ZFIN ID: ZDB-GENE-980528-2059
CITATIONS (500 total)
Gene Name: bone morphogenetic protein 4
Gene Symbol: bmp4
Ahuja, N., Ostwald, P., Gendernalik, A., Guzzolino, E., Pitto, L., Bark, D., Garrity, D.M. (2022) Myocardial Afterload Is a Key Biomechanical Regulator of Atrioventricular Myocyte Differentiation in Zebrafish. Journal of cardiovascular development and disease. 9(1):
El Fersioui, Y., Pinton, G., Allaman-Pillet, N., Schorderet, D.F. (2022) Premature Vertebral Mineralization in hmx1-Mutant Zebrafish. Cells. 11(7):
Halabi, R., Cechmanek, P.B., Hehr, C.L., McFarlane, S. (2022) Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development. Cell communication and signaling : CCS. 20:126
Liu, Y., Lin, Z., Peng, Y., Jiang, Y., Zhang, X., Zhu, H., Zhang, L., Chen, J., Shu, X., Luo, M., Xie, D., Chen, Y., Liao, H., Liu, M., Zhang, X., Liu, S., Wang, H., Zhou, B., Sun, H. (2022) Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome. Cell Death & Disease. 13:10541054
Ma, J., Gu, Y., Liu, J., Song, J., Zhou, T., Jiang, M., Wen, Y., Guo, X., Zhou, Z., Sha, J., He, J., Hu, Z., Luo, L., Liu, M. (2022) Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish. Cellular and molecular life sciences : CMLS. 80:1919
Mackowetzky, K., Dicipulo, R., Fox, S.C., Philibert, D.A., Todesco, H., Doshi, J.D., Kawakami, K., Tierney, K., Waskiewicz, A.J. (2022) Retinoic Acid Signaling Regulates Late Stages of Semicircular Canal Morphogenesis and Otolith Maintenance in the Zebrafish Inner Ear. Developmental Dynamics : an official publication of the American Association of Anatomists. 251(11):1798-1815
Mostofa, F., Yasid, N.A., Shamsi, S., Ahmad, S.A., Mohd-Yusoff, N.F., Abas, F., Ahmad, S. (2022) In Silico Study and Effects of BDMC33 on TNBS-Induced BMP Gene Expressions in Zebrafish Gut Inflammation-Associated Arthritis. Molecules. 27(23):
Nie, C.H., Wan, S.M., Chen, Y.L., Huysseune, A., Wu, Y.M., Zhou, J.J., Hilsdorf, A.W.S., Wang, W.M., Witten, P.E., Lin, Q., Gao, Z.X. (2022) Single-cell transcriptomes and runx2b-/- mutants reveal the genetic signatures of intermuscular bone formation in zebrafish. National science review. 9:nwac152nwac152
Rayrikar, A.Y., Wagh, G.A., Santra, M., Patra, C. (2022) Ccn2a-FGFR1-SHH signaling is necessary for intervertebral disc homeostasis and regeneration in adult zebrafish. Development (Cambridge, England). 150(1):
Wang, X., Guo, H., Yu, F., Zhang, H., Peng, Y., Wang, C., Wei, G., Yan, J. (2022) Keratin5-cytoskeleton-BMP4 network regulates cell phenotype conversions during cardiac regeneration. Experimental cell research. 418(1):113272
Wang, Y.Y., Nie, L., Xu, X.X., Shao, T., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2022) Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development. ImmunoHorizons. 6:283-298
Zhang, W., Scerbo, P., Delagrange, M., Candat, V., Mayr, V., Vriz, S., Distel, M., Ducos, B., Bensimon, D. (2022) Fgf8 dynamics and critical slowing down may account for the temperature independence of somitogenesis. Communications biology. 5:113
Anderson, E.B., Mao, Q., Ho, R.K. (2021) Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Developmental Biology. 481:201-214
Castro, J., Beviano, V., Paço, A., Leitão-Castro, J., Cadete, F., Francisco, M., Freitas, R. (2021) Hoxd13/Bmp2-mediated mechanism involved in zebrafish finfold design. Scientific Reports. 11:7165
Chen, X., Huang, Y., Gao, P., Lv, Y., Jia, D., Sun, K., Han, Y., Hu, H., Tang, Z., Ren, X., Liu, M. (2021) Knockout of mafba Causes Inner-Ear Developmental Defects in Zebrafish via the Impairment of Proliferation and Differentiation of Ionocyte Progenitor Cells. Biomedicines. 9(11):
Choe, H., Kim, M.J., Jeon, H.J., Kim, K., Kim, C., Park, J., Shin, J., Lee, S.R., Lee, S.E. (2021) Acute toxicity of the insecticide EPN upon zebrafish (Danio rerio) embryos and its related adverse effects: Verification of abnormal cardiac development and seizure-like events. Ecotoxicology and environmental safety. 222:112544
Giardoglou, P., Bournele, D., Park, M., Kanoni, S., Dedoussis, G.V., Steinberg, S.F., Deloukas, P., Beis, D. (2021) A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2. Biology Open. 10(3):
Guglielmi, L., Heliot, C., Kumar, S., Alexandrov, Y., Gori, I., Papaleonidopoulou, F., Barrington, C., East, P., Economou, A.D., French, P.M.W., McGinty, J., Hill, C.S. (2021) Smad4 controls signaling robustness and morphogenesis by differentially contributing to the Nodal and BMP pathways. Nature communications. 12:6374
Han, X., Wang, B., Jin, D., Liu, K., Wang, H., Chen, L., Zu, Y. (2021) Precise Dose of Folic Acid Supplementation Is Essential for Embryonic Heart Development in Zebrafish. Biology. 11(1):
Hoffmann, S., Roeth, R., Diebold, S., Gogel, J., Hassel, D., Just, S., Rappold, G.A. (2021) Identification and Tissue-Specific Characterization of Novel SHOX-Regulated Genes in Zebrafish Highlights SOX Family Members Among Other Genes. Frontiers in genetics. 12:688808
Jing, Y., Ren, Y., Witzel, H.R., Dobreva, G. (2021) A BMP4-p38 MAPK signaling axis controls ISL1 protein stability and activity during cardiogenesis. Stem Cell Reports. 16(8):1894-1905
Katraki-Pavlou, S., Kastana, P., Bousis, D., Ntenekou, D., Varela, A., Davos, C.H., Nikou, S., Papadaki, E., Tsigkas, G., Athanasiadis, E., Herradon, G., Mikelis, C.M., Beis, D., Papadimitriou, E. (2021) Protein tyrosine phosphatase receptor zeta 1 deletion triggers defective heart morphogenesis in mice and zebrafish. American journal of physiology. Heart and circulatory physiology. 322(1):H8-H24
Knickmeyer, M.D., Mateo, J.L., Heermann, S. (2021) BMP Signaling Interferes with Optic Chiasm Formation and Retinal Ganglion Cell Pathfinding in Zebrafish. International Journal of Molecular Sciences. 22(9):
Koopman, C.D., De Angelis, J., Iyer, S.P., Verkerk, A.O., Da Silva, J., Berecki, G., Jeanes, A., Baillie, G.J., Paterson, S., Uribe, V., Ehrlich, O.V., Robinson, S.D., Garric, L., Petrou, S., Simons, C., Vetter, I., Hogan, B.M., de Boer, T.P., Bakkers, J., Smith, K.A. (2021) The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm. Proceedings of the National Academy of Sciences of the United States of America. 118(9):
Lombó, M., Herráez, M.P. (2021) Paternal Inheritance of Bisphenol A Cardiotoxic Effects: The Implications of Sperm Epigenome. International Journal of Molecular Sciences. 22(4):
Meng, Y., Zhong, K., Chen, S., Huang, Y., Wei, Y., Wu, J., Liu, J., Xu, Z., Guo, J., Liu, F., Lu, H. (2021) Cardiac toxicity assessment of pendimethalin in zebrafish embryos. Ecotoxicology and environmental safety. 222:112514
Molagoda, I.M.N., Kang, C.H., Lee, M.H., Choi, Y.H., Lee, C.M., Lee, S., Kim, G.Y. (2021) Fisetin promotes osteoblast differentiation and osteogenesis through GSK-3β phosphorylation at Ser9 and consequent β-catenin activation, inhibiting osteoporosis. Biochemical pharmacology. 192:114676
Peng, W., Zhang, W., Wu, Q., Cai, S., Jia, T., Sun, J., Lin, Z., Alitongbieke, G., Chen, Y., Su, Y., Lin, J., Cai, L., Sun, Y., Pan, Y., Xue, Y. (2021) Agaricus bisporus-Derived Glucosamine Hydrochloride Facilitates Skeletal Injury Repair through Bmp Signaling in Zebrafish Osteoporosis Model. Journal of natural products. 84(4):1294-1305
Peng, X., Feng, G., Zhang, Y., Sun, Y. (2021) PRC1 Stabilizes Cardiac Contraction by Regulating Cardiac Sarcomere Assembly and Cardiac Conduction System Construction. International Journal of Molecular Sciences. 22(21):
Pradhan, S.J., Reddy, P.C., Smutny, M., Sharma, A., Sako, K., Oak, M.S., Shah, R., Pal, M., Deshpande, O., Dsilva, G., Tang, Y., Mishra, R., Deshpande, G., Giraldez, A.J., Sonawane, M., Heisenberg, C.P., Galande, S. (2021) Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nature communications. 12:6094
Tessadori, F., Tsingos, E., Colizzi, E.S., Kruse, F., van den Brink, S.C., van den Boogaard, M., Christoffels, V.M., Merks, R.M., Bakkers, J. (2021) Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. eLIFE. 10:
Wang, B., Rong, X., Zhou, Y., Liu, Y., Sun, J., Zhao, B., Deng, B., Lu, L., Lu, L., Li, Y., Zhou, J. (2021) Eukaryotic initiation factor 4A3 inhibits Wnt/β-catenin signaling and regulates axis formation in zebrafish embryos. Development (Cambridge, England). 148(9):
Webster, N.B., Corbet, M., Sur, A., Meyer, N.P. (2021) Role of BMP signaling during early development of the annelid Capitella teleta. Developmental Biology. 478:183-204
Yue, M.S., Martin, S.E., Martin, N.R., Taylor, M.R., Plavicki, J.S. (2021) 2,3,7,8-Tetrachlorodibenzo-p-dioxin exposure disrupts development of the visceral and ocular vasculature. Aquatic toxicology (Amsterdam, Netherlands). 234:105786
Andrés-Delgado, L., Galardi-Castilla, M., Münch, J., Peralta, M., Ernst, A., González-Rosa, J.M., Tessadori, F., Santamaría, L., Bakkers, J., Vermot, J., de la Pompa, J.L., Mercader, N. (2020) Notch and Bmp signaling pathways act coordinately during the formation of the proepicardium. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(12):1455-1469
Cang, Z., Nie, Q. (2020) Inferring spatial and signaling relationships between cells from single cell transcriptomic data. Nature communications. 11:2084
Chen, J.W., Niu, X., King, M.J., Noedl, M.T., Tabin, C.J., Galloway, J.L. (2020) The mevalonate pathway is a critical regulator of tendon cell specification. Development (Cambridge, England). 147(12):
Eckert, P., Knickmeyer, M.D., Heermann, S. (2020) In Vivo Analysis of Optic Fissure Fusion in Zebrafish: Pioneer Cells, Basal Lamina, Hyaloid Vessels, and How Fissure Fusion is Affected by BMP. International Journal of Molecular Sciences. 21(8):
Flinn, M.A., Otten, C., Brandt, Z.J., Bostrom, J.R., Kenarsary, A., Wan, T.C., Auchampach, J.A., Abdelilah-Seyfried, S., O'Meara, C.C., Link, B.A. (2020) Llgl1 regulates zebrafish cardiac development by mediating Yap stability in cardiomyocytes. Development (Cambridge, England). 147(16):
Funk, E.C., Breen, C., Sanketi, B.D., Kurpios, N., McCune, A. (2020) Changes in Nkx2.1, Sox2, Bmp4, and Bmp16 expression underlying the lung-to-gas bladder evolutionary transition in ray-finned fishes. Evolution & development. 22:384-402
Gou, D., Zhou, J., Song, Q., Wang, Z., Bai, X., Zhang, Y., Zuo, M., Wang, F., Chen, A., Yousaf, M., Yang, Z., Peng, H., Li, K., Xie, W., Tang, J., Yao, Y., Han, M., Ke, T., Chen, Q., Xu, C., Wang, Q. (2020) Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5-cryab-hspb2 signaling in zebrafish. Acta physiologica (Oxford, England). 231(3):e13567
Gu, L., Tian, L., Gao, G., Peng, S., Zhang, J., Wu, D., Huang, J., Hua, Q., Lu, T., Zhong, L., Fu, Z., Pan, X., Qian, H., Sun, L. (2020) Inhibitory effects of polystyrene microplastics on caudal fin regeneration in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 266:114664
Gu, Q., Ali, S.F., Kanungo, J. (2020) Effects of acetyl L-carnitine on zebrafish embryos: Phenotypic and gene expression studies. Journal of applied toxicology : JAT. 41(2):256-264
He, S., Li, L., Lv, L.Y., Cai, W.J., Dou, Y.Q., Li, J., Tang, S.L., Chen, X., Zhang, Z., Xu, J., Zhang, Y.P., Yin, Z., Wuertz, S., Tao, Y.X., Kuhl, H., Liang, X.F. (2020) Mandarin fish (Sinipercidae) genomes provide insights into innate predatory feeding. Communications biology. 3:361
Holowiecki, A., Linstrum, K., Ravisankar, P., Chetal, K., Salomonis, N., Waxman, J.S. (2020) Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. Development (Cambridge, England). 147(5):
Huang, Y., Chen, Z., Meng, Y., Wei, Y., Xu, Z., Ma, J., Zhong, K., Cao, Z., Liao, X., Lu, H. (2020) Famoxadone-cymoxanil induced cardiotoxicity in zebrafish embryos. Ecotoxicology and environmental safety. 205:111339
Liu, Y., Lin, Z., Liu, M., Liao, H., Chen, Y., Zhang, X., Chan, H.C., Zhou, B., Rao, L., Sun, H. (2020) CFTR deficiency causes cardiac dysplasia during zebrafish embryogenesis and is associated with dilated cardiomyopathy. Mechanisms of Development. 163:103627
Liu, Y., Lin, Z., Sun, H. (2020) Cystic fibrosis transmembrane conductance regulator (CFTR) regulates embryonic organizer formation during zebrafish early embryogenesis. The International journal of developmental biology. 64:409-413
Liu, Y., Zhu, Z., Ho, I.H.T., Shi, Y., Li, J., Wang, X., Chan, M.T.V., Cheng, C.H.K. (2020) Genetic Deletion of miR-430 Disrupts Maternal-Zygotic Transition and Embryonic Body Plan. Frontiers in genetics. 11:853
Mao, A., Zhang, M., Li, L., Liu, J., Ning, G., Cao, Y., Wang, Q. (2020) Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification. Development (Cambridge, England). 148(2):
Martini, D., Pucci, C., Gabellini, C., Pellegrino, M., Andreazzoli, M. (2020) Exposure to the natural alkaloid Berberine affects cardiovascular system morphogenesis and functionality during zebrafish development. Scientific Reports. 10:17358
Niu, X., Subramanian, A., Hwang, T.H., Schilling, T.F., Galloway, J.L. (2020) Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling. Current biology : CB. 30(17):3277-3292.e5
