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ZFIN ID:
ZDB-GENE-990415-178
CITATIONS
(79 total)
Gene Name:
NK2 homeobox 3
Gene Symbol:
nkx2.3
Abrial, M., Paffett-Lugassy, N., Jeffrey, S., Jordan, D., O'Loughlin, E., Frederick, C.J., Burns, C.G., Burns, C.E. (2017) TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Reports. 20:973-983
Albertson, R.C., and Yelick, P.C. (2005) Roles for fgf8 signaling in left-right patterning of the visceral organs and craniofacial skeleton. Developmental Biology. 283(2):310-321
Alexander, C., Piloto, S., Le Pabic, P., Schilling, T.F. (2014) Wnt signaling interacts with bmp and edn1 to regulate dorsal-ventral patterning and growth of the craniofacial skeleton. PLoS Genetics. 10:e1004479
Anderson, M.J., Pham, V.N., Vogel, A.M., Weinstein, B.M., and Roman, B.L. (2008) Loss of unc45a precipitates arteriovenous shunting in the aortic arches. Developmental Biology. 318(2):258-267
Arnold, C.R., Lamont, R.E., Walker, J.T., Spice, P.J., Chan, C.K., Ho, C.Y., Childs, S.J. (2015) Comparative analysis of genes regulated by Dzip1/iguana and Hedgehog in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 244(2):211-23
Birkholz, D.A., Killian, E.C., George, K.M., and Artinger, K.B. (2009) Prdm1a is necessary for posterior pharyngeal arch development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(10):2575-2587
Boer, E.F., Howell, E.D., Schilling, T.F., Jette, C.A., Stewart, R.A. (2015) Fascin1-Dependent Filopodia are Required for Directional Migration of a Subset of Neural Crest Cells. PLoS Genetics. 11:e1004946
Boskovic, S., Marín-Juez, R., Jasnic, J., Reischauer, S., El Sammak, H., Kojic, A., Faulkner, G., Radojkovic, D., Stainier, D.Y.R., Kojic, S. (2018) Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLoS One. 13:e0204312
Chen, J.N. and Fishman, M.C. (1996) Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (Cambridge, England). 122(12):3809-3816
Choe, C.P., Collazo, A., Trinh, L.A., Pan, L., Moens, C.B., and Crump, J.G. (2013) Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. Developmental Cell. 24(3):296-309
Choe, C.P., Crump, J.G. (2015) Eph-Pak2a signaling regulates branching of the pharyngeal endoderm by inhibiting late-stage epithelial dynamics. Development (Cambridge, England). 142(6):1089-94
Choe, C.P., Crump, J.G. (2014) Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a. Development (Cambridge, England). 141(18):3583-93
Chuang, H.N., Cheng, H.Y., Hsiao, K.M., Lin, C.W., Lin, M.L., and Pan, H. (2010) The zebrafish homeobox gene irxl1 is required for brain and pharyngeal arch morphogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(2):639-650
Comyn, S.A., and Pilgrim, D. (2012) Lack of Developmental Redundancy between Unc45 Proteins in Zebrafish Muscle Development. PLoS One. 7(11):e48861
Culbertson, M.D., Lewis, Z.R., and Nechiporuk, A.V. (2011) Chondrogenic and Gliogenic Subpopulations of Neural Crest Play Distinct Roles during the Assembly of Epibranchial Ganglia. PLoS One. 6(9):e24443
Dalcq, J., Pasque, V., Ghaye, A., Larbuisson, A., Motte, P., Martial, J.A., and Muller, M. (2012) RUNX3, EGR1 and SOX9B Form a Regulatory Cascade Required to Modulate BMP-Signaling during Cranial Cartilage Development in Zebrafish. PLoS One. 7(11):e50140
David, N.B., Saint-Etienne, L., Tsang, M., Schilling, T.F., and Rosa, F.M. (2002) Requirement for endoderm and FGF3 in ventral head skeleton formation. Development (Cambridge, England). 129(19):4457-4468
Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
Economou, A.D., Guglielmi, L., East, P., Hill, C.S. (2022) Nodal signaling establishes a competency window for stochastic cell fate switching. Developmental Cell. 57:26042622.e52604-2622.e5
English, M.A., Lei, L., Blake, T., Wincovitch, S.M., Sood, R., Azuma, M., Hickstein, D., and Paul Liu, P. (2012) Incomplete splicing, cell division defects, and hematopoietic blockage in
dhx8
mutant zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(5):879-889
