Cheung, B.B., Kleynhans, A., Mittra, R., Kim, P.Y., Holien, J.K., Nagy, Z., Ciampa, O.C., Seneviratne, J.A., Mayoh, C., Raipuria, M., Gadde, S., Massudi, H., Wong, I.P.L., Tan, O., Gong, A., Suryano, A., Diakiw, S.M., Liu, B., Arndt, G.M., Liu, T., Kumar, N., Sangfelt, O., Zhu, S., Norris, M.D., Haber, M., Carter, D.R., Parker, M.W., Marshall, G.M. (2021) A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma. Oncogene. 40(13):2367-2381

Dubiella, C., Pinch, B.J., Koikawa, K., Zaidman, D., Poon, E., Manz, T.D., Nabet, B., He, S., Resnick, E., Rogel, A., Langer, E.M., Daniel, C.J., Seo, H.S., Chen, Y., Adelmant, G., Sharifzadeh, S., Ficarro, S.B., Jamin, Y., Martins da Costa, B., Zimmerman, M.W., Lian, X., Kibe, S., Kozono, S., Doctor, Z.M., Browne, C.M., Yang, A., Stoler-Barak, L., Shah, R.B., Vangos, N.E., Geffken, E.A., Oren, R., Koide, E., Sidi, S., Shulman, Z., Wang, C., Marto, J.A., Dhe-Paganon, S., Look, T., Zhou, X.Z., Lu, K.P., Sears, R.C., Chesler, L., Gray, N.S., London, N. (2021) Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature Chemical Biology. 17(9):954-963

He, S., Mansour, M.R., Zimmerman, M.W., Ki, D.H., Layden, H.M., Akahane, K., Gjini, E., de Groh, E.D., Perez-Atayde, A.R., Zhu, S., Epstein, J.A., Look, A.T. (2016) Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. eLIFE. 5

Nunes, C., Depestel, L., Mus, L., Keller, K.M., Delhaye, L., Louwagie, A., Rishfi, M., Whale, A., Kara, N., Andrews, S.R., Dela Cruz, F., You, D., Siddiquee, A., Cologna, C.T., De Craemer, S., Dolman, E., Bartenhagen, C., De Vloed, F., Sanders, E., Eggermont, A., Bekaert, S.L., Van Loocke, W., Bek, J.W., Dewyn, G., Loontiens, S., Van Isterdael, G., Decaesteker, B., Tilleman, L., Van Nieuwerburgh, F., Vermeirssen, V., Van Neste, C., Ghesquiere, B., Goossens, S., Eyckerman, S., De Preter, K., Fischer, M., Houseley, J., Molenaar, J., De Wilde, B., Roberts, S.S., Durinck, K., Speleman, F. (2022) RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition. Science advances. 8:eabn1382

Shi, H., Tao, T., Abraham, B.J., Durbin, A.D., Zimmerman, M.W., Kadoch, C., Look, A.T. (2020) ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. Science advances. 6:eaaz3440

Tao, T., Shi, H., Mariani, L., Abraham, B.J., Durbin, A.D., Zimmerman, M.W., Powers, J.T., Missios, P., Ross, K.N., Perez-Atayde, A.R., Bulyk, M.L., Young, R.A., Daley, G.Q., Look, A.T. (2020) LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors. Proceedings of the National Academy of Sciences of the United States of America. 117(28):16516-16526

Tao, T., Sondalle, S.B., Shi, H., Zhu, S., Perez-Atayde, A.R., Peng, J., Baserga, S.J., Look, A.T. (2017) The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma. Oncogene. 36(27):3852-3867

Zhang, X., Dong, Z., Zhang, C., Ung, C.Y., He, S., Tao, T., Oliveira, A.M., Meves, A., Ji, B., Look, A.T., Li, H., Neel, B.G., Zhu, S. (2017) Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation. Cell Reports. 18:2932-2942