Peralta, M., Ortiz Lopez, L., Jerabkova, K., Lucchesi, T., Vitre, B., Han, D., Guillemot, L., Dingare, C., Sumara, I., Mercader, N., Lecaudey, V., Delaval, B., Meilhac, S.M., Vermot, J. (2020) Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis. Cell Reports. 32:107932
Rogers, K.W., ElGamacy, M., Jordan, B.M., Müller, P. (2020) Optogenetic investigation of BMP target gene expression diversity. eLIFE. 9:
Shen, Y., Lu, H., Chen, R., Zhu, L., Song, G. (2020) MicroRNA-29c affects zebrafish cardiac development via targeting Wnt4. Molecular Medicine Reports. 22:4675-4684
Vandernoot, I., Haerlingen, B., Gillotay, P., Trubiroha, A., Janssens, V., Opitz, R., Costagliola, S. (2020) Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects. Thyroid : official journal of the American Thyroid Association. 31(3):420-438
Vonica, A., Bhat, N., Phan, K., Guo, J., Iancu, L., Weber, J.A., Karger, A., Cain, J.W., Wang, E.C.E., DeStefano, G.M., O'Donnell-Luria, A.H., Christiano, A.M., Riley, B., Butler, S.J., Luria, V. (2020) Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin. Developmental Biology. 464(1):71-87
Ye, Z., Kimelman, D. (2020) hox13 genes are required for mesoderm formation and axis elongation during early zebrafish development. Development (Cambridge, England). 147(22):
Brandão, A.S., Bensimon-Brito, A., Lourenço, R., Borbinha, J., Soares, A.R., Jacinto, A. (2019) Yap induces osteoblast differentiation by modulating Bmp signalling during zebrafish caudal fin regeneration. Journal of Cell Science. 132(22):
Das, D., Jülich, D., Schwendinger-Schreck, J., Guillon, E., Lawton, A.K., Dray, N., Emonet, T., O'Hern, C.S., Shattuck, M.D., Holley, S.A. (2019) Organization of Embryonic Morphogenesis via Mechanical Information. Developmental Cell. 49(6):829-839.e5
Eckert, P., Knickmeyer, M.D., Schütz, L., Wittbrodt, J., Heermann, S. (2019) Morphogenesis and axis specification occur in parallel during optic cup and optic fissure formation, differentially modulated by BMP and Wnt. Open Biology. 9:180179
Ghersi, J.J., Mahony, C.B., Bertrand, J.Y. (2019) bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development (Cambridge, England). 146(6):
Hernandez, L., Ryckebüsch, L., Wang, C., Ling, R., Yelon, D. (2019) Tmem2 restricts atrioventricular canal differentiation by regulating degradation of hyaluronic acid. Developmental Dynamics : an official publication of the American Association of Anatomists. 248(12):1195-1210
Hoffmann, S., Paone, C., Sumer, S.A., Diebold, S., Weiss, B., Roeth, R., Clauss, S., Klier, I., Kääb, S., Schulz, A., Wild, P.S., Ghrib, A., Zeller, T., Schnabel, R.B., Just, S., Rappold, G.A. (2019) Functional Characterization of Rare Variants in the SHOX2 Gene Identified in Sinus Node Dysfunction and Atrial Fibrillation. Frontiers in genetics. 10:648
Jiang, D., Jiang, Z., Lu, D., Wang, X., Liang, H., Zhang, J., Meng, Y., Li, Y., Wu, D., Huang, Y., Chen, Y., Deng, H., Wu, Q., Xiong, J., Meng, A., Yu, L. (2019) Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation. Nature cell biology. 21:966-977
Krall, M., Htun, S., Slavotinek, A. (2019) Use of PTC124 for nonsense suppression therapy targeting BMP4 nonsense variants in vitro and the bmp4st72 allele in zebrafish. PLoS One. 14:e0212121
Lan, Y., Pan, H., Li, C., Banks, K.M., Sam, J., Ding, B., Elemento, O., Goll, M.G., Evans, T. (2019) TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis. Cell Reports. 26:720-732.e4
Li, L., Ning, G., Yang, S., Yan, Y., Cao, Y., Wang, Q. (2019) BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genetics. 15:e1007996
Liu, F., Han, X., Li, N., Liu, K., Kang, W. (2019) Aconitum alkaloids induce cardiotoxicity and apoptosis in embryonic zebrafish by influencing the expression of cardiovascular relative genes. Toxicology letters. 305:10-18
Mitra, S., Sharma, P., Kaur, S., Khursheed, M.A., Gupta, S., Chaudhary, M., Kurup, A.J., Ramachandran, R. (2019) Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration. The Journal of cell biology. 218(2):489-507
Molagoda, I.M.N., Karunarathne, W.A.H.M., Choi, Y.H., Park, E.K., Jeon, Y.J., Lee, B.J., Kang, C.H., Kim, G.Y. (2019) Fermented Oyster Extract Promotes Osteoblast Differentiation by Activating the Wnt/β-Catenin Signaling Pathway, Leading to Bone Formation. Biomolecules. 9(11):
Narboux-Neme, N., Ekker, M., Levi, G., Heude, E. (2019) Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. PLoS One. 14:e0214063
Neal, A., Nornes, S., Payne, S., Wallace, M.D., Fritzsche, M., Louphrasitthiphol, P., Wilkinson, R.N., Chouliaras, K.M., Liu, K., Plant, K., Sholapurkar, R., Ratnayaka, I., Herzog, W., Bond, G., Chico, T., Bou-Gharios, G., De Val, S. (2019) Venous identity requires BMP signalling through ALK3. Nature communications. 10:453
Rago, L., Castroviejo, N., Fazilaty, H., Garcia-Asencio, F., Ocaña, O.H., Galcerán, J., Nieto, M.A. (2019) MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates. Developmental Cell. 51:446-459.e5
Reddy, P.C., Gungi, A., Ubhe, S., Pradhan, S.J., Kolte, A., Galande, S. (2019) Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra. Communications biology. 2:434
Sarmah, S., Curtis, C., Mahin, J., Farrell, M., Engler, T.A., Sanchez-Felix, M.V., Sato, M., Ma, Y.L., Chu, S., Marrs, J.A. (2019) The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration. Biomedicines. 7(2)
Sehonova, P., Hodkovicova, N., Urbanova, M., Örn, S., Blahova, J., Svobodova, Z., Faldyna, M., Chloupek, P., Briedikova, K., Carlsson, G. (2019) Effects of antidepressants with different modes of action on early life stages of fish and amphibians. Environmental pollution (Barking, Essex : 1987). 254:112999
Wang, X., Zhou, J., Shen, M., Shen, J., Zhang, X., Jin, Y. (2019) Chlorpyrifos exposure induces lipid metabolism disorder at the physiological and transcriptomic levels in larval zebrafish. Acta biochimica et biophysica Sinica. 51(9):890-899
Xue, C., Liu, X., Wen, B., Yang, R., Gao, S., Tao, J., Zhou, J. (2019) Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c. Frontiers in cell and developmental biology. 7:277
Yan, Y., Ning, G., Li, L., Liu, J., Yang, S., Cao, Y., Wang, Q. (2019) The BMP ligand Pinhead together with Admp supports the robustness of embryonic patterning. Science advances. 5:eaau6455
Yang, R.M., Tao, J., Zhan, M., Yuan, H., Wang, H.H., Chen, S.J., Zhu, C., de Thé, H., Zhou, J., Guo, Y., Zhu, J. (2019) TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell death and differentiation. 26(11):2430-2446
Yang, Y., Dong, F., Liu, X., Xu, J., Wu, X., Zheng, Y. (2019) Flutolanil affects circadian rhythm in zebrafish (Danio rerio) by disrupting the positive regulators. Chemosphere. 228:649-655
Yang, Y., Dong, F., Liu, X., Xu, J., Wu, X., Zheng, Y. (2019) Dysregulation of circadian rhythm in zebrafish (Danio rerio) by thifluzamide: Involvement of positive and negative regulators. Chemosphere. 235:280-287
Anbalagan, S., Gordon, L., Blechman, J., Matsuoka, R.L., Rajamannar, P., Wircer, E., Biran, J., Reuveny, A., Leshkowitz, D., Stainier, D.Y.R., Levkowitz, G. (2018) Pituicyte Cues Regulate the Development of Permeable Neuro-Vascular Interfaces. Developmental Cell. 47(6):711-726.e5
Bhakta, M., Padanad, M.S., Harris, J.P., Lubczyk, C., Amatruda, J.F., Munshi, N.V. (2018) pouC regulates expression of bmp4 during atrioventricular canal formation in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 248(2):173-188
Burkhard, S.B., Bakkers, J. (2018) Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate. eLIFE. 7
Cai, C., Sang, C., Du, J., Jia, H., Tu, J., Wan, Q., Bao, B., Xie, S., Huang, Y., Li, A., Li, J., Yang, K., Wang, S., Lu, Q. (2018) Knockout of tnni1b in zebrafish causes defects in atrioventricular valve development via the inhibition of the myocardial wnt signaling pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(1):696-710
Dasgupta, S., Cheng, V., Vliet, S.M.F., Mitchell, C.A., Volz, D.C. (2018) Tris(1,3-dichloro-2-propyl) phosphate Exposure During Early-Blastula Alters the Normal Trajectory of Zebrafish Embryogenesis. Environmental science & technology. 52(18):10820-10828
Du, Z., Ma, H.L., Zhang, Z.Y., Zheng, J.W., Wang, Y.A. (2018) Transgenic Expression of A Venous Malformation Related Mutation, TIE2-R849W, Significantly Induces Multiple Malformations of Zebrafish.. International journal of medical sciences. 15:385-394
Ferese, R., Bonetti, M., Consoli, F., Guida, V., Sarkozy, A., Lepri, F.R., Versacci, P., Gambardella, S., Calcagni, G., Margiotti, K., Sparascio, F.P., Hozhabri, H., Mazza, T., Digilio, M.C., Dallapiccola, B., Tartaglia, M., Marino, B., Hertog, J.D., De Luca, A. (2018) Heterozygous missense mutations in NFATC1 are associated with atrioventricular septal defect. Human Mutation. 39(10):1428-1441
Fukui, H., Miyazaki, T., Chow, R.W., Ishikawa, H., Nakajima, H., Vermot, J., Mochizuki, N. (2018) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish. eLIFE. 7
Grassini, D.R., Lagendijk, A.K., De Angelis, J.E., Da Silva, J., Jeanes, A., Zettler, N., Bower, N.I., Hogan, B.M., Smith, K.A. (2018) Nppa and Nppb act redundantly during zebrafish cardiac development to confine AVC marker expression and reduce cardiac jelly volume. Development (Cambridge, England). 145(12)
Hsieh, F.C., Lu, Y.F., Liau, I., Chen, C.C., Cheng, C.M., Hsiao, C.D., Hwang, S.L. (2018) Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. Scientific Reports. 8:7856
Huang, M., Jiao, J., Wang, J., Xia, Z., Zhang, Y. (2018) Characterization of acrylamide-induced oxidative stress and cardiovascular toxicity in zebrafish embryos. Journal of hazardous materials. 347:451-460
Knickmeyer, M.D., Mateo, J.L., Eckert, P., Roussa, E., Rahhal, B., Zuniga, A., Krieglstein, K., Wittbrodt, J., Heermann, S. (2018) TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism. Open Biology. 8(3)
Liu, Z.Z., Wang, Z.L., Choi, T.I., Huang, W.T., Wang, H.T., Han, Y.Y., Zhu, L.Y., Kim, H.T., Choi, J.H., Lee, J.S., Kim, H.G., Zhao, J., Chen, Y., Lu, Z., Tian, X.L., Pan, B.X., Li, B.M., Kim, C.H., Xu, H. (2018) Chd7 Is Critical for Early T-Cell Development and Thymus Organogenesis in Zebrafish. The American journal of pathology. 188(4):1043-1058
Maurer, J.M., Sagerström, C.G. (2018) A parental requirement for dual-specificity phosphatase 6 in zebrafish. BMC Developmental Biology. 18:6
Murciano, C., Cazorla-Vázquez, S., Gutiérrez, J., Hijano, J.A., Ruiz-Sánchez, J., Mesa-Almagro, L., Martín-Reyes, F., Fernández, T.D., Marí-Beffa, M. (2018) Widening control of fin inter-rays in zebrafish and inferences about actinopterygian fins. Journal of anatomy. 232(5):783-805
Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, C., Schrøder, J.M., Mogensen, J.B., Blinkenkjær, L., Harder, L.M., Lundberg, E., Geimer, S., Christensen, S.T., Andersen, J.S., Larsen, L.A., Pedersen, L.B. (2018) CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium. Cell Reports. 22:2584-2592
Ramakrishnan Varadarajan, A., Mopuri, R., Streelman, J.T., McGrath, P.T. (2018) Genome-wide protein phylogenies for four African cichlid species. BMC Evolutionary Biology. 18:1
Segert, J., Schneider, I., Berger, I.M., Rottbauer, W., Just, S. (2018) Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish. Progress in Biophysics and Molecular Biology. 138:20-31
Sen, R., Pezoa, S.A., Carpio Shull, L., Hernandez-Lagunas, L., Niswander, L.A., Artinger, K.B. (2018) Kat2a and Kat2b Acetyltransferase Activity Regulates Craniofacial Cartilage and Bone Differentiation in Zebrafish and Mice. Journal of developmental biology. 6(4)
Sun, L., Gu, L., Tan, H., Liu, P., Gao, G., Tian, L., Chen, H., Lu, T., Qian, H., Fu, Z., Pan, X. (2018) Effects of 17α‑ethinylestradiol on caudal fin regeneration in zebrafish larvae. The Science of the total environment. 653:10-22
Sun, X., Chen, J., Zhang, Y., Munisha, M., Dougan, S., Sun, Y. (2018) Mga Modulates Bmpr1a Activity by Antagonizing Bs69 in Zebrafish. Frontiers in cell and developmental biology. 6:126
Swinburne, I.A., Mosaliganti, K.R., Upadhyayula, S., Liu, T.L., Hildebrand, D.G.C., Tsai, T.Y., Chen, A., Al-Obeidi, E., Fass, A.K., Malhotra, S., Engert, F., Lichtman, J.W., Kirchausen, T., Betzig, E., Megason, S.G. (2018) Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure. eLIFE. 7
Wagner, D.E., Weinreb, C., Collins, Z.M., Briggs, J.A., Megason, S.G., Klein, A.M. (2018) Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. Science (New York, N.Y.). 360(6392):981-987
Wu, Y., Zuo, Z., Chen, M., Zhou, Y., Yang, Q., Zhuang, S., Wang, C. (2018) The developmental effects of low-level procymidone towards zebrafish embryos and involved mechanism. Chemosphere. 193:928-935
Xu, P., Balczerski, B., Ciozda, A., Louie, K., Oralova, V., Huysseune, A., Crump, J.G. (2018) Fox proteins are modular competency factors for facial cartilage and tooth specification. Development (Cambridge, England). 145(12)