Gardner, L.D., Peck, K.A., Goetz, G.W., Linbo, T.L., Cameron, J., Scholz, N.L., Block, B.A., Incardona, J.P. (2019) Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes. The Journal of experimental biology. 222(Pt 21):
Gates, M.A., Kim, L., Egan, E.S., Cardozo, T., Sirotkin, H.I., Dougan, S.T., Lashkari, D., Abagyan, R., Schier, A.F., and Talbot, W.S. (1999) A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome research. 9(4):334-347
Hisano, Y., Ota, S., Takada, S., and Kawahara, A. (2013) Functional cooperation of spns2 and fibronectin in cardiac and lower jaw development. Biology Open. 2(8):789-794
Hong, S.K., Haldin, C.E., Lawson, N.D., Weinstein, B.M., Dawid, I.B., and Hukriede, N.A. (2005) The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney. Proceedings of the National Academy of Sciences of the United States of America. 102(51):18473-18478
Hutchinson, S.A., Tooke-Locke, E., Wang, J., Tsai, S., Katz, T., and Trede, N.S. (2012) Tbl3 regulates cell cycle length during zebrafish development. Developmental Biology. 368(2):261-272
Johnson, C.W., Hernandez-Lagunas, L., Feng, W., Melvin, V.S., Williams, T., and Artinger, K.B. (2011) Vgll2a is required for neural crest cell survival during zebrafish craniofacial development. Developmental Biology. 357(1):269-81
Keegan, B.R., Feldman, J.L., Begemann, G., Ingham, P.W., and Yelon, D. (2005) Retinoic acid signaling restricts the cardiac progenitor pool. Science (New York, N.Y.). 307(5707):247-249
Knight, R.D., Javidan, Y., Zhang, T., Nelson, S., and Schilling, T.F. (2005) AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo. Development (Cambridge, England). 132(13):3127-3138
Kopinke, D., Sasine, J., Swift, J., Stephens, W.Z., and Piotrowski, T. (2006) Retinoic acid is required for endodermal pouch morphogenesis and not for pharyngeal endoderm specification. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2695-2709
Larbuisson, A., Dalcq, J., Martial, J.A., and Muller, M. (2013) Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development. Differentiation; research in biological diversity. 86(4-5):192-206
Lee, K.H., Xu, Q., and Breitbart, R.E. (1996) A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Developmental Biology. 180(2):722-731
Li, L., Mao, A., Wang, P., Ning, G., Cao, Y., Wang, Q. (2018) Endodermal pouch-expressed
dmrt2b
is important for pharyngeal cartilage formation.. Biology Open. 7(12):
Li, L., Ning, G., Yang, S., Yan, Y., Cao, Y., Wang, Q. (2019) BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genetics. 15:e1007996
Liu, Y.H., Lin, T.C., Hwang, S.L. (2020) Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mechanisms of Development. 161:103598
Liu, Z., Ning, G., Xu, R., Cao, Y., Meng, A., Wang, Q. (2016) Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nature communications. 7:12603
Liu, Z.Z., Wang, Z.L., Choi, T.I., Huang, W.T., Wang, H.T., Han, Y.Y., Zhu, L.Y., Kim, H.T., Choi, J.H., Lee, J.S., Kim, H.G., Zhao, J., Chen, Y., Lu, Z., Tian, X.L., Pan, B.X., Li, B.M., Kim, C.H., Xu, H. (2018) Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. The American journal of pathology. 188(4):1043-1058
Lou, X., Burrows, J.T., Scott, I.C. (2015) Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest. BMC Developmental Biology. 15:41
Manoli, M., Driever, W. (2014) nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Frontiers in Neuroanatomy. 8:145
Mao, A., Zhang, M., Liu, J., Cao, Y., Wang, Q. (2019) PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis. Journal of genetics and genomics = Yi chuan xue bao. 46(12):551-559
Matsui, T., Raya, A., Kawakami, Y., Callol-Massot, C., Capdevila, J., Rodriguez-Esteban, C., Izpisúa Belmonte, J.C. (2005) Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes & Development. 19(1):164-175
Muller, I.I., Knapik, E.W., and Hatzopoulos, A.K. (2006) Expression of the protein related to Dan and Cerberus gene—prdc—During eye, pharyngeal arch, somite, and swim bladder development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2881-2888
Nishio, S.I., Gibert, Y., Bernard, L., Brunet, F., Triqueneaux, G., and Laudet, V. (2008) Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(6):1682-1690
