UniProt ID: Q9I9N5 |
FUNCTION: Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd. {ECO:0000250|UniProtKB:Q15628}. SUBUNIT: Heterodimer with tnfrsf1a. {ECO:0000250|UniProtKB:Q15628}. SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q3U0V2}. Cytoplasm {ECO:0000250|UniProtKB:Q15628}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q15628}. Note=Shuttles between the cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q3U0V2}. DOMAIN: Requires the intact death domain to associate with tnfrsf1a. {ECO:0000250|UniProtKB:Q15628}. |
UniProt ID: B2GNQ4 |
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |