ZFIN

ZFIN ID: ZDB-GENE-080104-3

ZFIN ID: ZDB-GENE-080104-3

CITATIONS (53 total)

Gene Name:	T-box transcription factor 21
Gene Symbol:	tbx21

Hui, S.P., Sugimoto, K., Sheng, D.Z., Kikuchi, K. (2022) Regulatory T cells regulate blastemal proliferation during zebrafish caudal fin regeneration. Frontiers in immunology. 13:981000

Kumar, J., Kumar, M., Sharma, S., Srivastava, N., Singh, R., Hussain, M.A., Mazumder, S. (2022) Th1-Th2 and M1-M2 interplay sculpt Aeromonas hydrophila pathogenesis in zebrafish (Danio rerio). Fish & shellfish immunology. 127:357-365

Talbot, C.D., Walsh, M.D., Cutty, S.J., Elsayed, R., Vlachaki, E., Bruce, A.E.E., Wardle, F.C., Nelson, A.C. (2022) Eomes function is conserved between zebrafish and mouse and controls left-right organiser progenitor gene expression via interlocking feedforward loops. Frontiers in cell and developmental biology. 10:982477

Farr, D.A., Nag, D., Withey, J.H. (2021) Characterization of the Immune Response to Vibrio cholerae Infection in a Natural Host Model. Frontiers in cellular and infection microbiology. 11:722520

Chen, W., Bian, C., You, X., Li, J., Ye, L., Wen, Z., Lv, Y., Zhang, X., Xu, J., Yang, S., Gu, R., Lin, X., Shi, Q. (2019) Genome Sequencing of the Japanese Eel (Anguilla japonica) for Comparative Genomic Studies on tbx4 and a tbx4 Gene Cluster in Teleost Fishes. Marine drugs. 17(7)

Giallongo, C., Tibullo, D., Camiolo, G., Parrinello, N.L., Romano, A., Puglisi, F., Barbato, A., Conticello, C., Lupo, G., Anfuso, C.D., Lazzarino, G., Li Volti, G., Palumbo, G.A., Di Raimono, F. (2019) TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma. Cell Death & Disease. 10:704

Shi, W., Shao, T., Li, J.Y., Fan, D.D., Lin, A.F., Xiang, L.X., Shao, J.Z. (2019) BTLA-HVEM Checkpoint Axis Regulates Hepatic Homeostasis and Inflammation in a ConA-Induced Hepatitis Model in Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 203(9):2425-2442

Harjula, S.E., Ojanen, M.J.T., Taavitsainen, S., Nykter, M., Rämet, M. (2018) Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection. Scientific Reports. 8:10360

Jensen, H.M., Korbut, R., Kania, P.W., Buchmann, K. (2018) Cannabidiol effects on behaviour and immune gene expression in zebrafish (Danio rerio). PLoS One. 13:e0200016

Myllymäki, H., Niskanen, M., Luukinen, H., Parikka, M., Rämet, M. (2018) Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish. Disease models & mechanisms. 11(3)

Haarder, S., Kania, P.W., Holm, T.L., von Gersdorff Jørgensen, L., Buchmann, K. (2017) Effect of ES-products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish. Parasite immunology. 39(10)

Hui, S.P., Sheng, D.Z., Sugimoto, K., Gonzalez-Rajal, A., Nakagawa, S., Hesselson, D., Kikuchi, K. (2017) Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs. Developmental Cell. 43:659-672.e5

Mehrdana, F., Kania, P.W., Nazemi, S., Buchmann, K. (2017) Immunomodulatory effects of excretory/secretory compounds from Contracaecum osculatum larvae in a zebrafish inflammation model. PLoS One. 12:e0181277

Muire, P.J., Hanson, L.A., Wills, R., Petrie-Hanson, L. (2017) Differential gene expression following TLR stimulation in rag1-/- mutant zebrafish tissues and morphological descriptions of lymphocyte-like cell populations. PLoS One. 12:e0184077

Sugimoto, K., Hui, S.P., Sheng, D.Z., Nakayama, M., Kikuchi, K. (2017) Zebrafish FOXP3 is required for the maintenance of immune tolerance. Developmental and comparative immunology. 73:156-162

Wu, S.Y., Wang, L.D., Xu, G.M., Yang, S.D., Deng, Q.F., Li, Y.Y., Huang, R. (2017) spv locus aggravates Salmonella infection of zebrafish adult by inducing Th1/Th2 shift to Th2 polarization. Fish & shellfish immunology. 67:684-691

Cao, J., Poss, K.D. (2016) Explant culture of adult zebrafish hearts for epicardial regeneration studies. Nature Protocols. 11:872-881

Dee, C.T., Nagaraju, R.T., Athanasiadis, E.I., Gray, C., Fernandez Del Ama, L., Johnston, S.A., Secombes, C.J., Cvejic, A., Hurlstone, A.F. (2016) CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes. Journal of immunology (Baltimore, Md. : 1950). 197(9):3520-3530

Xu, X.G., Hu, J.F., Ma, J.X., Nie, L., Shao, T., Xiang, L.X., Shao, J.Z. (2016) Essential Roles of TIM-1 and TIM-4 Homologs in Adaptive Humoral Immunity in a Zebrafish Model. Journal of immunology (Baltimore, Md. : 1950). 196(4):1686-99