Yan, L., Chen, J., Zhu, X., Sun, J., Wu, X., Shen, W., Zhang, W., Tao, Q., Meng, A. (2018) Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates. Science (New York, N.Y.). 362(6417)
Yang, L.Q., Chen, M., Zhang, J.L., Ren, D.L., Hu, B. (2018) Hypoxia Delays Oligodendrocyte Progenitor Cell Migration and Myelin Formation by Suppressing Bmp2b Signaling in Larval Zebrafish. Frontiers in Cellular Neuroscience. 12:348
Zhang, L., Yang, Y., Li, B., Scott, I.C., Lou, X. (2018) The DEAD box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish. Development (Cambridge, England). 145(8)
Zhu, Y., Lin, D., Yang, D., Jia, Y., Liu, C. (2018) Environmentally relevant concentrations of the flame retardant tris(1,3-dichloro-2-propyl) phosphate change morphology of female zebrafish. Chemosphere. 212:358-364
Chen, J.R., Lai, Y.H., Tsai, J.J., Hsiao, C.D. (2017) Live Fluorescent Staining Platform for Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization. Molecules. 22(12)
Chen, L., Dong, C., Kong, S., Zhang, J., Li, X., Xu, P. (2017) Genome wide identification, phylogeny, and expression of bone morphogenetic protein genes in tetraploidized common carp (Cyprinus carpio). Gene. 627:157-163
Colombo, S., de Sena-Tomás, C., George, V., Werdich, A.A., Kapur, S., MacRae, C.A., Targoff, K.L. (2017) nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression. Development (Cambridge, England). 145(3)
Dumitrescu, E., Karunaratne, D.P., Prochaska, M.K., Liu, X., Wallace, K.N., Andreescu, S. (2017) Developmental toxicity of glycine-coated silica nanoparticles in embryonic zebrafish. Environmental pollution (Barking, Essex : 1987). 229:439-447
Duong, T.B., Ravisankar, P., Song, Y.C., Gafranek, J.T., Rydeen, A.B., Dohn, T.E., Barske, L.A., Crump, J.G., Waxman, J.S. (2017) Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Developmental Biology. 434(1):7-14
Ghosh, T.K., Aparicio-Sánchez, J.J., Buxton, S., Ketley, A., Mohamed, T., Rutland, C.S., Loughna, S., David Brook, J. (2017) Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development. Journal of Molecular and Cellular Cardiology. 114:185-198
Huang, M., Jiao, J., Wang, J., Xia, Z., Zhang, Y. (2017) Exposure to acrylamide induces cardiac developmental toxicity in zebrafish during cardiogenesis. Environmental pollution (Barking, Essex : 1987). 234:656-666
Jagadeeshan, S., Sagayaraj, R.V., Paneerselvan, N., Ghouse, S.S., Malathi, R. (2017) Toxicity and anti-angiogenicity evaluation of Pak1 inhibitor IPA-3 using zebrafish embryo model. Cell biology and toxicology. 33(1):41-56
Lu, F., Langenbacher, A., Chen, J.N. (2017) Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Developmental Biology. 421(2):139-148
Ma, J., Evrard, S., Badiola, I., Siegfried, G., Khatib, A.M. (2017) Regulation of the proprotein convertases expression and activity during regenerative angiogenesis: Role of hypoxia-inducible factor (HIF). European journal of cell biology. 96(5):457-468
Mandal, A., Holowiecki, A., Song, Y.C., Waxman, J.S. (2017) Wnt signaling balances specification of the cardiac and pharyngeal muscle fields. Mechanisms of Development. 143:32-41
Razaghi, B., Steele, S.L., Prykhozhij, S.V., Stoyek, M.R., Hill, J.A., Cooper, M.D., McDonald, L., Lin, W., Daugaard, M., Crapoulet, N., Chacko, S., Lewis, S., Scott, I.C., Sorensen, P.H.B., Berman, J.N. (2017) hace1 influences zebrafish cardiac development via ROS-dependent mechanisms. Developmental Dynamics : an official publication of the American Association of Anatomists. 247(2):289-303
Rong, X., Zhou, Y., Liu, Y., Zhao, B., Wang, B., Wang, C., Gong, X., Tang, P., Lu, L., Li, Y., Zhao, C., Zhou, J. (2017) Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos. Development (Cambridge, England). 144(9):1687-1697
Shao, M., Wang, M., Liu, Y.Y., Ge, Y.W., Zhang, Y.J., Shi, D.L. (2017) Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish.. Development (Cambridge, England). 144:3361-3374
Shi, G., Cui, Q., Pan, Y., Sheng, N., Sun, S., Guo, Y., Dai, J. (2017) 6:2 Chlorinated polyfluorinated ether sulfonate, a PFOS alternative, induces embryotoxicity and disrupts cardiac development in zebrafish embryos. Aquatic toxicology (Amsterdam, Netherlands). 185:67-75
Shih, H.Y., Hsu, S.Y., Ouyang, P., Lin, S.J., Chou, T.Y., Chiang, M.C., Cheng, Y.C. (2017) Bmp5 Regulates Neural Crest Cell Survival and Proliferation Via Two Different Signaling Pathways. Stem cells (Dayton, Ohio). 35(4):1003-1014
Su, S., Dong, Z. (2017) Comparative expression analyses of bone morphogenetic protein 4 (BMP4) expressions in muscles of tilapia and common carp indicate that BMP4 plays a role in the intermuscular bone distribution in a dose-dependent manner. Gene expression patterns : GEP. 27:106-113
Tu, H.C., Lee, G.H., Hsiao, T.H., Kao, T.T., Wang, T.Y., Tsai, J.N., Fu, T.F. (2017) One crisis, diverse impacts-Tissue-specificity of folate deficiency-induced circulation defects in zebrafish larvae. PLoS One. 12:e0188585
Venkatesan, A.M., Vyas, R., Gramann, A.K., Dresser, K., Gujja, S., Bhatnagar, S., Chhangawala, S., Gomes, C.B.F., Xi, H.S., Lian, C.G., Houvras, Y., Edwards, Y.J.K., Deng, A., Green, M., Ceol, C.J. (2017) Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. The Journal of Clinical Investigation. 128(1):294-308
Verma, A.D., Parnaik, V.K. (2017) Heart-specific expression of laminopathic mutations in transgenic zebrafish. Cell biology international. 41(7):809-819
Yue, Y., Jiang, M., He, L., Zhang, Z., Zhang, Q., Gu, C., Liu, M., Li, N., Zhao, Q. (2017) The transcription factor Foxc1a in zebrafish directly regulates expression of nkx2.5, encoding a transcriptional regulator of cardiac progenitor cells.. The Journal of biological chemistry. 293(2):638-650
Zhao, F., Shi, Y., Huang, Y., Zhan, Y., Zhou, L., Li, Y., Wan, Y., Li, H., Huang, H., Ruan, H., Luo, L., Li, L. (2017) Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 32(1):149-158
Zhou, F., Xie, F., Jin, K., Zhang, Z., Clerici, M., Gao, R., van Dinther, M., Sixma, T.K., Huang, H., Zhang, L., Ten Dijke, P. (2017) USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling. The EMBO journal. 36(11):1623-1639
Zhu, D., Fang, Y., Gao, K., Shen, J., Zhong, T.P., Li, F. (2017) Vegfa Impacts Early Myocardium Development in Zebrafish. International Journal of Molecular Sciences. 18(2)
Ahuja, S., Dogra, D., Stainier, D.Y., Reischauer, S. (2016) Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development. Developmental Biology. 412(1):71-82
Alvarado, E., Yousefelahiyeh, M., Alvarado, G., Shang, R., Whitman, T., Martinez, A., Yu, Y., Pham, A., Bhandari, A., Wang, B., Nissen, R.M. (2016) Wdr68 Mediates Dorsal and Ventral Patterning Events for Craniofacial Development. PLoS One. 11:e0166984
Barske, L., Askary, A., Zuniga, E., Balczerski, B., Bump, P., Nichols, J.T., Crump, J.G. (2016) Competition between Jagged-Notch and Endothelin1 Signaling Selectively Restricts Cartilage Formation in the Zebrafish Upper Face. PLoS Genetics. 12:e1005967
Cao, J., Navis, A., Cox, B.D., Dickson, A.L., Gemberling, M., Karra, R., Bagnat, M., Poss, K.D. (2016) Single epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration. Development (Cambridge, England). 143(2):232-43
Goi, M., Childs, S.J. (2016) Patterning Mechanisms of the Sub-Intestinal Venous Plexus in Zebrafish. Developmental Biology. 409(1):114-28
Hulsey, C.D., Fraser, G.J., Meyer, A. (2016) Biting into the Genome to Phenome Map: Developmental Genetic Modularity of Cichlid Fish Dentitions. Integrative and Comparative Biology. 56(3):373-88
Just, S., Hirth, S., Berger, I.M., Fishman, M.C., Rottbauer, W. (2016) The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation. Biochemical and Biophysical Research Communications. 477(4):581-8
Khatri, D., Zizioli, D., Tiso, N., Facchinello, N., Vezzoli, S., Gianoncelli, A., Memo, M., Monti, E., Borsani, G., Finazzi, D. (2016) Down-regulation of coasy, the gene associated with NBIA-VI, reduces Bmp signaling, perturbs dorso-ventral patterning and alters neuronal development in zebrafish. Scientific Reports. 6:37660
Kwon, H.J. (2016) Vitamin D receptor signaling is required for heart development in zebrafish embryo. Biochemical and Biophysical Research Communications. 470(3):575-8
Li, J., Yue, Y., Zhao, Q. (2016) Retinoic Acid Signaling Is Essential for Valvulogenesis by Affecting Endocardial Cushions Formation in Zebrafish Embryos. Zebrafish. 13(1):9-18
Lovely, C.B., Swartz, M.E., McCarthy, N., Norrie, J.L., Eberhart, J.K. (2016) Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England). 143(11):2000-11
Marques, C.L., Fernández, I., Viegas, M.N., Cox, C.J., Martel, P., Rosa, J., Cancela, M.L., Laizé, V. (2016) Comparative analysis of zebrafish bone morphogenetic proteins 2, 4 and 16: molecular and evolutionary perspectives. Cellular and molecular life sciences : CMLS. 73(4):841-57
Monteiro, R., Pinheiro, P., Joseph, N., Peterkin, T., Koth, J., Repapi, E., Bonkhofer, F., Kirmizitas, A., Patient, R. (2016) Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells. Developmental Cell. 38(4):358-70
Mu, X., Chai, T., Wang, K., Zhu, L., Huang, Y., Shen, G., Li, Y., Li, X., Wang, C. (2016) The developmental effect of difenoconazole on zebrafish embryos: A mechanism research. Environmental pollution (Barking, Essex : 1987). 212:18-26
Naylor, R.W., Skvarca, L.B., Thisse, C., Thisse, B., Hukriede, N.A., Davidson, A.J. (2016) BMP and retinoic acid regulate anterior-posterior patterning of the non-axial mesoderm across the dorsal-ventral axis. Nature communications. 7:12197
Perez-Camps, M., Tian, J., Chng, S.C., Sem, K.P., Sudhaharan, T., Teh, C., Wachsmuth, M., Korzh, V., Ahmed, S., Reversade, B. (2016) Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish. eLIFE. 5
Poon, K.L., Liebling, M., Kondrychyn, I., Brand, T., Korzh, V. (2016) Development of the cardiac conduction system in zebrafish. Gene expression patterns : GEP. 21(2):89-96
Powell, R., Bubenshchikova, E., Fukuyo, Y., Hsu, C., Lakiza, O., Nomura, H., Renfrew, E., Garrity, D., Obara, T. (2016) Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish. Molecular Medicine Reports. 14(3):2665-78
Sarmah, S., Muralidharan, P., Marrs, J.A. (2016) Embryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in Zebrafish. PLoS One. 11:e0161205
Uemura, M., Nagasawa, A., Terai, K. (2016) Yap/Taz transcriptional activity in endothelial cells promotes intramembranous ossification via the BMP pathway. Scientific Reports. 6:27473
Xiao, C., Gao, L., Hou, Y., Xu, C., Chang, N., Wang, F., Hu, K., He, A., Luo, Y., Wang, J., Peng, J., Tang, F., Zhu, X., Xiong, J.W. (2016) Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish. Nature communications. 7:13787
Zampedri, C., Tinoco-Cuellar, M., Carrillo-Rosas, S., Diaz-Tellez, A., Ramos-Balderas, J.L., Pelegri, F., Maldonado, E. (2016) Zebrafish P54 RNA helicases are cytoplasmic granule residents that are required for development and stress resilience. Biology Open. 5(10):1473-1484
Askary, A., Mork, L., Paul, S., He, X., Izuhara, A.K., Gopalakrishnan, S., Ichida, J.K., McMahon, A.P., Dabizljevic, S., Dale, R., Mariani, F.V., Crump, J.G. (2015) Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Developmental Cell. 35:358-65
Dina, C., Bouatia-Naji, N., Tucker, N., Delling, F.N., Toomer, K., Durst, R., Perrocheau, M., Fernandez-Friera, L., Solis, J., PROMESA investigators, Le Tourneau, T., Chen, M.H., Probst, V., Bosse, Y., Pibarot, P., Zelenika, D., Lathrop, M., Hercberg, S., Roussel, R., Benjamin, E.J., Bonnet, F., Lo, S.H., Dolmatova, E., Simonet, F., Lecointe, S., Kyndt, F., Redon, R., Le Marec, H., Froguel, P., Ellinor, P.T., Vasan, R.S., Bruneval, P., Markwald, R.R., Norris, R.A., Milan, D.J., Slaugenhaupt, S.A., Levine, R.A., Schott, J.J., Hagege, A.A., Mvp-France, Jeunemaitre, X., Leducq Transatlantic MITRAL Network (2015) Genetic association analyses highlight biological pathways underlying mitral valve prolapse. Nature Genetics. 47(10):1206-11
Durst, R., Sauls, K., Peal, D.S., deVlaming, A., Toomer, K., Leyne, M., Salani, M., Talkowski, M.E., Brand, H., Perrocheau, M., Simpson, C., Jett, C., Stone, M.R., Charles, F., Chiang, C., Lynch, S.N., Bouatia-Naji, N., Delling, F.N., Freed, L.A., Tribouilloy, C., Le Tourneau, T., LeMarec, H., Fernandez-Friera, L., Solis, J., Trujillano, D., Ossowski, S., Estivill, X., Dina, C., Bruneval, P., Chester, A., Schott, J.J., Irvine, K.D., Mao, Y., Wessels, A., Motiwala, T., Puceat, M., Tsukasaki, Y., Menick, D.R., Kasiganesan, H., Nie, X., Broome, A.M., Williams, K., Johnson, A., Markwald, R.R., Jeunemaitre, X., Hagege, A., Levine, R.A., Milan, D.J., Norris, R.A., Slaugenhaupt, S.A. (2015) Mutations in DCHS1 cause mitral valve prolapse. Nature. 525(7567):109-13
Ear, J., Huang, H., Wilson, T., Tehrani, Z., Lindgren, A., Sung, V., Laadem, A., Daniel, T.O., Chopra, R., Lin, S. (2015) RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood. 126(7):880-90
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