Nissen, R.M., Yan, J., Amsterdam, A., Hopkins, N., and Burgess, S.M. (2003) Zebrafish foxi one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning. Development (Cambridge, England). 130(11):2543-2554
Okada, K., Takada, S. (2020) The second pharyngeal pouch is generated by dynamic remodeling of endodermal epithelium in zebrafish. Development (Cambridge, England). 147(24):
Olesnicky Killian, E.C., Birkholz, D.A., and Artinger, K.B. (2009) A role for chemokine signaling in neural crest cell migration and craniofacial development. Developmental Biology. 333(1):161-172
Payne-Ferreira, T.L. and Yelick, P.C. (2003) Alk8 is required for neural crest cell formation and development of pharyngeal arch cartilages. Developmental Dynamics : an official publication of the American Association of Anatomists. 228(4):683-696
Petit, D., Teppa, E., Mir, A., Vicogne, D., Thisse, C., Thisse, B., Filloux, C., Harduin-Lepers, A. (2015) Integrative view of α2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage specific losses. Mol. Biol. Evol.. 32(4):906-27
Piotrowski, T. and Nüsslein-Volhard, C. (2000) The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). Developmental Biology. 225(2):339-356
Plaster, N., Sonntag, C., Schilling, T.F., and Hammerschmidt, M. (2007) REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(7):1891-1904
Reiter, J.F., Alexander, J., Rodaway, A., Yelon, D., Patient, R., Holder, N., and Stainier, D.Y. (1999) Gata5 is required for the development of the heart and endoderm in zebrafish. Genes & Development. 13(22):2983-2995
Sperber, S.M., Saxena, V., Hatch, G., and Ekker, M. (2008) Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements. Developmental Biology. 314(1):59-70
Stafford, D. and Prince, V.E. (2002) Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Current biology : CB. 12(14):1215-1220
Stafford, D., White, R.J., Kinkel, M.D., Linville, A., Schilling, T.F., and Prince, V.E. (2006) Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells. Development (Cambridge, England). 133(5):949-956
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Suzuki, T., Hirai, Y., Uehara, T., Ohga, R., Kosaki, K., Kawahara, A. (2021) Involvement of the zebrafish trrap gene in craniofacial development. Scientific Reports. 11:24166
Thi Thu, H.N., Haw Tien, S.F., Loh, S.L., Bok Yan, J.S., and Korzh, V. (2013) tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches. PLoS One. 8(10):e77171
Trede, N.S., Medenbach, J., Damianov, A., Hung, L.H., Weber, G.J., Paw, B.H., Zhou, Y., Hersey, C., Zapata, A., Keefe, M., Barut, B.A., Stuart, A.B., Katz, T., Amemiya, C.T., Zon, L.I., and Bindereif, A. (2007) Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104(16):6608-6613
Trede, N.S., Ota, T., Kawasaki, H., Paw, B.H., Katz, T., Demarest, B., Hutchinson, S., Zhou, Y., Hersey, C., Zapata, A., Amemiya, C.T., and Zon, L.I. (2008) Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(9):2575-2584
Wallace, K.N. and Pack, M. (2003) Unique and conserved aspects of gut development in zebrafish. Developmental Biology. 255(1):12-29
Wei, S., Ning, G., Li, L., Yan, Y., Yang, S., Cao, Y., Wang, Q. (2017) A GEF activity-independent function for nuclear Net1 in Nodal/Smad2 signal transduction and mesendoderm formation. Journal of Cell Science. 130(18):3072-3082
Wotton, K.R., Weierud, F.K., Juárez-Morales, J.L., Alvares, L.E., Dietrich, S., and Lewis, K.E. (2009) Conservation of gene linkage in dispersed vertebrate NK homeobox clusters. Development genes and evolution. 219(9-10):481-496
Yamauchi, H., Goto, M., Katayama, M., Miyake, A., and Itoh, N. (2011) Fgf20b is required for the ectomesenchymal fate establishment of cranial neural crest cells in zebrafish. Biochemical and Biophysical Research Communications. 409(4):705-10
Economou, A.D., Guglielmi, L., East, P., Hill, C.S. (2022) Nodal signaling establishes a competency window for stochastic cell fate switching. Developmental Cell. 57:26042622.e52604-2622.e5
Suzuki, T., Hirai, Y., Uehara, T., Ohga, R., Kosaki, K., Kawahara, A. (2021) Involvement of the zebrafish trrap gene in craniofacial development. Scientific Reports. 11:24166
