ZFIN ID: ZDB-TGCONSTRCT-151022-4
CITATIONS (32 total)
Transgenic Construct Name: Tg(TETRE:EGFP-kras_G12V)
Transgenic Construct Symbol: Tg(TETRE:EGFP-kras_G12V)
Morgan, K.J., Doggett, K., Geng, F., Mieruszynski, S., Whitehead, L., Smith, K.A., Hogan, B.M., Simons, C., Baillie, G.J., Molania, R., Papenfuss, A.T., Hall, T.E., Ober, E.A., Stainier, D.Y.R., Gong, Z., Heath, J.K. (2023) ahctf1 and kras mutations combine to amplify oncogenic stress and restrict liver overgrowth in a zebrafish model of hepatocellular carcinoma. eLIFE. 12:
Chen, S., Wu, J., Li, M., Sun, Q., Gong, Z., Letcher, R.J., Liu, C. (2022) A high-throughput screening assay for identification of chemicals with liver tumor promoting potential using a transgenic zebrafish line. Chemosphere. 297:134169
Lu, J.W., Lin, L.I., Sun, Y., Liu, D., Gong, Z. (2022) Effect of Lipopolysaccharides on Liver Tumor Metastasis of twist1a/krasV12 Double Transgenic Zebrafish. Biomedicines. 10(1):
Shang, Y., Zhang, H., Cheng, Y., Cao, P., Cui, J., Yin, X., Fan, S., Li, Y. (2022) Fluorescent Imaging-Guided Chemo- and Photodynamic Therapy of Hepatocellular Carcinoma with HCPT@NMOFs-RGD Nanocomposites. International Journal of Nanomedicine. 17:1381-1395
Helal, M., Yan, C., Gong, Z. (2021) Stimulation of hepatocarcinogenesis by activated cholangiocytes via Il17a/f1 pathway in kras transgenic zebrafish model. Scientific Reports. 11:1372
Zhu, Y., Yang, D., Duan, X., Zhang, Y., Chen, D., Gong, Z., Liu, C. (2021) Perfluorooctane Sulfonate Promotes Doxycycline-induced Liver Tumor Progression in Male Krasv12 Transgenic Zebrafish. Environmental research. 196:110962
Chen, S., Gong, Z., Letcher, R.J., Liu, C. (2020) Promotion effect of liver tumor progression in male kras transgenic zebrafish induced by tris (1, 3-dichloro-2-propyl) phosphate. Ecotoxicology and environmental safety. 191:110220
Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884
Xie, H., Kang, Y., Wang, S., Zheng, P., Chen, Z., Roy, S., Zhao, C. (2020) E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish. PLoS Genetics. 16:e1008655
Chen, S., Dang, Y., Gong, Z., Letcher, R.J., Liu, C. (2019) Progression of liver tumor was promoted by tris(1,3-dichloro-2-propyl) phosphate through the induction of inflammatory responses in krasV12 transgenic zebrafish. Environmental pollution (Barking, Essex : 1987). 255:113315
Fei, F., Wang, L., Sun, S., Lv, K., Yao, Y., Wang, J., Yu, M., Wang, X. (2019) Transgenic Strategies to Generate Heterogeneous Hepatic Cancer Models in Zebrafish. Journal of molecular cell biology. 11(11):1021-1023
Huo, X., Li, H., Li, Z., Yan, C., Mathavan, S., Liu, J., Gong, Z. (2019) Transcriptomic analyses of oncogenic hepatocytes reveal common and different molecular pathways of hepatocarcinogenesis in different developmental stages and genders in krasG12V transgenic zebrafish. Biochemical and Biophysical Research Communications. 510(4):558-564
Kang, Y., Xie, H., Zhao, C. (2019) Ankrd45 Is a Novel Ankyrin Repeat Protein Required for Cell Proliferation. Genes. 10(6)
Li, H., Li, Y., Lu, J.W., Huo, X., Gong, Z. (2019) Liver-specific androgen receptor knockout attenuates early liver tumor development in zebrafish. Scientific Reports. 9:10645
Li, J., Zhang, Y., Cai, C., Rong, X., Shao, M., Li, J., Yang, C., Yu, G. (2019) Collaborative assembly of doxorubicin and galactosyl diblock glycopolymers for targeted drug delivery of hepatocellular carcinoma. Biomaterials science. 8(1):189-200
Yang, Q., Salim, L., Yan, C., Gong, Z. (2019) Rapid Analysis of Effects of Environmental Toxicants on Tumorigenesis and Inflammation Using a Transgenic Zebrafish Model for Liver Cancer. Marine biotechnology (New York, N.Y.). 21(3):396-405
Yang, Q., Yan, C., Wang, X., Gong, Z. (2019) Leptin induces muscle wasting in kras-driven hepatocellular carcinoma (HCC) model in zebrafish. Disease models & mechanisms. 12(2):