Gu, W., Monteiro, R., Zuo, J., Simões, F.C., Martella, A., Andrieu-Soler, C., Grosveld, F., Sauka-Spengler, T., Patient, R. (2015) A Novel TGFβ Modulator that Uncouples R-Smad/I-Smad-Mediated Negative Feedback from R-Smad/Ligand-Driven Positive Feedback. PLoS Biology. 13:e1002051
Heermann, S., Schütz, L., Lemke, S., Krieglstein, K., Wittbrodt, J. (2015) Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein. eLIFE. 4
Kantarci, H., Edlund, R.K., Groves, A.K., Riley, B.B. (2015) Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling. PLoS Genetics. 11:e1005037
Kenyon, E.J., Campos, I., Bull, J.C., Williams, P.H., Stemple, D.L., Clark, M.D. (2015) Zebrafish Rab5 Proteins and a role for Rab5ab in nodal signalling. Developmental Biology. 397(2):212-24
Lin, K.Y., Kao, S.H., Lai, C.M., Chen, C.T., Wu, C.Y., Hsu, H.J., Wang, W.D. (2015) Tumor Suppressor Lzap Suppresses Wnt/β-catenin signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of GSK3. The Journal of biological chemistry. 290(50):29808-19
Ma, W.R., Zhang, J. (2015) Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tissue separation and preventing posterior cell death. Development (Cambridge, England). 142(4):763-73
Merkes, C., Turkalo, T.K., Wilder, N., Park, H., Wenger, L.W., Lewin, S.J., Azuma, M. (2015) Ewing Sarcoma Ewsa Protein Regulates Chondrogenesis of Meckel's Cartilage through Modulation of Sox9 in Zebrafish. PLoS One. 10:e0116627
Palencia-Desai, S., Rost, M.S., Schumacher, J.A., Ton, Q.V., Craig, M.P., Baltrunaite, K., Koenig, A.L., Wang, J., Poss, K.D., Chi, N.C., Stainier, D.Y., Sumanas, S. (2015) Myocardium and BMP signaling are required for endocardial differentiation. Development (Cambridge, England). 142(13):2304-15
Satija, R., Farrell, J.A., Gennert, D., Schier, A.F., Regev, A. (2015) Spatial reconstruction of single-cell gene expression data. Nat. Biotechnol.. 33(5):495-502
Wang, Y., Li, W.H., Li, Z., Liu, W., Zhou, L., Gui, J.F. (2015) BMP and RA signaling cooperate to regulate Apolipoprotein C1 expression during embryonic development. Gene. 554:196-204
Wu, D., Mandal, S., Choi, A., Anderson, A., Prochazkova, M., Perry, H., Gil-da-Silva-Lopes, V.L., Lao, R., Wan, E., Tang, P.L., Kwok, P.Y., Klein, O., Zhuan, B., Slavotinek, A.M. (2015) DLX4 is Associated With Orofacial Clefting and Abnormal Jaw Development. Human molecular genetics. 24(15):4340-52
Yang, R., Yan, S., Zhu, X., Li, C.Y., Liu, Z., Xiong, J.W. (2015) Antimalarial drug artemisinin depletes erythrocytes by activating apoptotic pathways in zebrafish. Experimental hematology. 43(4):331-341.e8
Yang, X., Gu, Q., Lin, L., Li, S., Zhong, S., Li, Q., Cui, Z. (2015) Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish. Molecular and cellular biology. 35(7):1110-24
Zhang, Y., Wang, H., Zhang, J., Zheng, F., Jiang, N., Ma, D. (2015) Tissue factor pathway inhibitor-2 is critical in zebrafish cardiogenesis. Biochemical and Biophysical Research Communications. 456(3):827-33
Zhu, W., Yao, X., Liang, Y., Liang, D., Song, L., Jing, N., Li, J., Wang, G. (2015) Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling. Development (Cambridge, England). 142(3):465-76
Bu, Y., Su, F., Wang, X., Gao, H., Lei, L., Chang, N., Wu, Q., Hu, K., Zhu, X., Chang, Z., Meng, K., Xiong, J.W. (2014) Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. Journal of Cell Science. 127(Pt 12):2761-70
Chang, W.N., Lee, G.H., Kao, T.T., Lin, C.Y., Hsiao, T.H., Tsai, J.N., Chen, B.H., Chen, Y.H., Wu, H.R., Tsai, H.J., Fu, T.F. (2014) Knocking down 10-formyltetrahydrofolate dehydrogenase increased oxidative stress and impeded zebrafish embryogenesis by obstructing morphogenetic movement. Biochimica et biophysica acta. General subjects. 1840(7):2340-2350
Chang-Chien, J., Yen, Y.C., Chien, K.H., Li, S.Y., Hsu, T.C., Yang, J.J. (2014) The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear. Hearing Research. 313:55-66
Dickover, M., Hegarty, J.M., Ly, K., Lopez, D., Yang, H., Zhang, R., Tedeschi, N., Hsiai, T.K., Chi, N.C. (2014) The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Developmental Biology. 389:182-91
Dietrich, A.C., Lombardo, V.A., Abdelilah-Seyfried, S. (2014) Blood Flow and Bmp Signaling Control Endocardial Chamber Morphogenesis. Developmental Cell. 30:367-377
Du, T.T., Xu, P.F., Dong, Z.W., Fan, H.B., Jin, Y., Dong, M., Chen, Y., Pan, W.J., Ren, R.B., Liu, T.X., Deng, M., Huang, Q.H. (2014) Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1. Developmental Biology. 392(2):233-44
Heude, E., Shaikho, S., Ekker, M. (2014) The dlx5a/dlx6a Genes Play Essential Roles in the Early Development of Zebrafish Median Fin and Pectoral Structures. PLoS One. 9:e98505
Holly, V.L., Widen, S.A., Famulski, J.K., and Waskiewicz, A.J. (2014) Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development. Developmental Biology. 388(2):192-204
Junker, J.P., Noël, E.S., Guryev, V., Peterson, K.A., Shah, G., Huisken, J., McMahon, A.P., Berezikov, E., Bakkers, J., van Oudenaarden, A. (2014) Genome-wide RNA Tomography in the Zebrafish Embryo. Cell. 159:662-75
Kelly, M.L., Astsaturov, A., Rhodes, J., Chernoff, J. (2014) A Pak1/Erk Signaling Module Acts through Gata6 to Regulate Cardiovascular Development in Zebrafish. Developmental Cell. 29:350-9
Kim, J.D., Kim, H.J., Koun, S., Ham, H.J., Kim, M.J., Rhee, M., Huh, T.L. (2014) Zebrafish Crip2 Plays a Critical Role in Atrioventricular Valve Development by Downregulating the Expression of ECM Genes in the Endocardial Cushion. Molecules and cells. 37(5):406-11
Kizil, C., Küchler, B., Yan, J.J., Özhan, G., Moro, E., Argenton, F., Brand, M., Weidinger, G., Antos, C.L. (2014) Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization. Development (Cambridge, England). 141:3529-39
Kujawski, S., Lin, W., Kitte, F., Börmel, M., Fuchs, S., Arulmozhivarman, G., Vogt, S., Theil, D., Zhang, Y., Antos, C.L. (2014) Calcineurin regulates coordinated outgrowth of zebrafish regenerating fins. Developmental Cell. 28:573-87
Lee, E., Koo, Y., Ng, A., Wei, Y., Luby-Phelps, K., Juraszek, A., Xavier, R.J., Cleaver, O., Levine, B., and Amatruda, J.F. (2014) Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 10(4):572-87
Li, J., Jia, W., Zhao, Q. (2014) Excessive nitrite affects zebrafish valvulogenesis through yielding too much NO signaling. PLoS One. 9:e92728
Li, M., Hu, X., Zhu, J., Zhu, C., Zhu, S., Liu, X., Xu, J., Han, S., Yu, Z. (2014) Overexpression of miR-19b Impairs Cardiac Development in Zebrafish by Targeting ctnnb1. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 33:1988-2002
Mommaerts, H., Esguerra, C.V., Hartmann, U., Luyten, F.P., Tylzanowski, P. (2014) Smoc2 modulates embryonic myelopoiesis during zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(11):1375-90
Philipp, M., Berger, I.M., Just, S., Caron, M.G. (2014) Overlapping and Opposing Functions of GRK2 and GRK5 during Heart Development. The Journal of biological chemistry. 289(38):26119-30
Pouget, C., Peterkin, T., Simões, F.C., Lee, Y., Traver, D., Patient, R. (2014) FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nature communications. 5:5588
Shin, S.H., Lee, S., Bae, J.S., Jee, J.G., Cha, H.J., Lee, Y.M. (2014) Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos. Molecules and cells. 37:330-6
Stewart, S., Gomez, A.W., Armstrong, B.E., Henner, A., and Stankunas, K. (2014) Sequential and opposing activities of Wnt and BMP coordinate zebrafish bone regeneration. Cell Reports. 6(3):482-498
Tang, C.H., Lai, Y.R., Chen, Y.C., Li, C.H., Lu, Y.F., Chen, H.Y., Lien, H.W., Yang, C.H., Huang, C.J., Wang, C.Y., Kao, C.F., Hwang, S.P. (2014) Expression of zebrafish anterior gradient 2 in the semicircular canals and supporting cells of otic vesicle sensory patches is regulated by Sox10. Biochimica et biophysica acta. Gene regulatory mechanisms. 1839(6):425-37
Tong, X., Zu, Y., Li, Z., Li, W., Ying, L., Yang, J., Wang, X., He, S., Liu, D., Zhu, Z., Chen, J., Lin, S., and Zhang, B. (2014) Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nature communications. 5:3153
Venturin, M., Carra, S., Gaudenzi, G., Brunelli, S., Gallo, G.R., Moncini, S., Cotelli, F., Riva, P. (2014) ADAP2 in heart development: a candidate gene for the occurrence of cardiovascular malformations in NF1 microdeletion syndrome. Journal of Medical Genetics. 51(7):436-43
Wehner, D., Cizelsky, W., Vasudevaro, M.D., Özhan, G., Haase, C., Kagermeier-Schenk, B., Röder, A., Dorsky, R.I., Moro, E., Argenton, F., Kühl, M., and Weidinger, G. (2014) Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin. Cell Reports. 6(3):467-481
Wei, C.Y., Wang, H.P., Zhu, Z.Y., and Sun, Y.H. (2014) Transcriptional factors Smad1 and Smad9 act redundantly to mediate zebrafish ventral specification downstream of Smad5. The Journal of biological chemistry. 289(10):6604-18
Xu, P.F., Houssin, N., Ferri-Lagneau, K.F., Thisse, B., Thisse, C. (2014) Construction of a vertebrate embryo from two opposing morphogen gradients. Science (New York, N.Y.). 344:87-9
Xue, Y., Zheng, X., Huang, L., Xu, P., Ma, Y., Min, Z., Tao, Q., Tao, Y., Meng, A. (2014) Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development. Nature communications. 5:3766
Yao, D., Zhao, F., Wu, Y., Wang, J., Wei, D., Zhao, J., Zhu, Z., Liu, D. (2014) Dissecting the differentiation process of the pre-placodal ectoderm in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(10):1338-51
Banjo, T., Grajcarek, J., Yoshino, D., Osada, H., Miyasaka, K.Y., Kida, Y.S., Ueki, Y., Nagayama, K., Kawakami, K., Matsumoto, T., Sato, M., and Ogura, T. (2013) Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature communications. 4:1978
Burkhalter, M.D., Fralish, G.B., Premont, R.T., Caron, M.G., and Philipp, M. (2013) Grk5l Controls Heart Development by Limiting mTOR Signaling during Symmetry Breaking. Cell Reports. 4(4):625-632
Chen, I.H., Wang, H.H., Hsieh, Y.S., Huang, W.C., Yeh, H.I., and Chuang, Y.J. (2013) PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish. Cardiovascular research. 97(3):443-453
Choudhry, P., and Trede, N.S. (2013) DiGeorge Syndrome Gene tbx1 Functions through wnt11r to Regulate Heart Looping and Differentiation. PLoS One. 8(3):e58145
Geng, F.S., Abbas, L., Baxendale, S., Holdsworth, C.J., Swanson, A.G., Slanchev, K., Hammerschmidt, M., Topczewski, J., and Whitfield, T.T. (2013) Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene. Development (Cambridge, England). 40(21):4362-4374
Khodiyar, V.K., Howe, D., Talmud, P.J., Breckenridge, R., Lovering, R.C. (2013) From zebrafish heart jogging genes to mouse and human orthologs: using Gene Ontology to investigate mammalian heart development.. F1000 Research. 2:1-17
Kolpa, H.J., Peal, D.S., Lynch, S.N., Giokas, A.C., Ghatak, S., Misra, S., Norris, R.A., MacRae, C.A., Markwald, R.R., Ellinor, P., Bischoff, J., and Milan, D.J. (2013) miR-21 represses Pdcd4 during cardiac valvulogenesis. Development (Cambridge, England). 140(10):2172-80
Lenhart, K.F., Holtzman, N.G., Williams, J.R., and Burdine, R.D. (2013) Integration of Nodal and BMP Signals in the Heart Requires FoxH1 to Create Left-Right Differences in Cell Migration Rates That Direct Cardiac Asymmetry. PLoS Genetics. 9(1):e1003109
Li, C.W., and Ge, W. (2013) Regulation of the Activin-Inhibin-Follistatin System by Bone Morphogenetic Proteins in the Zebrafish Ovary. Biology of reproduction. 89(3):55
Lin, C.Y., Lee, H.C., Chen, H.C., Hsieh, C.C., and Tsai, H.J. (2013) Normal Function of Myf5 During Gastrulation Is Required for Pharyngeal Arch Cartilage Development in Zebrafish Embryos. Zebrafish. 10(4):486-99
Liu, X., Xiong, C., Jia, S., Zhang, Y., Chen, Y.G., Wang, Q., and Meng, A. (2013) Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region. Nature communications. 4:1728
Monte, E., Mouillesseaux, K., Chen, H., Kimball, T., Ren, S., Wang, Y., Chen, J.N., Vondriska, T.M., and Franklin, S. (2013) Systems Proteomics of Cardiac Chromatin Identifies Nucleolin as a Regulator of Growth and Cellular Plasticity in Cardiomyocytes. American journal of physiology. Heart and circulatory physiology. 305(11):H1624-38
Ning, G., Liu, X., Dai, M., Meng, A., and Wang, Q. (2013) MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation. Developmental Cell. 24(3):283-295
Noël, E.S., Verhoeven, M., Lagendijk, A.K., Tessadori, F., Smith, K., Choorapoikayil, S., den Hertog, J., and Bakkers, J. (2013) A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nature communications. 4:2754
Parrie, L.E., Renfrew, E.M., Vander Wal, A., Mueller, R.L., and Garrity, D.M. (2013) Zebrafish tbx5 paralogs demonstrate independent essential requirements in cardiac and pectoral fin development. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(5):485-502
Ramel, M.C., and Hill, C.S. (2013) The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands. Developmental Biology. 378(2):170-82
Samson, S.C., Ferrer, T., Jou, C.J., Sachse, F.B., Shankaran, S.S., Shaw, R.M., Chi, N.C., Tristani-Firouzi, M., and Yost, H.J. (2013) 3-OST-7 regulates BMP-dependent cardiac contraction. PLoS Biology. 11(12):e1001727