Yang, C., Li, Z., Kang, W., Tian, Y., Yan, Y., Chen, W. (2016) TET1 and TET3 are essential in induction of Th2-type immunity partly through regulation of IL-4/13A expression in zebrafish model. Gene. 591(1):201-8

Liu, X., Wu, H., Liu, Q., Wang, Q., Xiao, J., Chang, X., Zhang, Y. (2015) Profiling immune response in zebrafish intestine, skin, spleen and kidney bath-vaccinated with a live attenuated Vibrio anguillarum vaccine. Fish & shellfish immunology. 45(2):342-5

Moreno-Mateos, M.A., Vejnar, C.E., Beaudoin, J.D., Fernandez, J.P., Mis, E.K., Khokha, M.K., Giraldez, A.J. (2015) CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nature Methods. 12:982-8

Ojanen, M.J., Turpeinen, H., Cordova, Z.M., Hammarén, M.M., Harjula, S.K., Parikka, M., Rämet, M., Pesu, M. (2015) The Proprotein Convertase Subtilisin/Kexin FurinA Regulates Zebrafish Host Response against Mycobacterium marinum. Infection and Immunity. 83(4):1431-42

Yoon, S., Mitra, S., Wyse, C., Alnabulsi, A., Zou, J., Weerdenburg, E.M., van der Sar, A.M., Wang, D., Secombes, C.J., Bird, S. (2015) First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio). PLoS One. 10:e0126378

García-Valtanen, P., Martinez-Lopez, A., Ortega-Villaizan, M., Perez, L., Coll, J.M., and Estepa, A. (2014) In addition to its antiviral and immunomodulatory properties, the zebrafish Beta-defensin 2 (zfBD2) is a potent viral DNA vaccine molecular adjuvant. Antiviral Research. 101:136-147

Hammarén, M.M., Oksanen, K.E., Nisula, H.M., Luukinen, B.V., Pesu, M., Rämet, M., Parikka, M. (2014) Adequate Th2-Type Response Associates with Restricted Bacterial Growth in Latent Mycobacterial Infection of Zebrafish. PLoS pathogens. 10:e1004190

Miyasaka, N., Arganda-Carreras, I., Wakisaka, N., Masuda, M., Sümbül, U., Seung, H.S., Yoshihara, Y. (2014) Olfactory projectome in the zebrafish forebrain revealed by genetic single-neuron labelling. Nature communications. 5:3639

Takizawa, F., Araki, K., Ohtani, M., Toda, H., Saito, Y., Lampe, V.S., Dijkstra, J.M., Ototake, M., Moritomo, T., Nakanishi, T., and Fischer, U. (2014) Transcription analysis of two Eomesodermin genes in lymphocyte subsets of two teleost species. Fish & shellfish immunology. 36(1):215-222

Zhang, H., Shen, B., Wu, H., Gao, L., Liu, Q., Wang, Q., Xiao, J., Zhang, Y. (2014) Th17-like immune response in fish mucosal tissues after administration of live attenuated Vibrio anguillarum via different vaccination routes. Fish & shellfish immunology. 37:229-38

Armant, O., März, M., Schmidt, R., Ferg, M., Diotel, N., Ertzer, R., Bryne, J.C., Yang, L., Baader, I., Reischl, M., Legradi, J., Mikut, R., Stemple, D., Ijcken, W.V., van der Sloot, A., Lenhard, B., Strähle, U., and Rastegar, S. (2013) Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos. Developmental Biology. 380(2):351-62

Wang, L., Shang, N., Feng, H., Guo, Q., and Dai, H. (2013) Molecular cloning of grass carp (Ctenopharyngodon idellus) T-bet and GATA-3, and their expression profiles with IFN-γ in response to grass carp reovirus (GCRV) infection. Fish physiology and biochemistry. 39(4):793-805

Ahn, D., You, K.H., and Kim, C.H. (2012) Evolution of the Tbx6/16 Subfamily Genes in Vertebrates: Insights from Zebrafish. Mol. Biol. Evol.. 29(12):3959-3983

Windner, S.E., Bird, N.C., Patterson, S.E., Doris, R.A., and Devoto, S.H. (2012) Fss/Tbx6 is required for central dermomyotome cell fate in zebrafish. Biology Open. 1(8):806-814

Zhu, L.Y., Pan, P.P., Fang, W., Shao, J.Z., and Xiang, L.X. (2012) Essential Role of IL-4 and IL-4Ralpha Interaction in Adaptive Immunity of Zebrafish: Insight into the Origin of Th2-like Regulatory Mechanism in Ancient Vertebrates. Journal of immunology (Baltimore, Md. : 1950). 188(11):5571-5584

Mitra, S., Alnabulsi, A., Secombes, C.J., and Bird, S. (2010) Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio. The FEBS journal. 277(1):128-147

Picozzi, P., Wang, F., Cronk, K., and Ryan, K. (2009) Eomesodermin requires TGF-beta /activin signaling and binds Smad2 to activate mesodermal genes. The Journal of biological chemistry. 284(4):2397-2408

Takizawa, F., Araki, K., Kobayashi, I., Moritomo, T., Ototake, M., and Nakanishi, T. (2008) Molecular cloning and expression analysis of T-bet in ginbuna crucian carp (Carassius auratus langsdorfii). Molecular immunology. 45(1):127-136

Additional Citations (16):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

Zebrafish Nomenclature Committee (2022) Nomenclature Data Curation (2022). Nomenclature Committee Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.