ZFIN

ZFIN ID: ZDB-GENE-061019-2

ZFIN ID: ZDB-GENE-061019-2

CITATIONS (50 total)

Gene Name:	Fas cell surface death receptor
Gene Symbol:	fas

Xie, Z., Lu, G., Zhou, R., Ma, Y. (2022) Thiacloprid-induced hepatotoxicity in zebrafish: Activation of the extrinsic and intrinsic apoptosis pathways regulated by p53 signaling pathway. Aquatic toxicology (Amsterdam, Netherlands). 246:106147

Zhao, Y., Castro, L.F.C., Monroig, Ó., Cao, X., Sun, Y., Gao, J. (2022) A zebrafish pparγ gene deletion reveals a protein kinase network associated with defective lipid metabolism. Functional & integrative genomics. 22(4):435-450

Heylen, L., Pham, D.H., De Meulemeester, A.S., Samarut, É., Skiba, A., Copmans, D., Kazwiny, Y., Vanden Berghe, P., de Witte, P.A.M., Siekierska, A. (2021) Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish. Frontiers in molecular neuroscience. 14:753936

Sun, S., Cao, X., Castro, L.F.C., Monroig, Ó., Gao, J. (2021) A network-based approach to identify protein kinases critical for regulating srebf1 in lipid deposition causing obesity. Functional & integrative genomics. 21(5-6):557-570

Xu, H., Wang, G., Chi, Y.Y., Kou, Y.X., Li, Y. (2021) Expression profiling and functional characterization of the duplicated Oxr1b gene in zebrafish. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 39:100857

Chen, C., Lu, M., Lin, S., Qin, W. (2020) The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia. Cell Death & Disease. 11:135

Eğimezer, G., Üstündağ, Ü.V., Ateş, P.S., Ünal, I., Üstündağ, F.D., Alturfan, A.A., Emekli-Alturfan, E., Altinoz, M.A., Elmaci, I. (2020) Methylnitrosourea, dimethylbenzanthracene and benzoapyrene differentially affect redox pathways, apoptosis and immunity in zebrafish. Human & Experimental Toxicology. 39(7):920-929

Gu, Q., Ali, S.F., Kanungo, J. (2020) Effects of acetyl L-carnitine on zebrafish embryos: Phenotypic and gene expression studies. Journal of applied toxicology : JAT. 41(2):256-264

Kim, Y.C., Lee, S.R., Jeon, H.J., Kim, K., Kim, M.J., Choi, S.D., Lee, S.E. (2020) Acute toxicities of fluorene, fluorene-1-carboxylic acid, and fluorene-9-carboxylic acid on zebrafish embryos (Danio rerio): Molecular mechanisms of developmental toxicities of fluorene-1-carboxylic acid. Chemosphere. 260:127622

Kwok, M.L., Hu, X.L., Meng, Q., Chan, K.M. (2020) Whole-transcriptome sequencing (RNA-seq) analyses of the zebrafish liver cell line, ZFL, after acute exposure to Cu²⁺ ions. Metallomics : integrated biometal science. 12(5):732-751

Kwok, M.L., Meng, Q., Hu, X.L., Chung, C.T., Chan, K.M. (2020) Whole-transcriptome sequencing (RNA-seq) study of the ZFL zebrafish liver cell line after acute exposure to Cd²⁺ ions. Aquatic toxicology (Amsterdam, Netherlands). 228:105628

Lan, X.R., Li, Y.W., Chen, Q.L., Shen, Y.J., Liu, Z.H. (2020) Tributyltin impaired spermatogenesis and reproductive behavior in male zebraﬁsh. Aquatic toxicology (Amsterdam, Netherlands). 224:105503

Wu, S.Y., Yang, W.Y., Cheng, C.C., Hsiao, M.C., Tsai, S.L., Lin, H.K., Lin, K.H., Yuh, C.H. (2020) Low Molecular Weight Fucoidan Prevents Radiation-Induced Fibrosis and Secondary Tumors in a Zebrafish Model. Cancers. 12(6):

Xu, H., Jiang, Y., Li, S., Xie, L., Tao, Y.X., Li, Y. (2020) Zebrafish Oxr1a Knockout Reveals Its Role in Regulating Antioxidant Defenses and Aging. Genes. 11(10):

Wu, J., Yang, Y., He, Y., Li, Q., Wang, X., Sun, C., Wang, L., An, Y., Luo, F. (2019) EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway. Human genomics. 13:63