Liu, Y.H., Lin, T.C., Hwang, S.L. (2020) Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mechanisms of Development. 161:103598
Okada, K., Takada, S. (2020) The second pharyngeal pouch is generated by dynamic remodeling of endodermal epithelium in zebrafish. Development (Cambridge, England). 147(24):
Gardner, L.D., Peck, K.A., Goetz, G.W., Linbo, T.L., Cameron, J., Scholz, N.L., Block, B.A., Incardona, J.P. (2019) Cardiac remodeling in response to embryonic crude oil exposure involves unconventional NKX family members and innate immunity genes. The Journal of experimental biology. 222(Pt 21):
Li, L., Ning, G., Yang, S., Yan, Y., Cao, Y., Wang, Q. (2019) BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genetics. 15:e1007996
Mao, A., Zhang, M., Liu, J., Cao, Y., Wang, Q. (2019) PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis. Journal of genetics and genomics = Yi chuan xue bao. 46(12):551-559
Boskovic, S., Marín-Juez, R., Jasnic, J., Reischauer, S., El Sammak, H., Kojic, A., Faulkner, G., Radojkovic, D., Stainier, D.Y.R., Kojic, S. (2018) Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLoS One. 13:e0204312
Li, L., Mao, A., Wang, P., Ning, G., Cao, Y., Wang, Q. (2018) Endodermal pouch-expressed
dmrt2b
is important for pharyngeal cartilage formation.. Biology Open. 7(12):
Liu, Z.Z., Wang, Z.L., Choi, T.I., Huang, W.T., Wang, H.T., Han, Y.Y., Zhu, L.Y., Kim, H.T., Choi, J.H., Lee, J.S., Kim, H.G., Zhao, J., Chen, Y., Lu, Z., Tian, X.L., Pan, B.X., Li, B.M., Kim, C.H., Xu, H. (2018) Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. The American journal of pathology. 188(4):1043-1058
Abrial, M., Paffett-Lugassy, N., Jeffrey, S., Jordan, D., O'Loughlin, E., Frederick, C.J., Burns, C.G., Burns, C.E. (2017) TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Reports. 20:973-983
Wei, S., Ning, G., Li, L., Yan, Y., Yang, S., Cao, Y., Wang, Q. (2017) A GEF activity-independent function for nuclear Net1 in Nodal/Smad2 signal transduction and mesendoderm formation. Journal of Cell Science. 130(18):3072-3082
Liu, Z., Ning, G., Xu, R., Cao, Y., Meng, A., Wang, Q. (2016) Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nature communications. 7:12603
Arnold, C.R., Lamont, R.E., Walker, J.T., Spice, P.J., Chan, C.K., Ho, C.Y., Childs, S.J. (2015) Comparative analysis of genes regulated by Dzip1/iguana and Hedgehog in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 244(2):211-23
Boer, E.F., Howell, E.D., Schilling, T.F., Jette, C.A., Stewart, R.A. (2015) Fascin1-Dependent Filopodia are Required for Directional Migration of a Subset of Neural Crest Cells. PLoS Genetics. 11:e1004946
Choe, C.P., Crump, J.G. (2015) Eph-Pak2a signaling regulates branching of the pharyngeal endoderm by inhibiting late-stage epithelial dynamics. Development (Cambridge, England). 142(6):1089-94
Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
Lou, X., Burrows, J.T., Scott, I.C. (2015) Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest. BMC Developmental Biology. 15:41
Petit, D., Teppa, E., Mir, A., Vicogne, D., Thisse, C., Thisse, B., Filloux, C., Harduin-Lepers, A. (2015) Integrative view of α2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage specific losses. Mol. Biol. Evol.. 32(4):906-27
Alexander, C., Piloto, S., Le Pabic, P., Schilling, T.F. (2014) Wnt signaling interacts with bmp and edn1 to regulate dorsal-ventral patterning and growth of the craniofacial skeleton. PLoS Genetics. 10:e1004479
Choe, C.P., Crump, J.G. (2014) Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a. Development (Cambridge, England). 141(18):3583-93
Manoli, M., Driever, W. (2014) nkx2.1 and nkx2.4 genes function partially redundant during development of the zebrafish hypothalamus, preoptic region, and pallidum. Frontiers in Neuroanatomy. 8:145
Choe, C.P., Collazo, A., Trinh, L.A., Pan, L., Moens, C.B., and Crump, J.G. (2013) Wnt-Dependent Epithelial Transitions Drive Pharyngeal Pouch Formation. Developmental Cell. 24(3):296-309
