UniProt ID: Q9I8L5
FUNCTION: Binds hydrophobic ligands, such as cholate, in the cytoplasm. May be involved in intracellular lipid transport (By similarity). Binds one cholate per subunit. {ECO:0000250}.
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
TISSUE SPECIFICITY: Expressed in the developing embryonic liver from 48 hpf. Also expressed in the liver of 5-day-old larvae. In adults, primarily expressed in the liver, with weak expression in the testis and intestine. {ECO:0000269|PubMed:11004494, ECO:0000269|PubMed:12633865, ECO:0000269|PubMed:12815620, ECO:0000269|PubMed:16857010}.
DOMAIN: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
MISCELLANEOUS: A member of the basic liver-type FABPs, which are only found, thus far, in non-mammalian vertebrates.
SIMILARITY: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. {ECO:0000305}.
CAUTION: PubMed:12633865 reports expression in the ventral endoderm at 36 hpf, whereas PubMed:16857010 does not detect expression this early. The different timings may reflect strain- specific differences. {ECO:0000305}.
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