Boskovic, S., Marín-Juez, R., Jasnic, J., Reischauer, S., El Sammak, H., Kojic, A., Faulkner, G., Radojkovic, D., Stainier, D.Y.R., Kojic, S. (2018) Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise. PLoS One. 13:e0204312

Sarasquete, C., Úbeda-Manzanaro, M., Ortiz-Delgado, J.B. (2018) Toxicity and non-harmful effects of the soya isoflavones, genistein and daidzein, in embryos of the zebrafish, Danio rerio. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 211:57-67

Wang, Y.Q., Li, Y.W., Chen, Q.L., Liu, Z.H. (2018) Long-term exposure of xenoestrogens with environmental relevant concentrations disrupted spermatogenesis of zebrafish through altering sex hormone balance, stimulating germ cell proliferation, meiosis and enhancing apoptosis. Environmental pollution (Barking, Essex : 1987). 244:486-494

Xia, J., Lu, L., Jin, C., Wang, S., Zhou, J., Ni, Y., Fu, Z., Jin, Y. (2018) Effects of short term lead exposure on gut microbiota and hepatic metabolism in adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 209:1-8

Xia, Q., Wei, L., Zhang, Y., Kong, H., Shi, Y., Wang, X., Chen, X., Han, L., Liu, K. (2018) Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder. Frontiers in pharmacology. 9:1457

Chernyavskaya, Y., Mudbhary, R., Tokarz, D., Jacob, V., Gopinath, S., Zhang, C., Sun, X., Wang, S., Magnani, E., Madakashira, B.P., Yoder, J.A., Hoshida, Y., Sadler, K.C. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). 144(16):2925-2939

Han, J., Ji, C., Guo, Y., Yan, R., Hong, T., Dou, Y., An, Y., Tao, S., Qin, F., Nie, J., Ji, C., Wang, H., Tong, J., Xiao, W., Zhang, J. (2017) Mechanisms underlying melatonin-mediated prevention of fenvalerate-induced behavioral and oxidative toxicity in zebrafish. Journal of toxicology and environmental health. Part A. 80(23-24):1331-1341

Yang, B.Y., Zhai, G., Gong, Y.L., Su, J.Z., Peng, X.Y., Shang, G.H., Han, D., Jin, J.Y., Liu, H.K., Du, Z.Y., Yin, Z., Xie, S.Q. (2017) Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American journal of physiology. Endocrinology and metabolism. 315(1):E38-E51

Yeh, K.Y., Lai, C.Y., Lin, C.Y., Hsu, C.C., Lo, C.P., Her, G.M. (2017) ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish. Scientific Reports. 7:16362

Luzio, A., Matos, M., Santos, D., Fontaínhas-Fernandes, A.A., Monteiro, S.M., Coimbra, A.M. (2016) Disruption of apoptosis pathways involved in zebrafish gonad differentiation by 17α-ethinylestradiol and fadrozole exposures. Aquatic toxicology (Amsterdam, Netherlands). 177:269-284

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Estepa, A., Coll, J. (2015) Innate Multigene Family Memories Are Implicated in the Viral-Survivor Zebrafish Phenotype. PLoS One. 10:e0135483

Lu, X., Wei, Y., Liu, F. (2015) Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish. Cell discovery. 1:15027

Ferrari, L., Pistocchi, A., Libera, L., Boari, N., Mortini, P., Bellipanni, G., Giordano, A., Cotelli, F., Riva, P. (2014) FAS/FASL are dysregulated in chordoma and their loss-of-function impairs zebrafish notochord formation. Oncotarget. 5(14):5712-5724

Her, G.M., Pai, W.Y., Lai, C.Y., Hsieh, Y.W., and Pang, H.W. (2013) Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1831(6):1037-51

Wiens, G.D., and Glenney, G.W. (2011) Origin and evolution of TNF and TNF receptor superfamilies. Developmental and comparative immunology. 35(12):1324-35

Poulton, L.D., Nolan, K.F., Anastasaki, C., Waldmann, H., and Patton, E.E. (2010) A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development. The International journal of developmental biology. 54(5):815-825

Choi, W.Y., Giraldez, A.J., and Schier, A.F. (2007) Target Protectors Reveal Dampening and Balancing of Nodal Agonist and Antagonist by miR-430. Science (New York, N.Y.). 318(5848):271-274

Eimon, P.M., Kratz, E., Varfolomeev, E., Hymowitz, S.G., Stern, H., Zha, J., and Ashkenazi, A. (2006) Delineation of the cell-extrinsic apoptosis pathway in the zebrafish. Cell death and differentiation. 13(10):1619-1630

Additional Citations (16):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.