Hisano, Y., Ota, S., Takada, S., and Kawahara, A. (2013) Functional cooperation of spns2 and fibronectin in cardiac and lower jaw development. Biology Open. 2(8):789-794
Larbuisson, A., Dalcq, J., Martial, J.A., and Muller, M. (2013) Fgf receptors Fgfr1a and Fgfr2 control the function of pharyngeal endoderm in late cranial cartilage development. Differentiation; research in biological diversity. 86(4-5):192-206
Thi Thu, H.N., Haw Tien, S.F., Loh, S.L., Bok Yan, J.S., and Korzh, V. (2013) tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches. PLoS One. 8(10):e77171
Comyn, S.A., and Pilgrim, D. (2012) Lack of Developmental Redundancy between Unc45 Proteins in Zebrafish Muscle Development. PLoS One. 7(11):e48861
Dalcq, J., Pasque, V., Ghaye, A., Larbuisson, A., Motte, P., Martial, J.A., and Muller, M. (2012) RUNX3, EGR1 and SOX9B Form a Regulatory Cascade Required to Modulate BMP-Signaling during Cranial Cartilage Development in Zebrafish. PLoS One. 7(11):e50140
English, M.A., Lei, L., Blake, T., Wincovitch, S.M., Sood, R., Azuma, M., Hickstein, D., and Paul Liu, P. (2012) Incomplete splicing, cell division defects, and hematopoietic blockage in
dhx8
mutant zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(5):879-889
Hutchinson, S.A., Tooke-Locke, E., Wang, J., Tsai, S., Katz, T., and Trede, N.S. (2012) Tbl3 regulates cell cycle length during zebrafish development. Developmental Biology. 368(2):261-272
Culbertson, M.D., Lewis, Z.R., and Nechiporuk, A.V. (2011) Chondrogenic and Gliogenic Subpopulations of Neural Crest Play Distinct Roles during the Assembly of Epibranchial Ganglia. PLoS One. 6(9):e24443
Johnson, C.W., Hernandez-Lagunas, L., Feng, W., Melvin, V.S., Williams, T., and Artinger, K.B. (2011) Vgll2a is required for neural crest cell survival during zebrafish craniofacial development. Developmental Biology. 357(1):269-81
Yamauchi, H., Goto, M., Katayama, M., Miyake, A., and Itoh, N. (2011) Fgf20b is required for the ectomesenchymal fate establishment of cranial neural crest cells in zebrafish. Biochemical and Biophysical Research Communications. 409(4):705-10
Chuang, H.N., Cheng, H.Y., Hsiao, K.M., Lin, C.W., Lin, M.L., and Pan, H. (2010) The zebrafish homeobox gene irxl1 is required for brain and pharyngeal arch morphogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(2):639-650
Birkholz, D.A., Killian, E.C., George, K.M., and Artinger, K.B. (2009) Prdm1a is necessary for posterior pharyngeal arch development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(10):2575-2587
Olesnicky Killian, E.C., Birkholz, D.A., and Artinger, K.B. (2009) A role for chemokine signaling in neural crest cell migration and craniofacial development. Developmental Biology. 333(1):161-172
Wotton, K.R., Weierud, F.K., Juárez-Morales, J.L., Alvares, L.E., Dietrich, S., and Lewis, K.E. (2009) Conservation of gene linkage in dispersed vertebrate NK homeobox clusters. Development genes and evolution. 219(9-10):481-496
Anderson, M.J., Pham, V.N., Vogel, A.M., Weinstein, B.M., and Roman, B.L. (2008) Loss of unc45a precipitates arteriovenous shunting in the aortic arches. Developmental Biology. 318(2):258-267
Nishio, S.I., Gibert, Y., Bernard, L., Brunet, F., Triqueneaux, G., and Laudet, V. (2008) Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(6):1682-1690
Sperber, S.M., Saxena, V., Hatch, G., and Ekker, M. (2008) Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements. Developmental Biology. 314(1):59-70
Trede, N.S., Ota, T., Kawasaki, H., Paw, B.H., Katz, T., Demarest, B., Hutchinson, S., Zhou, Y., Hersey, C., Zapata, A., Amemiya, C.T., and Zon, L.I. (2008) Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(9):2575-2584
Plaster, N., Sonntag, C., Schilling, T.F., and Hammerschmidt, M. (2007) REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(7):1891-1904
Trede, N.S., Medenbach, J., Damianov, A., Hung, L.H., Weber, G.J., Paw, B.H., Zhou, Y., Hersey, C., Zapata, A., Keefe, M., Barut, B.A., Stuart, A.B., Katz, T., Amemiya, C.T., Zon, L.I., and Bindereif, A. (2007) Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America. 104(16):6608-6613