Sarmah, S., and Marrs, J.A. (2013) Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: Prevention with folic acid. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(10):1184-201
Tsao, K.C., Tu, C.F., Lee, S.J., and Yang, R.B. (2013) Zebrafish scube1 [signal peptide-CUB (complement protein C1r/C1s, Uegf, and Bmp1)-EGF domain-containing protein 1] Is Involved in Primitive Hematopoiesis. The Journal of biological chemistry. 288(7):5017-5026
Tse, W.K., Jiang, Y.J., and Wong, C.K. (2013) Zebrafish transforming growth factor-beta-stimulated clone 22 domain 3 (TSC22D3) plays critical roles in Bmp-dependent dorsoventral patterning via 2 deubiquitinating enzymes Usp15 and Otud4. Biochimica et biophysica acta. General subjects. 1830(10):4584-93
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Veerkamp, J., Rudolph, F., Cseresnyes, Z., Priller, F., Otten, C., Renz, M., Schaefer, L., and Abdelilah-Seyfried, S. (2013) Unilateral dampening of bmp activity by nodal generates cardiac left-right asymmetry. Developmental Cell. 24(6):660-667
Wang, L., Liu, T., Xu, L., Gao, Y., Wei, Y., Duan, C., Chen, G.Q., Lin, S., Patient, R., Zhang, B., Hong, D., and Liu, F. (2013) Fev regulates hematopoietic stem cell development via ERK signaling. Blood. 122(3):367-75
Wang, X., Yu, Q., Wu, Q., Bu, Y., Changm, N.N., Yan, S., Zhou, X.H., Zhu, X., and Xiong, J.W. (2013) Genetic Interaction between pku300 and fbn2b Controls Endocardial Cell Proliferation and Valve Development in Zebrafish. Journal of Cell Science. 126(Pt 6):1381-91
Warga, R.M., Mueller, R.L., Ho, R.K., and Kane, D.A. (2013) Zebrafish Tbx16 regulates intermediate mesoderm cell fate by attenuating Fgf activity. Developmental Biology. 383(1):75-89
Wong, T.T., and Collodi, P. (2013) Effects of specific and prolonged expression of zebrafish growth factors, Fgf2 and Lif in primordial germ cells in vivo. Biochemical and Biophysical Research Communications. 430(1):347-351
Wong, T.T., and Collodi, P. (2013) Dorsomorphin promotes survival and germline competence of zebrafish spermatogonial stem cells in culture. PLoS One. 8(8):e71332
Wu, T.S., Yang, J.J., Yu, F.Y., and Liu, B.H. (2013) Cardiotoxicity of mycotoxin citrinin and involvement of microRNA-138 in zebrafish embryos. Toxicological sciences : an official journal of the Society of Toxicology. 136(2):402-12
Xie, H., Fan, X., Tang, X., Wan, Y., Chen, F., Wang, X., Wang, Y., Li, Y., Tang, M., Liu, D., Jiang, Z., Liu, X., Yuan, W., Li, G., Ye, X., Zhou, J., Deng, Y., and Wu, X. (2013) The LIM protein fhlA is essential for heart chamber development in zebrafish embryos. Current Molecular Medicine. 13(6):979-92
Balczerski, B., Matsutani, M., Castillo, P., Osborne, N., Stainier, D.Y., and Crump, J.G. (2012) Analysis of Sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. Developmental Biology. 361(2):230-241
Chernyavskaya, Y., Ebert, A.M., Milligan, E., and Garrity, D.M. (2012) The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(4):648-662
Das, A., and Crump, J.G. (2012) Bmps and id2a act upstream of twist1 to restrict ectomesenchyme potential of the cranial neural crest. PLoS Genetics. 8(5):e1002710
Ferri-Lagneau, K.F., Moshal, K.S., Grimes, M., Zahora, B., Lv, L., Sang, S., and Leung, T. (2012) Ginger Stimulates Hematopoiesis via Bmp Pathway in Zebrafish. PLoS One. 7(6):e39327
Flowers, G.P., Topczewska, J.M., and Topczewski, J. (2012) A zebrafish Notum homolog specifically blocks the Wnt/beta-catenin signaling pathway. Development (Cambridge, England). 139(13):2416-2425
Garnaas, M.K., Cutting, C.C., Meyers, A., Kelsey, P.B., Harris, J.M., North, T.E., and Goessling, W. (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Developmental Biology. 372(2):178-189
Glenn, N.O., McKane, M., Kohli, V., Wen, K.K., Rubenstein, P.A., Bartmanm, T., and Sumanas, S. (2012) The W-Loop of Alpha-Cardiac Actin Is Critical for Heart Function and Endocardial Cushion Morphogenesis in Zebrafish. Molecular and cellular biology. 32(17):3527-3540
Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M. (2012) Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Developmental Biology. 369(2):199-210
Huang, H., Jin, T., He, J., Ding, Q., Xu, D., Wang, L., Zhang, Y., Pan, Y., Wang, Z., and Chen, Y. (2012) Progesterone and AdipoQ Receptor 11 Links Ras Signaling to Cardiac Development in Zebrafish. Arterioscler. Thromb. Vasc. Biol.. 32(9):2158-2170
Kim, G.Y., Kim, H.Y., Kim, H.T., Moon, J.M., Kim, C.H., Kang, S., and Rhim, H. (2012) HtrA1 Is a Novel Antagonist Controlling Fibroblast Growth Factor (FGF) Signaling via Cleavage of FGF8. Molecular and cellular biology. 32(21):4482-4492
Kim, Y.S., Kim, M.J., Koo, T.H., Kim, J.D., Koun, S., Ham, H.J., Lee, Y.M., Rhee, M., Yeo, S.Y., and Huh, T.L. (2012) Histone deacetylase is required for the activation of Wnt/β-catenin signaling crucial for heart valve formation in zebrafish embryos. Biochemical and Biophysical Research Communications. 423(1):140-146
Kirchmaier, B.C., Poon, K.L., Schwerte, T., Huisken, J., Winkler, C., Jungblut, B., Stainier, D.Y., and Brand, T. (2012) The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development. Developmental Biology. 363(2):438-450
Kruse-Bend, R., Rosenthal, J., Quist, T.S., Veien, E.S., Fuhrmann, S., Dorsky, R.I., and Chien, C.B. (2012) Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish. Developmental Biology. 371(1):57-65
Li, C.W., Zhou, R., and Ge, W. (2012) Differential regulation of gonadotropin receptors by bone morphogenetic proteins in the zebrafish ovary. General and comparative endocrinology. 176(3):420-425
Li, X., Ma, Y., Li, D., Gao, X., Li, P., Bai, N., Luo, M., Tan, X., Lu, C.L., and Ma, X. (2012) Arsenic Impairs Embryo Development via Down-regulating Dvr1 Expression in Zebrafish. Toxicology letters. 212(2):161-168
Lou, Q., He, J., Hu, L., and Yin, Z. (2012) Role of lbx2 in the noncanonical Wnt signaling pathway for convergence and extension movements and hypaxial myogenesis in zebrafish. Biochimica et biophysica acta. Molecular cell research. 1823(5):1024-1032
Moriarty, M.A., Ryan, R., Lalor, P., Dockery, P., Byrnes, L., and Grealy, M. (2012) Loss of plakophilin 2 disrupts heart development in zebrafish. The International journal of developmental biology. 56(9):711-718
Nesan, D., Kamkar, M., Burrows, J., Scott, I.C., Marsden, M., Vijayan, M.M. (2012) Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish. Endocrinology. 153(3):1288-1300
Poon, K.L., Tan, K.T., Wei, Y.Y., Ng, C.P., Colman, A., Korzh, V., and Xu, X.Q. (2012) RNA-binding protein RBM24 is required for sarcomere assembly and heart contractility. Cardiovascular research. 94(3):418-427
Schuff, M., Siegel, D., Philipp, M., Bundschu,. K., Heymann, N., Donow, C., and Knöchel, W. (2012) Characterization of Danio rerio Nanog and Functional Comparison to Xenopus Vents. Stem cells and development. 21(8):1225-1238
Tessadori, F., van Weerd, J.H., Burkhard, S.B., Verkerk, A.O., de Pater, E., Boukens, B.J., Vink, A., Christoffels, V.M., and Bakkers, J. (2012) Identification and functional characterization of cardiac pacemaker cells in zebrafish. PLoS One. 7(10):e47644
Tu, C.T., Yang, T.C., Huang, H.Y., and Tsai, H.J. (2012) Zebrafish arl6ip1 Is Required for Neural Crest Development during Embryogenesis. PLoS One. 7(3):e32899
Umasankar, P.K., Sanker, S., Thieman, J.R., Chakraborty, S., Wendland, B., Tsang, M., and Traub, L.M. (2012) Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nature cell biology. 14(5):488-501
Witzel, H.R., Jungblut, B., Choe, C.P., Crump, J.G., Braun, T., and Dobreva, G. (2012) The LIM Protein Ajuba Restricts the Second Heart Field Progenitor Pool by Regulating Isl1 Activity. Developmental Cell. 23(1):58-70
Wu, S.Y., Shin, J., Sepich, D.S., and Solnica-Krezel, L. (2012) Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation. PLoS Biology. 10(10):e1001403
Zeng, L., and Childs, S.J. (2012) The smooth muscle microRNA miR-145 regulates gut epithelial development via a paracrine mechanism. Developmental Biology. 367(2):178-186
Alexander, C., Zuniga, E., Blitz, I.L., Wada, N., Le Pabic, P., Javidan, Y., Zhang, T., Cho, K.W., Crump, J.G., and Schilling, T.F. (2011) Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development (Cambridge, England). 138(23):5135-5146
Belting, H.G., Wendik, B., Lunde, K., Leichsenring, M., Mössner, R., Driever, W., and Onichtchouk, D. (2011) Pou5f1 contributes to dorsoventral patterning by positive regulation of vox and modulation of fgf8a expression. Developmental Biology. 356(2):323-36
Chung, M.I., Ma, A.C., Fung, T.K., and Leung, A.Y. (2011) Characterization of Sry-related HMG box group F genes in zebrafish hematopoiesis. Experimental hematology. 39(10):986-998.e5
Gallagher, T.L., Arribere, J.A., Geurts, P.A., Exner, C.R., McDonald, K.L., Dill, K.K., Marr, H.L., Adkar, S.S., Garnett, A.T., Amacher, S.L., and Conboy, J.G. (2011) Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Developmental Biology. 359(2):251-61
Gibert, Y., Sassi-Messai, S., Fini, J.B., Bernard, L., Zalko, D., Cravedi, J.P., Balaguer, P., Andersson-Lendahl, M., Demeneix, B., and Laudet, V. (2011) Bisphenol A induces otolith malformations during vertebrate embryogenesis. BMC Developmental Biology. 11(1):4
Goudevenou, K., Martin, P., Yeh, Y.J., Jones, P., and Sablitzky, F. (2011) Def6 Is Required for Convergent Extension Movements during Zebrafish Gastrulation Downstream of Wnt5b Signaling. PLoS One. 6(10):e26548
Hong, Y.J., Choi, Y.W., Myung, K.B., and Choi, H.Y. (2011) The Immunohistochemical Patterns of Calcification-related Molecules in the Epidermis and Dermis of the Zebrafish (Danio rerio). Annals of dermatology. 23(3):299-303
Huang, S., Ma, J., Liu, X., Zhang, Y., and Luo, L. (2011) Retinoic acid signaling sequentially controls visceral and heart laterality in Zebrafish. The Journal of biological chemistry. 286(32):28533-43
Just, S., Berger, I.M., Meder, B., Backs, J., Keller, A., Marquart, S., Frese, K., Patzel, E., Rauch, G.J., Tübingen 2000 Screen Consortium, Katus, H.A., and Rottbauer, W. (2011) Protein Kinase D2 Controls Cardiac Valve Formation in Zebrafish by Regulating Histone Deacetylase 5 Activity. Circulation. 124(3):324-34
Lagendijk, A.K., Goumans, M.J., Burkhard, S.B., and Bakkers, J. (2011) MicroRNA-23 Restricts Cardiac Valve Formation by Inhibiting Has2 and Extracellular Hyaluronic Acid Production. Circulation research. 109(6):649-57
Langenbacher, A.D., Nguyen, C.T., Cavanaugh, A.M., Huang, J., Lu, F., and Chen, J.N. (2011) The PAF1 complex differentially regulates cardiomyocyte specification. Developmental Biology. 353(1):19-28
Lenhart, K.F., Lin, S.Y., Titus, T.A., Postlethwait, J.H., Burdine, R.D. (2011) Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish. Development (Cambridge, England). 138(20):4405-4410
Li, C.W., and Ge, W. (2011) Spatiotemporal Expression of Bone Morphogenetic Protein Family Ligands and Receptors in the Zebrafish Ovary: A Potential Paracrine-Signaling Mechanism for Oocyte-Follicle Cell Communication. Biology of reproduction. 85(5):977-86
Li, D., Sun, H., Deng, W., Tao, D., Liu, Y., and Ma, Y. (2011) Zili Antagonizes Bmp Signaling to Regulate Dorsal-Ventral Patterning during Zebrafish Early Embryogenesis. Zoological science. 28(6):397-402
Li, Y., Li, Q., Long, Y., and Cui, Z. (2011) Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish. The Journal of biological chemistry. 286(52):45116-30
Miyasaka, K.Y., Kida, Y.S., Banjo, T., Ueki, Y., Nagayama, K., Matsumoto, T., Sato, M., and Ogura, T. (2011) Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143. Mechanisms of Development. 128(1-2):18-28
Morris, A.C., Forbes-Osborne, M.A., Pillai, L.S., and Fadool, J.M. (2011) Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration. Investigative ophthalmology & visual science. 52(5):2255-2266
Mouillesseaux, K., and Chen, J.N. (2011) Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos. PLoS One. 6(9):e25013
Patra, C., Diehl, F., Ferrazzi, F., van Amerongen, M.J., Novoyatleva, T., Schaefer, L., Mühlfeld, C., Jungblut, B., and Engel, F.B. (2011) Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish. Development (Cambridge, England). 138(20):4499-4509
Sedletcaia, A., and Evans, T. (2011) Heart chamber size in zebrafish is regulated redundantly by duplicated tbx2 genes. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(6):1548-1557
Smith, K.A., Lagendijk, A.K., Courtney, A.D., Chen, H., Paterson, S., Hogan, B.M., Wicking, C., and Bakkers, J. (2011) Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development. Development (Cambridge, England). 138(19):4193-4198
Smith, K.A., Noël, E., Thurlings, I., Rehmann, H., Chocron, S., and Bakkers, J. (2011) Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish. PLoS Genetics. 7(9):e1002289
