UniProt ID: A0A8M9PIE9 |
FUNCTION: Catalyzes the ferrous insertion into protoporphyrin IX. {ECO:0000256|ARBA:ARBA00002278, ECO:0000256|RuleBase:RU000607}. CATALYTIC ACTIVITY: Reaction=2 H(+) + heme b = Fe(2+) + protoporphyrin IX; Xref=Rhea:RHEA:22584, ChEBI:CHEBI:15378, ChEBI:CHEBI:29033, ChEBI:CHEBI:57306, ChEBI:CHEBI:60344; EC=4.98.1.1; Evidence={ECO:0000256|ARBA:ARBA00034286, ECO:0000256|RuleBase:RU000607}; PATHWAY: Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. {ECO:0000256|ARBA:ARBA00004943, ECO:0000256|RuleBase:RU000607}. SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000607}. SIMILARITY: Belongs to the ferrochelatase family. {ECO:0000256|ARBA:ARBA00007718, ECO:0000256|RuleBase:RU000607}. |
UniProt ID: Q9DFU9 |
FUNCTION: Catalyzes the ferrous insertion into protoporphyrin IX. {ECO:0000256|ARBA:ARBA00002278, ECO:0000256|RuleBase:RU000607}. CATALYTIC ACTIVITY: Reaction=2 H(+) + heme b = Fe(2+) + protoporphyrin IX; Xref=Rhea:RHEA:22584, ChEBI:CHEBI:15378, ChEBI:CHEBI:29033, ChEBI:CHEBI:57306, ChEBI:CHEBI:60344; EC=4.98.1.1; Evidence={ECO:0000256|ARBA:ARBA00034286, ECO:0000256|RuleBase:RU000607}; PATHWAY: Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. {ECO:0000256|ARBA:ARBA00004943, ECO:0000256|RuleBase:RU000607}. SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000607}. SIMILARITY: Belongs to the ferrochelatase family. {ECO:0000256|ARBA:ARBA00007718, ECO:0000256|RuleBase:RU000607}. |
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