Kopinke, D., Sasine, J., Swift, J., Stephens, W.Z., and Piotrowski, T. (2006) Retinoic acid is required for endodermal pouch morphogenesis and not for pharyngeal endoderm specification. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2695-2709
Muller, I.I., Knapik, E.W., and Hatzopoulos, A.K. (2006) Expression of the protein related to Dan and Cerberus gene—prdc—During eye, pharyngeal arch, somite, and swim bladder development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2881-2888
Stafford, D., White, R.J., Kinkel, M.D., Linville, A., Schilling, T.F., and Prince, V.E. (2006) Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells. Development (Cambridge, England). 133(5):949-956
Albertson, R.C., and Yelick, P.C. (2005) Roles for fgf8 signaling in left-right patterning of the visceral organs and craniofacial skeleton. Developmental Biology. 283(2):310-321
Hong, S.K., Haldin, C.E., Lawson, N.D., Weinstein, B.M., Dawid, I.B., and Hukriede, N.A. (2005) The zebrafish kohtalo/trap230 gene is required for the development of the brain, neural crest, and pronephric kidney. Proceedings of the National Academy of Sciences of the United States of America. 102(51):18473-18478
Keegan, B.R., Feldman, J.L., Begemann, G., Ingham, P.W., and Yelon, D. (2005) Retinoic acid signaling restricts the cardiac progenitor pool. Science (New York, N.Y.). 307(5707):247-249
Knight, R.D., Javidan, Y., Zhang, T., Nelson, S., and Schilling, T.F. (2005) AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo. Development (Cambridge, England). 132(13):3127-3138
Matsui, T., Raya, A., Kawakami, Y., Callol-Massot, C., Capdevila, J., Rodriguez-Esteban, C., Izpisúa Belmonte, J.C. (2005) Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. Genes & Development. 19(1):164-175
Nissen, R.M., Yan, J., Amsterdam, A., Hopkins, N., and Burgess, S.M. (2003) Zebrafish foxi one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning. Development (Cambridge, England). 130(11):2543-2554
Payne-Ferreira, T.L. and Yelick, P.C. (2003) Alk8 is required for neural crest cell formation and development of pharyngeal arch cartilages. Developmental Dynamics : an official publication of the American Association of Anatomists. 228(4):683-696
Wallace, K.N. and Pack, M. (2003) Unique and conserved aspects of gut development in zebrafish. Developmental Biology. 255(1):12-29
David, N.B., Saint-Etienne, L., Tsang, M., Schilling, T.F., and Rosa, F.M. (2002) Requirement for endoderm and FGF3 in ventral head skeleton formation. Development (Cambridge, England). 129(19):4457-4468
Stafford, D. and Prince, V.E. (2002) Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Current biology : CB. 12(14):1215-1220
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Piotrowski, T. and Nüsslein-Volhard, C. (2000) The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). Developmental Biology. 225(2):339-356
Gates, M.A., Kim, L., Egan, E.S., Cardozo, T., Sirotkin, H.I., Dougan, S.T., Lashkari, D., Abagyan, R., Schier, A.F., and Talbot, W.S. (1999) A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome research. 9(4):334-347
Reiter, J.F., Alexander, J., Rodaway, A., Yelon, D., Patient, R., Holder, N., and Stainier, D.Y. (1999) Gata5 is required for the development of the heart and endoderm in zebrafish. Genes & Development. 13(22):2983-2995
Chen, J.N. and Fishman, M.C. (1996) Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (Cambridge, England). 122(12):3809-3816
Lee, K.H., Xu, Q., and Breitbart, R.E. (1996) A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. Developmental Biology. 180(2):722-731
Additional Citations (17):
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Zebrafish Nomenclature Committee (2019) Nomenclature Data Curation (2019). Nomenclature Committee Submission.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
Zebrafish Nomenclature Committee (2019) Nomenclature Data Curation (2019). Nomenclature Committee Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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