notably malignant peripheral nerve sheath tumors. {ECO:0000269|PubMed:12006978}.
SIMILARITY: Belongs to the universal ribosomal protein uL29 family. {ECO:0000305}.
This information was provided by UniProt through a collaboration with ZFIN. (1)