Zhu, S., Zhang, X., Weichert-Leahey, N., Dong, Z., Zhang, C., Lopez, G., Tao, T., He, S., Wood, A.C., Oldridge, D., Ung, C.Y., van Ree, J.H., Khan, A., Salazar, B.M., Lummertz da Rocha, E., Zimmerman, M.W., Guo, F., Cao, H., Hou, X., Weroha, S.J., Perez-Atayde, A.R., Neuberg, D.S., Meves, A., McNiven, M.A., van Deursen, J.M., Li, H., Maris, J.M., Look, A.T. (2017) LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 32(3):310-323.e5

Nunes, C., Depestel, L., Mus, L., Keller, K.M., Delhaye, L., Louwagie, A., Rishfi, M., Whale, A., Kara, N., Andrews, S.R., Dela Cruz, F., You, D., Siddiquee, A., Cologna, C.T., De Craemer, S., Dolman, E., Bartenhagen, C., De Vloed, F., Sanders, E., Eggermont, A., Bekaert, S.L., Van Loocke, W., Bek, J.W., Dewyn, G., Loontiens, S., Van Isterdael, G., Decaesteker, B., Tilleman, L., Van Nieuwerburgh, F., Vermeirssen, V., Van Neste, C., Ghesquiere, B., Goossens, S., Eyckerman, S., De Preter, K., Fischer, M., Houseley, J., Molenaar, J., De Wilde, B., Roberts, S.S., Durinck, K., Speleman, F. (2022) RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition. Science advances. 8:eabn1382

Dong, Z., Yeo, K.S., Lopez, G., Zhang, C., Dankert Eggum, E.N., Rokita, J.L., Ung, C.Y., Levee, T.M., Her, Z.P., Howe, C.J., Hou, X., van Ree, J.H., Li, S., He, S., Tao, T., Fritchie, K., Torres-Mora, J., Lehman, J.S., Meves, A., Razidlo, G.L., Rathi, K.S., Weroha, S.J., Look, A.T., van Deursen, J.M., Li, H., Westendorf, J.J., Maris, J.M., Zhu, S. (2021) GAS7 Deficiency Promotes Metastasis in MYCN-driven Neuroblastoma. Cancer research. 81(11):2995-3007

Shi, H., Tao, T., Abraham, B.J., Durbin, A.D., Zimmerman, M.W., Kadoch, C., Look, A.T. (2020) ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression. Science advances. 6:eaaz3440

Tao, T., Shi, H., Wang, M., Perez-Atayde, A.R., London, W.B., Gutierrez, A., Lemos, B., Durbin, A.D., Look, A.T. (2020) Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors. The Journal of experimental medicine. 217(10):

Zimmerman, M.W., Liu, Y., He, S., Durbin, A.D., Abraham, B.J., Easton, J., Shao, Y., Xu, B., Zhu, S., Zhang, X., Li, Z., Weichert-Leahey, N., Young, R.A., Zhang, J., Look, A.T. (2018) MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer discovery. 8:320-335

Tao, T., Sondalle, S.B., Shi, H., Zhu, S., Perez-Atayde, A.R., Peng, J., Baserga, S.J., Look, A.T. (2017) The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma. Oncogene. 36(27):3852-3867

Zhu, S., Zhang, X., Weichert-Leahey, N., Dong, Z., Zhang, C., Lopez, G., Tao, T., He, S., Wood, A.C., Oldridge, D., Ung, C.Y., van Ree, J.H., Khan, A., Salazar, B.M., Lummertz da Rocha, E., Zimmerman, M.W., Guo, F., Cao, H., Hou, X., Weroha, S.J., Perez-Atayde, A.R., Neuberg, D.S., Meves, A., McNiven, M.A., van Deursen, J.M., Li, H., Maris, J.M., Look, A.T. (2017) LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 32(3):310-323.e5

Tang, Q., Moore, J.C., Ignatius, M.S., Tenente, I.M., Hayes, M.N., Garcia, E.G., Torres Yordán, N., Bourque, C., He, S., Blackburn, J.S., Look, A.T., Houvras, Y., Langenau, D.M. (2016) Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish. Nature communications. 7:10358

Ung, C.Y., Guo, F., Zhang, X., Zhu, Z., Zhu, S. (2015) Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis. Journal of visualized experiments : JoVE. (97)