Swartz, M.E., Sheehan-Rooney, K., Dixon, M.J., and Eberhart, J.K. (2011) Examination of a palatogenic gene program in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(9):2204-2220
Takeuchi, J.K., Lou, X., Alexander, J.M., Sugizaki, H., Delgado-Olguín, P., Holloway, A.K., Mori, A.D., Wylie, J.N., Munson, C., Zhu, Y., Zhou, Y.Q., Yeh, R.F., Henkelman, R.M., Harvey, R.P., Metzger, D., Chambon, P., Stainier, D.Y., Pollard, K.S., Scott, I.C., and Bruneau, B.G. (2011) Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nature communications. 2:187
Totong, R., Schell, T., Lescroart, F., Ryckebüsch, L., Lin, Y.F., Zygmunt, T., Herwig, L., Krudewig, A., Gershoony, D., Belting, H.G., Affolter, M., Torres-Vazquez, J., and Yelon, D. (2011) The novel transmembrane protein Tmem2 is essential for coordination of myocardial and endocardial morphogenesis. Development (Cambridge, England). 138(19):4199-4205
Verhoeven, M.C., Haase, C., Christoffels, V.M., Weidinger, G., and Bakkers, J. (2011) Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2. Birth defects research. Part A, Clinical and molecular teratology. 91(6):435-40
Wang, W.D., Melville, D.B., Montero-Balaguer, M., Hatzopoulos, A.K., and Knapik, E.W. (2011) Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population. Developmental Biology. 360(1):173-85
Wu, M.Y., Ramel, M.C., Howell, M., and Hill, C.S. (2011) SNW1 Is a Critical Regulator of Spatial BMP Activity, Neural Plate Border Formation, and Neural Crest Specification in Vertebrate Embryos. PLoS Biology. 9(2):e1000593
Wythe, J.D., Jurynec, M.J., Urness, L.D., Jones, C.A., Sabeh, M.K., Werdich, A.A., Sato, M., Yost, H.J., Grunwald, D.J., MacRae, C.A., and Li, D.Y. (2011) Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Disease models & mechanisms. 4(5):607-21
Xie, X.W., Liu, J.X., Hu, B., and Xiao, W. (2011) Zebrafish foxo3b Negatively Regulates Canonical Wnt Signaling to Affect Early Embryogenesis. PLoS One. 6(9):e24469
Xu, D.J., Bu, J.W., Gu, S.Y., Xia, Y.M., Du, J.L., and Wang, Y.W. (2011) Celecoxib Impairs Heart Development via Inhibiting Cyclooxygenase-2 Activity in Zebrafish Embryos. Anesthesiology. 114(2):391-400
Zuniga, E., Rippen, M., Alexander, C., Schilling, T.F., and Crump, J.G. (2011) Gremlin 2 regulates distinct roles of BMP and Endothelin 1 signaling in dorsoventral patterning of the facial skeleton. Development (Cambridge, England). 138(23):5147-5156
Aamar, E., and Dawid, I.B. (2010) Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(11):2980-2988
Baker, K.D., Ramel, M.C., and Lekven, A.C. (2010) A direct role for Wnt8 in ventrolateral mesoderm patterning. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(11):2828-2836
Camarata, T., Krcmery, J., Snyder, D., Park, S., Topczewski, J., and Simon, H.G. (2010) Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation. Developmental Biology. 337(2):233-245
Chung, W.S., Andersson, O., Row, R., Kimelman, D., and Stainier, D.Y. (2010) Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic β-cells in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 107(3):1142-1147
Cruz, C., Maegawa, S., Weinberg, E.S., Wilson, S.W., Dawid, I.B., and Kudoh, T. (2010) Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish embryos. Proceedings of the National Academy of Sciences of the United States of America. 107(8):3564-3569
Hartnett, L., Glynn, C., Nolan, C.M., Grealy, M., and Byrnes, L. (2010) Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos. The International journal of developmental biology. 54(4):573-583
Harvey, S.A., Tümpel, S., Dubrulle, J., Schier, A.F., and Smith, J.C. (2010) no tail integrates two modes of mesoderm induction. Development (Cambridge, England). 137(7):1127-1135
Liu, J., and Stainier, D.Y. (2010) Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish. Circulation research. 106(12):1818-1828
Mo, S., Wang, L., Li, Q., Li, J., Li, Y., Thannickal, V.J., and Cui. Z. (2010) Caveolin-1 regulates dorsoventral patterning through direct interaction with beta-catenin in zebrafish. Developmental Biology. 344(1):210-223
Nguyen, C.T., Langenbacher, A., Hsieh, M., and Chen, J.N. (2010) The Paf1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish. Developmental Biology. 341(1):167-175
Okuda, Y., Ogura, E., Kondoh, H., and Kamachi, Y. (2010) B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. PLoS Genetics. 6:e1000936
Patterson, S.E., Bird, N.C., and Devoto, S.H. (2010) BMP regulation of myogenesis in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(3):806-817
Wise, S.B., and Stock, D.W. (2010) bmp2b and bmp4 are dispensable for zebrafish tooth development. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(10):2534-2546
Znosko, W.A., Yu, S., Thomas, K., Molina, G.A., Li, C., Tsang, W., Dawid, I.B., Moon, A.M., and Tsang, M. (2010) Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development. Developmental Biology. 342(1):11-25
Abbas, L., and Whitfield, T.T. (2009) Nkcc1 (Slc12a2) is required for the regulation of endolymph volume in the otic vesicle and swim bladder volume in the zebrafish larva. Development (Cambridge, England). 136(16):2837-2848
de Pater, E., Clijsters, L., Marques, S.R., Lin, Y.F., Garavito-Aguilar, Z.V., Yelon, D., and Bakkers, J. (2009) Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development (Cambridge, England). 136(10):1633-1641
Delvaeye, M., Devriese, A., Zwerts, F., Betz, I., Moons, M., Autiero, M., and Conway, E.M. (2009) Role of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis. BMC Developmental Biology. 9:25
Dixon Fox, M., and Bruce, A.E. (2009) Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b. Development (Cambridge, England). 136(10):1675-1685
Dutton, K., Abbas, L., Spencer, J., Brannon, C., Mowbray, C., Nikaido, M., Kelsh, R.N., and Whitfield, T.T. (2009) A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle. Disease models & mechanisms. 2(1-2):68-83
Esterberg, R., and Fritz, A. (2009) dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity. Developmental Biology. 325(1):189-199
Faro, A., Boj, S.F., Ambrósio, R., van den Broek, O., Korving, J., and Clevers, H. (2009) T-Cell Factor 4 (tcf7l2) Is the Main Effector of Wnt Signaling During Zebrafish Intestine Organogenesis. Zebrafish. 6(1):59-68
Fauny, J.D., Thisse, B., and Thisse, C. (2009) The entire zebrafish blastula-gastrula margin acts as an organizer dependent on the ratio of Nodal to BMP activity. Development (Cambridge, England). 136(22):3811-3819
Feiner, N., Begemann, G., Renz, A.J., Meyer, A., and Kuraku, S. (2009) The origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomes. BMC Evolutionary Biology. 9:277
French, C.R., Erickson, T., French, D.V., Pilgrim, D.B., and Waskiewicz, A.J. (2009) Gdf6a is required for the initiation of dorsal-ventral retinal patterning and lens development. Developmental Biology. 333(1):37-47
Gestri, G., Osborne, R.J., Wyatt, A.W., Gerrelli, D., Gribble, S., Stewart, H., Fryer, A., Bunyan, D.J., Prescott, K., Collin, J.R., Fitzgerald, T., Robinson, D., Carter, N.P., Wilson, S.W., and Ragge, N.K. (2009) Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators. Human genetics. 126(6):791-803
Gosse, N.J., and Baier, H. (2009) An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina. Proceedings of the National Academy of Sciences of the United States of America. 106(7):2236-2241
Holloway, B.A., Gomez de la Torre Canny, S., Ye, Y., Slusarski, D.C., Freisinger, C.M., Dosch, R., Chou, M.M., Wagner, D.S., and Mullins, M.C. (2009) A novel role for MAPKAPK2 in morphogenesis during zebrafish development. PLoS Genetics. 5(3):e1000413
Li, X., Jia, S., Wang, S., Wang, Y., and Meng, A. (2009) Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. Blood. 114(27):5464-5472
Liu, J.X., Hu, B., Wang, Y., Gui, J.F., and Xiao, W. (2009) Zebrafish eaf1 and eaf2/u19 mediate effective convergence and extension movements through the maintenance of wnt11 and wnt5 expression. The Journal of biological chemistry. 284(24):16679-16692
Martin, E.D., Moriarty, M.A., Byrnes, L., and Grealy, M. (2009) Plakoglobin has both structural and signalling roles in zebrafish development. Developmental Biology. 327(1):83-96
Parkin, C.A., Allen, C.E., and Ingham, P.W. (2009) Hedgehog signalling is required for cloacal development in the zebrafish embryo. The International journal of developmental biology. 53(1):45-57
Peal, D.S., Burns, C.G., MacRae, C.A., and Milan, D. (2009) Chondroitin sulfate expression is required for cardiac atrioventricular canal formation. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(12):3103-3110
Rothschild, S.C., Easley, C.A. 4th, Francescatto, L., Lister, J.A., Garrity, D.M., and Tombes, R.M. (2009) Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis. Developmental Biology. 330(1):175-184
Row, R., and Kimelman, D. (2009) Bmp inhibition is necessary for post-gastrulation patterning and morphogenesis of the zebrafish tailbud. Developmental Biology. 329(1):55-63
Tse, W.K., Eisenhaber, B., Ho, S.H., Ng, Q., Eisenhaber, F., and Jiang, Y.J. (2009) Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development. BMC Genomics. 10:637
Tu, C.T., Yang, T.C., and Tsai, H.J. (2009) Nkx2.7 and Nkx2.5 function redundantly and are required for cardiac morphogenesis of zebrafish embryos. PLoS One. 4(1):e4249
Vermot, J., Forouhar, A.S., Liebling, M., Wu, D., Plummer, D., Gharib, M., and Fraser, S.E. (2009) Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart. PLoS Biology. 7(11):e1000246
Wilkinson, R.N., Pouget, C., Gering, M., Russell, A.J., Davies, S.G., Kimelman, D., and Patient, R. (2009) Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Developmental Cell. 16(6):909-916
Yue, R., Kang, J., Zhao, C., Hu, W., Tang, Y., Liu, X., and Pei, G. (2009) Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression. Cell. 139(3):535-546
Chi, N.C., Shaw, R.M., De Val, S., Kang, G., Jan, L.Y., Black, B.L., and Stainier, D.Y. (2008) Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes & Development. 22(6):734-739
Esterberg, R., Delalande, J.M., and Fritz, A. (2008) Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm. Development (Cambridge, England). 135(23):3891-3901
Flores, M.V., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2008) Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish. Nature cell biology. 10(3):346-352
Ke, Z., Kondrichin, I., Gong, Z., and Korzh, V. (2008) Combined activity of the two Gli2 genes of zebrafish play a major role in Hedgehog signaling during zebrafish neurodevelopment. Molecular and cellular neurosciences. 37(2):388-401
Leung, T., Humbert, J.E., Stauffer, A.M., Giger, K.E., Chen, H., Tsai, H.J., Wang, C., Mirshahi, T., and Robishaw, J.D. (2008) The orphan G protein-coupled receptor 161 is required for left-right patterning. Developmental Biology. 323(1):31-40
Liu, F., Walmsley, M., Rodaway, A., and Patient, R. (2008) Fli1 Acts at the Top of the Transcriptional Network Driving Blood and Endothelial Development. Current biology : CB. 18(16):1234-1240
Mehta, V., Peterson, R.E., and Heideman, W. (2008) 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure Prevents Cardiac Valve Formation in Developing Zebrafish. Toxicological sciences : an official journal of the Society of Toxicology. 104(2):303-311
Monteiro, R., van Dinther, M., Bakkers, J., Wilkinson, R., Patient, R., Ten Dijke, P., and Mummery, C. (2008) Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Developmental Biology. 315(1):55-71
Pittlik, S., Domingues, S., Meyer, A., and Begemann, G. (2008) Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts. Gene expression patterns : GEP. 8(3):141-147
Qu, X., Jia, H., Garrity, D.M., Tompkins, K., Batts, L., Appel, B., Zhong, T.P., and Baldwin, H.S. (2008) ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. Developmental Biology. 317(2):486-496
Smith, K.A., Chocron, S., von der Hardt, S., de Pater, E., Soufan, A., Bussmann, J., Schulte-Merker, S., Hammerschmidt, M., and Bakkers, J. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Developmental Cell. 14(2):287-297
Sultana, N., Nag, K., Hoshijima, K., Laird, D.W., Kawakami, A., and Hirose, S. (2008) Zebrafish early cardiac connexin, Cx36.7/Ecx, regulates myofibril orientation and heart morphogenesis by establishing Nkx2.5 expression. Proceedings of the National Academy of Sciences of the United States of America. 105(12):4763-4768
Veien, E.S., Rosenthal, J.S., Kruse-Bend, R.C., Chien, C.B., and Dorsky, R.I. (2008) Canonical Wnt signaling is required for the maintenance of dorsal retinal identity. Development (Cambridge, England). 135(24):4101-4111
Vervenne, H.B., Crombez, K.R., Lambaerts, K., Carvalho, L., Koeppen, M., Heisenberg, C.P., Van de Ven, W.J., and Petit, M.M. (2008) Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Developmental Biology. 320(1):267-277