Baell, J.B., Leaver, D.J., Hermans, S.J., Kelly, G.L., Brennan, M.S., Downer, N.L., Nguyen, N., Wichmann, J., McRae, H.M., Yang, Y., Cleary, B., Lagiakos, H.R., Mieruszynski, S., Pacini, G., Vanyai, H.K., Bergamasco, M.I., May, R.E., Davey, B.K., Morgan, K.J., Sealey, A.J., Wang, B., Zamudio, N., Wilcox, S., Garnham, A.L., Sheikh, B.N., Aubrey, B.J., Doggett, K., Chung, M.C., de Silva, M., Bentley, J., Pilling, P., Hattarki, M., Dolezal, O., Dennis, M.L., Falk, H., Ren, B., Charman, S.A., White, K.L., Rautela, J., Newbold, A., Hawkins, E.D., Johnstone, R.W., Huntington, N.D., Peat, T.S., Heath, J.K., Strasser, A., Parker, M.W., Smyth, G.K., Street, I.P., Monahan, B.J., Voss, A.K., Thomas, T. (2018) Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature. 560(7717):253-257
Chen, Y., Liu, W., Shang, Y., Cao, P., Cui, J., Li, Z., Yin, X., Li, Y. (2018) Folic acid-nanoscale gadolinium-porphyrin metal-organic frameworks: fluorescence and magnetic resonance dual-modality imaging and photodynamic therapy in hepatocellular carcinoma. International Journal of Nanomedicine. 14:57-74
Davis, S.P.X., Wisniewski, L., Kumar, S., Correia, T., Arridge, S.R., Frankel, P., McGinty, J., French, P.M.W. (2018) Slice-illuminated optical projection tomography. Optics letters. 43:5555-5558
Wang, J., Fei, F., Berberoglu, M.A., Sun, S., Wang, L., Dong, Z., Wang, X. (2018) Csy4-based vector system enables conditional chimeric gene editing in zebrafish without interrupting embryogenesis. Journal of molecular cell biology. 10(6):586-588
Yan, C., Yang, Q., Gong, Z. (2018) Activation of Hepatic Stellate Cells During Liver Carcinogenesis Requires Fibrinogen/Integrin αvβ5 in Zebrafish. Neoplasia (New York, N.Y.). 20:533-542
Yang, Q., Yan, C., Gong, Z. (2018) Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish. Scientific Reports. 8:8495
Yao, Y., Sun, S., Wang, J., Fei, F., Dong, Z., Ke, A.W., He, R., Wang, L., Zhang, L., Ji, M.B., Li, Q., Yu, M., Shi, G.M., Fan, J., Gong, Z., Wang, X. (2018) Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult. Cancer research. 78(19):5548-5560
Li, Y., Li, H., Spitsbergen, J.M., Gong, Z. (2017) Males develop faster and more severe hepatocellular carcinoma than females in krasV12 transgenic zebrafish.. Scientific Reports. 7:41280
Lockwood, N., Parker, J., Wilson, C., Frankel, P. (2017) Optimal Anesthetic Regime for Motionless Three-Dimensional Image Acquisition During Longitudinal Studies of Adult Nonpigmented Zebrafish. Zebrafish. 14(2):133-139
Yan, C., Yang, Q., Gong, Z. (2017) Tumor-associated neutrophils and macrophages promote gender disparity in hepatocellular carcinoma in zebrafish. Cancer research. 77(6):1395-1407
Yang, Q., Yan, C., Yin, C., Gong, Z. (2017) Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma. Cellular and molecular gastroenterology and hepatology. 3:484-499
Yao, Y., Sun, S., Fei, F., Wang, J., Wang, Y., Zhang, R., Wu, J., Liu, L., Liu, X., Cui, Z., Li, Q., Yu, M., Dang, Y., Wang, X. (2017) Screening in larval zebrafish reveals tissue-specific distributions of fifteen fluorescent compounds. Disease models & mechanisms. 10(9):1155-1164
Kumar, S., Lockwood, N., Ramel, M.C., Correia, T., Ellis, M., Alexandrov, Y., Andrews, N., Patel, R., Bugeon, L., Dallman, M.J., Brandner, S., Arridge, S., Katan, M., McGinty, J., Frankel, P., French, P.M. (2016) Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish. Oncotarget. 7(28):43939-43948
Yan, C., Huo, X., Wang, S., Feng, Y., Gong, Z. (2015) Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. Journal of hepatology. 63(2):420-8
Chew, T.W., Liu, X.J., Liu, L., Spitsbergen, J.M., Gong, Z., and Low, B.C. (2014) Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models. Oncogene. 33(21):2717-27
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