Weber, S., Taylor, J.C., Winyard, P., Baker, K.F., Sullivan-Brown, J., Schild, R., Knüppel, T., Zurowska, A.M., Caldas-Alfonso, A., Litwin, M., Emre, S., Ghiggeri, G.M., Bakkaloglu, A., Mehls, O., Antignac, C., Schaefer, F., and Burdine, R.D. (2008) SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development. Journal of the American Society of Nephrology : JASN. 19(5):891-903
Caneparo, L., Huang, Y.L., Staudt, N., Tada, M., Ahrendt, R., Kazanskaya, O., Niehrs, C., and Houart, C. (2007) Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/betacatenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes & Development. 21(4):465-480
Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J. (2007) Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Developmental Biology. 305(2):577-588
Crotwell, P.L., and Mabee, P.M. (2007) Gene expression patterns underlying proximal-distal skeletal segmentation in late-stage zebrafish, Danio rerio. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(11):3111-3128
Esguerra, C.V., Nelles, L., Vermeire, L., Ibrahimi, A., Crawford, A.D., Derua, R., Janssens, E., Waelkens, E., Carmeliet, P., Collen, D., and Huylebroeck, D. (2007) Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination. Development (Cambridge, England). 134(24):4381-4393
Hadzhiev, Y., Lele, Z., Schindler, S., Wilson, S.W., Ahlberg, P., Straehle, U., and Mueller, F. (2007) Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish. BMC Developmental Biology. 7(1):75
Hart, D.O., Raha, T., Lawson, N.D., and Green, M.R. (2007) Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature. 450(7172):1082-1085
Klüver, N., Pfennig, F., Pala, I., Storch, K., Schlieder, M., Froschauer, A., Gutzeit, H.O., and Schartl, M. (2007) Differential expression of anti-Müllerian hormone (amh) and anti-Müllerian hormone receptor type II (amhrII) in the teleost medaka. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(1):271-281
Lee, H.C., Tsai, J.N., Liao, P.Y., Tsai, W.Y., Lin, K.Y., Chuang, C.C., Sun, C.K., Chang, W.C., and Tsai, H.J. (2007) Glycogen synthase kinase 3alpha and 3beta have distinct functions during cardiogenesis of zebrafish embryo. BMC Developmental Biology. 7(1):93
Lin, X., Rinaldo, L., Fazly, A.F., and Xu, X. (2007) Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Developmental Biology. 303(2):536-548
Lu, G., Ren, S., Korge, P., Choi, J., Dong, Y., Weiss, J., Koehler, C., Chen, J.N, and Wang, Y. (2007) A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes & Development. 21(7):784-796
Omata, Y., Nojima, Y., Nakayama, S., Okamoto, H., Nakamura, H., and Funahashi, J.I. (2007) Role of Bone morphogenetic protein 4 in zebrafish semicircular canal development. Development, growth & differentiation. 49(9):711-719
Pei, W., Noushmehr, H., Costa, J., Ouspenskaia, M.V., Elkahloun, A.G., and Feldman, B. (2007) An early requirement for maternal FoxH1 during zebrafish gastrulation. Developmental Biology. 310(1):10-22
Ribeiro, I., Kawakami, Y., Buscher, D., Raya, A., Rodriguez-Leon, J., Morita, M., Rodriguez Esteban, C., and Izpisua Belmonte, J.C. (2007) Tbx2 and Tbx3 Regulate the Dynamics of Cell Proliferation during Heart Remodeling. PLoS One. 2(1):e398
Stickney, H.L., Imai, Y., Draper, B., Moens, C. and Talbot, W.S. (2007) Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates. Developmental Biology. 310(1):71-84
Stock, D.W. (2007) Zebrafish dentition in comparative context. The Journal of experimental biology. 308(5):523-549
Tsai, I.C., Amack, J.D., Gao, Z.H., Band, V., Yost, H.J., and Virshup, D.M. (2007) A Wnt-CKIε-Rap1 Pathway Regulates Gastrulation by Modulating SIPA1L1, a Rap GTPase Activating Protein. Developmental Cell. 12(3):335-347
Varga, M., Maegawa, S., Bellipanni, G., and Weinberg, E.S. (2007) Chordin expression, mediated by Nodal and FGF signaling, is restricted by redundant function of two beta-catenins in the zebrafish embryo. Mechanisms of Development. 124(9-10):775-791
von der Hardt, S., Bakkers, J., Inbal, A., Carvalho, L., Solnica-Krezel, L., Heisenberg, C.P., and Hammerschmidt, M. (2007) The Bmp Gradient of the Zebrafish Gastrula Guides Migrating Lateral Cells by Regulating Cell-Cell Adhesion. Current biology : CB. 17(6):475-487
Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
Zhang, Y.T., Lander, A.D., and Nie, Q. (2007) Computational analysis of BMP gradients in dorsal-ventral patterning of the zebrafish embryo. Journal of theoretical biology. 248(4):579-589
Cha, Y.I., Kim, S.H., Sepich, D., Buchanan, F.G., Solnica-Krezel, L., and Dubois, R.N. (2006) Cyclooxygenase-1-derived PGE2 promotes cell motility via the G-protein-coupled EP4 receptor during vertebrate gastrulation. Genes & Development. 20(1):77-86
Cheng, L., Guo, X.F., Yang, X.Y., Chong, M., Cheng, J., Li, G., Gui, Y.H., and Lu, D.R. (2006) delta-sarcoglycan is necessary for early heart and muscle development in zebrafish. Biochemical and Biophysical Research Communications. 344(4):1290-1299
Clelland, E., Kohli, G., Campbell, R.K., Sharma, S., Shimasaki, S., and Peng, C. (2006) Bone morphogenetic protein 15 in the zebrafish ovary: cDNA cloning, genomic organization, tissue distribution and role in oocyte maturation. Endocrinology. 147(1):201-209
Connors, S.A., Tucker, J.A., and Mullins, M.C. (2006) Temporal and spatial action of Tolloid (Mini fin) and Chordin to pattern tail tissues. Developmental Biology. 293(1):191-202
Gupta, S., Zhu, H., Zon, L.I., and Evans, T. (2006) BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (Cambridge, England). 133(11):2177-2187
Hogan, B.M., Layton, J.E., Pyati, U.J., Nutt, S.L., Hayman, J.W., Varma, S., Heath, J.K., Kimelman, D., and Lieschke, G.J. (2006) Specification of the Primitive Myeloid Precursor Pool Requires Signaling through Alk8 in Zebrafish. Current biology : CB. 16(5):506-511
Kinna, G., Kolle, G., Carter, A., Key, B., Lieschke, G.J., Perkins, A., and Little, M.H. (2006) Knockdown of zebrafish crim1 results in a bent tail phenotype with defects in somite and vascular development. Mechanisms of Development. 123(4):277-287
Koppen, M., Fernandez, B.G., Carvalho, L., Jacinto, A., and Heisenberg, C.P. (2006) Coordinated cell-shape changes control epithelial movement in zebrafish and Drosophila. Development (Cambridge, England). 133(14):2671-2681
Lee, Y.M., Cope, J.J., Ackermann, G.E., Goishi, K., Armstrong, E.J., Paw, B.H., and Bischoff, J. (2006) Vascular endothelial growth factor receptor signaling is required for cardiac valve formation in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(1):29-37
Leskow, F.C., Holloway, B.A., Wang, H., Mullins, M.C., and Kazanietz, M.G. (2006) The zebrafish homologue of mammalian chimerin Rac-GAPs is implicated in epiboly progression during development. Proceedings of the National Academy of Sciences of the United States of America. 103(14):5373-5378
Lyman Gingerich, J., Lindeman, R., Putiri, E., Stolzmann, K., and Pelegri, F. (2006) Analysis of axis induction mutant embryos reveals morphogenetic events associated with zebrafish yolk extension formation. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(10):2749-2760
Maegawa, S., Varga, M., and Weinberg, E.S. (2006) FGF signaling is required for {beta}-catenin-mediated induction of the zebrafish organizer. Development (Cambridge, England). 133(16):3265-3276
Milan, D.J., Giokas, A.C., Serluca, F.C., Peterson, R.T., and MacRae, C.A. (2006) Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development (Cambridge, England). 133(6):1125-1132
Poulain, M., Fürthauer, M., Thisse, B., Thisse, C., and Lepage, T. (2006) Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling. Development (Cambridge, England). 133(11):2189-2200
Reim, G., and Brand, M. (2006) Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4. Development (Cambridge, England). 133(14):2757-2770
Rottbauer, W., Wessels, G., Dahme, T., Just, S., Trano, N., Hassel, D., Burns, C.G., Katus, H.A., and Fishman, M.C. (2006) Cardiac Myosin Light Chain-2. A Novel Essential Component of Thick-Myofilament Assembly and Contractility of the Heart. Circulation research. 99(3):323-331
Rutenberg, J.B., Fischer, A., Jia, H., Gessler, M., Zhong, T.P., and Mercola, M. (2006) Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors. Development (Cambridge, England). 133(21):4381-4390
Smith, A., Avaron, F., Guay, D., Padhi, B.K., and Akimenko, M.A. (2006) Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblast differentiation and function. Developmental Biology. 299(2):438-454
Wise, S.B., and Stock, D.W. (2006) Conservation and divergence of Bmp2a, Bmp2b, and Bmp4 expression patterns within and between dentitions of teleost fishes. Evolution & development. 8(6):511-523
Wu, K.M., Huang, C.J., Hwang, S.P., and Chang, Y.S. (2006) Molecular cloning, expression and characterization of the zebrafish bram1 gene, a BMP receptor-associated molecule. Journal of Biomedical Science. 13(3):345-355
Zhu, S., Liu, L., Korzh, V., Gong, Z., and Low, B.C. (2006) RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho Kinase and Diaphanous: Use of zebrafish as an in vivo model for GTPase signaling. Cellular Signalling. 18(3):359-372
Berman, J.N., Kanki, J.P., and Look, A.T. (2005) Zebrafish as a model for myelopoiesis during embryogenesis. Experimental hematology. 33(9):997-1006
diIorio, P.J., Runko, A., Farrell, C.A., and Roy, N. (2005) Sid4: A secreted vertebrate immunoglobulin protein with roles in zebrafish embryogenesis. Developmental Biology. 282(1):55-69
Gardiner, M.R., Daggett, D.F., Zon, L.I., and Perkins, A.C. (2005) Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(4):992-996
Gestri, G., Carl, M., Appolloni, I., Wilson, S.W., Barsacchi, G., and Andreazzoli, M. (2005) Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression. Development (Cambridge, England). 132(10):2401-2413
Ghiselli, G., and Farber, S.A. (2005) D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafish. BMC Developmental Biology. 5:19
Holzschuh, J., Wada, N., Wada, C., Schaffer, A., Javidan, Y., Tallafuss, A., Bally-Cuif, L., and Schilling, T.F. (2005) Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish. Development (Cambridge, England). 132(16):3731-3742
Huang, H., Zhang, B., Hartenstein, P.A., Chen, J.N., and Lin, S. (2005) NXT2 is required for embryonic heart development in zebrafish. BMC Developmental Biology. 5(1):7
Katoh, Y, and Katoh, M. (2005) Comparative genomics on BMP4 orthologs. International Journal of Oncology. 27(2):581-585
Kawakami, A., Nojima, Y., Toyoda, A., Takahoko, M., Satoh, M., Tanaka, H., Wada, H., Masai, I., Terasaki, H., Sakaki, Y., Takeda, H., and Okamoto, H. (2005) The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Current biology : CB. 15(5):480-488
Kozlowski, D.J., Whitfield, T.T., Hukriede, N.A., Lam, W.K., and Weinberg, E.S. (2005) The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line. Developmental Biology. 277(1):27-41
Leung, A.Y., Mendenhall, E.M., Kwan, T.T., Liang, R., Eckfeldt, C., Chen, E., Hammerschmidt, M., Grindley, S., Ekker, S.C., and Verfaillie, C.M. (2005) Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Developmental Biology. 277(1):235-254
Londin, E.R., Niemiec, J., and Sirotkin, H.I. (2005) Chordin, FGF signaling, and mesodermal factors cooperate in zebrafish neural induction. Developmental Biology. 279(1):1-19
Sarmah, B., Latimer, A.J., Appel, B., and Wente, S.R. (2005) Inositol polyphosphates regulate zebrafish left-right asymmetry. Developmental Cell. 9(1):133-145
Shimizu, T., Bae, Y.K., Muraoka, O., and Hibi, M. (2005) Interaction of Wnt and caudal-related genes in zebrafish posterior body formation. Developmental Biology. 279(1):125-141
Ulrich, F., Krieg, M., Schotz, E.M., Link, V., Castanon, I., Schnabel, V., Taubenberger, A., Mueller, D., Puech, PH., and Heisenberg, C.P. (2005) Wnt11 Functions in Gastrulation by Controlling Cell Cohesion through Rab5c and E-Cadherin. Developmental Cell. 9(4):555-564
Wilm, T.P., and Solnica-Krezel, L. (2005) Essential roles of a zebrafish prdm1/blimp1 homolog in embryo patterning and organogenesis. Development (Cambridge, England). 132(2):393-404
Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
Xie, J., and Fisher, S. (2005) Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms. Development (Cambridge, England). 132(2):383-391
Yamakoshi, K., Shishido, Y., and Shimoda, N. (2005) Generation of Aberrant Transcripts of and Free DNA Ends in Zebrafish no tail Gene. Marine biotechnology (New York, N.Y.). 7(3):163-172
Bartman, T., Walsh, E.C., Wen, K.K., McKane, M., Ren, J., Alexander, J., Rubenstein, P.A., and Stainier, D.Y. (2004) Early myocardial function affects endocardial cushion development in zebrafish. PLoS Biology. 2(5):E129
Cao, Y., Zhao, J., Sun, Z., Zhao, Z., Postlethwait, J., and Meng, A. (2004) fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos. Developmental Biology. 271(1):130-143
Fürthauer, M., Van Celst, J., Thisse, C., and Thisse, B. (2004) Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development (Cambridge, England). 131(12):2853-2864
Kaji, T., and Artinger, K.B. (2004) dlx3b and dlx4b function in the development of Rohon-Beard sensory neurons and trigeminal placode in the zebrafish neurula. Developmental Biology. 276(2):523-540
Kudoh, T., Concha, M.L., Houart, C., Dawid, I.B., and Wilson, S.W. (2004) Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. Development (Cambridge, England). 131(15):3581-3592
Little, S.C., and Mullins, M.C. (2004) Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development (Cambridge, England). 131(23):5825-5835
Marlow, F., Gonzalez, E.M., Yin, C., Rojo, C., and Solnica-Krezel, L. (2004) No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish. Development (Cambridge, England). 131(1):203-216
Nambiar, R.M., and Henion, P.D. (2004) Sequential antagonism of early and late Wnt-signaling by zebrafish colgate promotes dorsal and anterior fates. Developmental Biology. 267(1):165-80
Nojima, H., Shimizu, T., Kim, C.H., Yabe, T., Bae, Y.K., Muraoka, O., Hirata, T., Chitnis, A., Hirano, T., and Hibi, M. (2004) Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish. Mechanisms of Development. 121(4):371-386
Szeto, D.P., and Kimelman, D. (2004) Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation. Development (Cambridge, England). 131(15):3751-3760
Tsang, M., Maegawa, S., Kiang, A., Habas, R., Weinberg, E., and Dawid, I.B. (2004) A role for MKP3 in axial patterning of the zebrafish embryo. Development (Cambridge, England). 131(12):2769-2779
Agathon, A., Thisse, C., and Thisse, B. (2003) The molecular nature of the zebrafish tail organizer. Nature. 424(6947):448-452
Gering, M., Yamada, Y., Rabbitts, T.H., and Patient, R.K. (2003) Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1. Development (Cambridge, England). 130:6287-6199
Hammerschmidt, M., Kramer, C., Nowak, M., Herzog, W., and Wittbrodt, J. (2003) Loss of maternal Smad5 in zebrafish embryos affects patterning and morphogenesis of optic primordia. Developmental Dynamics : an official publication of the American Association of Anatomists. 227(1):128-133
Handrigan, G.R. (2003) Concordia discors: duality in the origin of the vertebrate tail. Journal of anatomy. 202(3):255-267
Hurlstone, A.F., Haramis, A.P., Wienholds, E., Begthel, H., Korving, J., van Eeden, F., Cuppen, E., Zivkovic, D., Plasterk, R.H., and Clevers, H. (2003) The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature. 425(6958):633-637
Lam, C.S., Sleptsova-Friedrich, I., Munro, A.D., and Korzh, V. (2003) SHH and FGF8 play distinct roles during development of noradrenergic neurons in the locus coeruleus of the zebrafish. Molecular and cellular neurosciences. 22(4):501-515
Shentu, H., Wen, H.-J., Mour Her, G., Huang, C.-J., Wu, J.-L., and Hwang, S.-P. (2003) Proximal upstream region of zebrafish bone morphogenetic protein 4 promoter directs heart expression of green fluorescent protein. Genesis (New York, N.Y. : 2000). 37(3):103-112
Sidi, S., Goutel, C., Peyriéras, N., and Rosa, F.M. (2003) Maternal induction of ventral fate by zebrafish radar. Proceedings of the National Academy of Sciences of the United States of America. 100(6):3315-3320
Trinh, L.A., Meyer, D., and Stainier, D.Y. (2003) The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish. Development (Cambridge, England). 130(20):4989-4998
Wilm, T.P. and Solnica-Krezel, L. (2003) Radar breaks the fog: Insights into dorsoventral patterning in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 100(8):4363-4365
Garrity, D.M., Childs, S., and Fishman, M.C. (2002) The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development (Cambridge, England). 129(19):4635-4645
Kramer, C., Mayr, T., Nowak, M., Schumacher, J., Runke, G., Bauer, H., Wagner, D., Schmid, B., Imai, Y., Talbot, W., Mullins, M., and Hammerschmidt, M. (2002) Maternally supplied smad5 is required for ventral specification in zebrafish embryos prior to zygotic bmp signaling. Developmental Biology. 250(2):263-279
Mathieu, J., Barth, A., Rosa, F.M., Wilson, S.W., and Peyriéras, N. (2002) Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. Development (Cambridge, England). 129(13):3055-3065
Murciano,C., Fernández, T.D., Durán, I., Maseda, D., Riuz-Sánchez, J., Becerra, J., Akimenko, M.-A., and Marí-Beffa, M. (2002) Ray-interray interactions during fin regeneration of Danio rerio. Developmental Biology. 252(2):4-224
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Mowbray, C., Hammerschmidt, M., and Whitfield, T.T. (2001) Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral line. Mechanisms of Development. 108(1-2):179-184
Payne, T.L., Postlethwait, J.H., and Yelick, P.C. (2001) Functional characterization and genetic mapping of alk8. Mechanisms of Development. 100(2):275-289
Ross, J.J., Shimmi, O., Vilmos, P., Petryk, A., Kim, H., Gaudenz, K., Hermanson, S., Ekker, S.C., O'Connor, M.B., and Marsh, J.L. (2001) Twisted gastrulation is a conserved extracellular BMP antagonist. Nature. 410(6827):479-483
Solnica-Krezel, L. and Driever, W. (2001) The role of the homeodomain protein Bozozok in zebrafish axis formation. The International journal of developmental biology. 45(1):299-310
Walsh, E.C. and Stainier, D.Y. (2001) UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science (New York, N.Y.). 293(5535):1670-1673
Bisgrove, B.W., Essner, J.J., Yost, H.J. (2000) Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development (Cambridge, England). 127(16):3567-3579
Chin, A.J., Tsang, M., and Weinberg, E.S. (2000) Heart and gut chiralities are controlled independently from initial heart position in the developing zebrafish. Developmental Biology. 227(2):403-421
Dick, A., Hild, M., Bauer, H., Imai, Y., Maifeld, H., Schier, A.F., Talbot, W.S., Bouwmeester, T., and Hammerschmidt, M. (2000) Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. Development (Cambridge, England). 127(2):343-354
Gonzalez, E.M., Fekany-Lee, K., Carmany-Rampey, A., Erter, C., Topczewski, J., Wright, C.V.E., and Solnica-Krezel, L. (2000) Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino. Genes & Development. 14(24):3087-3092
Goutel, C., Kishimoto, Y., Schulte-Merker, S., and Rosa, F. (2000) The ventralizing activity of Radar, a maternally expressed bone morphogenetic protein, reveals complex bone morphogenetic protein interactions controlling dorso-ventral patterning in zebrafish. Mechanisms of Development. 99(1-2):15-27
Griffin, K.J., Stoller, J., Gibson, M., Chen, S., Yelon, D., Stainier, D.Y., and Kimelman, D. (2000) A conserved role for H15-related T-Box transcription factors in zebrafish and Drosophila heart formation. Developmental Biology. 218(2):235-247
Howley, C. and Ho, R.K. (2000) mRNA localization patterns in zebrafish oocytes. Mechanisms of Development. 92(2):305-309
Kaufman, C.D., Martinez-Rodriguez, G., and Hackett, P.B. (2000) Ectopic expression of c-ski disrupts gastrulation and neural patterning in zebrafish. Mechanisms of Development. 95(1-2):147-162
Kawahara, A., Wilm, T., Solnica-Krezel, L., and Dawid, I.B. (2000) Functional interaction of vega2 and goosecoid homeobox genes in zebrafish. Genesis (New York, N.Y. : 2000). 28(2):58-67
Kelly, C., Chin, A.J., Leatherman, J.L., Kozlowski, D.J., and Weinberg, E.S. (2000) Maternally controlled ß-catenin-mediated signaling is required for organizer formation in the zebrafish. Development (Cambridge, England). 127(18):3899-3911
Piotrowski, T. and Nüsslein-Volhard, C. (2000) The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). Developmental Biology. 225(2):339-356
Schmid, B., Fürthauer, M., Connors, S.A., Trout, J., Thisse, B., Thisse, C., and Mullins, M.C. (2000) Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. Development (Cambridge, England). 127(5):957-967
Artinger, K.B., Chitnis, A.B., Mercola, M., and Driever, W. (1999) Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons. Development (Cambridge, England). 126(18):3969-3979
Connors, S.A., Trout, J., Ekker, M., and Mullins, M.C. (1999) The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo. Development (Cambridge, England). 126(14):3119-3130
Dick, A., Meier, A., and Hammerschmidt, M. (1999) Smad1 and Smad5 have distinct roles during dorsoventral patterning of the zebrafish embryo. Developmental Dynamics : an official publication of the American Association of Anatomists. 216(3):285-298
Fisher, S. and Halpern, M.E. (1999) Patterning the zebrafish axial skeleton requires early chordin function. Nature Genetics. 23(4):442-446
Gates, M.A., Kim, L., Egan, E.S., Cardozo, T., Sirotkin, H.I., Dougan, S.T., Lashkari, D., Abagyan, R., Schier, A.F., and Talbot, W.S. (1999) A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome research. 9(4):334-347
Gritsman, K., Zhang, J., Cheng, S., Heckscher, E., Talbot, W.S., and Schier, A.F. (1999) The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell. 97(1):121-132
Meng, A., Moore, B., Tang, H., Yuan, B., and Lin, S. (1999) A Drosophila doublesex-related gene, terra, is involved in somitogenesis in vertebrates. Development (Cambridge, England). 126:1259-1268
Miller-Bertoglio, V., Carmany-Rampey, A., Fürthauer, M., Gonzalez, E.M., Thisse, C., Thisse, B., Halpern, M.E., and Solnica-Krezel, L. (1999) Maternal and zygotic activity of the zebrafish ogon locus antagonizes BMP signaling. Developmental Biology. 214(1):72-86
Ober, E.A. and Schulte-Merker, S. (1999) Signals from the yolk cell induce mesoderm, neuroectoderm, the trunk organizer, and the notochord in zebrafish. Developmental Biology. 215(2):167-181
Schilling, T.F., Concordet, J.-P., and Ingham, P.W. (1999) Regulation of left-right asymmetries in the zebrafish by Shh and BMP4. Developmental Biology. 210(2):277-287
Thisse, C. and Thisse, B. (1999) Antivin, a novel and divergent member of the TGFß superfamily, negatively regulates mesoderm induction. Development (Cambridge, England). 126:229-240
Wang, J.M., Prefontaine, G.G., Lemieux, M.E., Pope, L., Akimenko, M.A., and Hache, R.J. (1999) Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding. Molecular and cellular biology. 19(10):7106-7122
Bauer, H., Meier, A., Hild, M., Stachel, S., Economides, A., Hazelett, D., Harland, R.M., and Hammerschmidt, M. (1998) Follistatin and Noggin are excluded from the zebrafish organizer. Developmental Biology. 204:488-507
Goldstein, A.M. and Fishman, M.C. (1998) Notochord regulates cardiac lineage in zebrafish embryos. Developmental Biology. 201:247-252
Nguyen, V.H., Schmid, B., Trout, J., Connors, S.A., Ekker, M., and Mullins, M.C. (1998) Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by bmp2b/swirl pathway of genes. Developmental Biology. 199:93-110
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18:345-349
Chen, J.-N., van Eeden, F.J.M., Warren, K.S., Chin, A., Nüsslein-Volhard, C., Haffter, P., and Fishman, M.C. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (Cambridge, England). 124(21):4373-4382
Chin, A.J., Chen, J.N., and Weinberg, E.S. (1997) Bone morphogenetic protein-4 expression characterizes inductive boundaries in organs of developing zebrafish. Development genes and evolution. 207(2):107-114
Fürthauer, M., Thisse, C., and Thisse, B. (1997) A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula. Development (Cambridge, England). 124(21):4253-4264
Hwang, S.-P.L., Tsou, M.-F., Lin, Y.-C., and Liu-C.-H. (1997) The zebrafish BMP4 gene: sequence analysis and expression pattern during embryonic development. DNA and cell biology. 16(8):1003-1011
Kishimoto, Y., Lee, K.H., Zon, L., Hammerschmidt, M., and Schulte-Merker, S. (1997) The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development (Cambridge, England). 124:4457-4466
Martinez-Barberá, J.P., H. Toresson, S. Da Rocha, and S. Krauss (1997) Cloning and expression of three members of the zebrafish Bmp family: Bmp2a, Bmp2b, and Bmp4. Gene. 198(1-2):53-59
Nikaido, M., Tada, M., Saji, T., and Ueno, N. (1997) Conservation of BMP signaling in zebrafish mesoderm patterning. Mechanisms of Development. 61(1-2):75-88
Hammerschmidt, M., Serbedzija, G.N., and McMahon, A.P. (1996) Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes & Development. 10(19):2452-2461
Additional Citations (25):
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2019) Analysis of data directly submitted to the Zebrafish International Resource Center (ZIRC). ZFIN Direct Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2016) Automated addition of links from ZFIN gene pages to SignaFish. Automated Data Submission.
ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.
Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.
ZIRC and ZFIN Staff (2007) Mutant and Transgenic Line Submissions. ZFIN Direct Data Submission.
Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of FPC Database Links. Automated Data Submission.
ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Scientific Curation. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.