ZFIN

ZFIN ID: ZDB-GENE-040624-12

ZFIN ID: ZDB-GENE-040624-12

CITATIONS (70 total)

Gene Name:	transient receptor potential cation channel, subfamily V, member 6
Gene Symbol:	trpv6

Liu, R., Lu, Y., Peng, X., Jia, J., Ruan, Y., Shi, S., Shu, T., Li, T., Jin, X., Zhai, G., He, J., Lou, Q., Yin, Z. (2023) Enhanced insulin activity achieved in VDRa/b ablation zebrafish. Frontiers in endocrinology. 14:10546651054665

Peloggia, J., Münch, D., Meneses-Giles, P., Romero-Carvajal, A., Lush, M.E., Lawson, N.D., McClain, M., Pan, Y.A., Piotrowski, T. (2021) Adaptive cell invasion maintains lateral line organ homeostasis in response to environmental changes. Developmental Cell. 56(9):1296-1312.e7

Pottie, L., Van Gool, W., Vanhooydonck, M., Hanisch, F.G., Goeminne, G., Rajkovic, A., Coucke, P., Sips, P., Callewaert, B. (2021) Loss of zebrafish atp6v1e1b, encoding a subunit of vacuolar ATPase, recapitulates human ARCL type 2C syndrome and identifies multiple pathobiological signatures. PLoS Genetics. 17:e1009603

Xin, Y., Guan, J., Li, Y., Duan, C. (2021) Regulation of cell quiescence-proliferation balance by Ca2+-CaMKK-Akt signaling. Journal of Cell Science. 134(20):

Chandrapalan, T., Kwong, R.W.M. (2020) Influence of dietary iron exposure on trace metal homeostasis and expression of metal transporters during development in zebrafish^☆. Environmental pollution (Barking, Essex : 1987). 261:114159

Lee, C.Y., Horng, J.L., Liu, S.T., Lin, L.Y. (2020) Exposure to copper nanoparticles impairs ion uptake, and acid and ammonia excretion by ionocytes in zebrafish embryos. Chemosphere. 261:128051

Liu, S.T., Chou, M.Y., Wu, L.C., Horng, J.L., Lin, L.Y. (2020) Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio). American journal of physiology. Regulatory, integrative and comparative physiology. 318(4):R751-R759

Tong, S.K., Lee, H.L., Lee, Y.C., Wu, L.C., Tsou, Y.L., Lu, S.W., Shih, S.W., Hwang, P.P., Chou, M.Y. (2020) Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H⁺-ATPase Rich Ionocytes. International Journal of Molecular Sciences. 21(11)

You, M.S., Yang, W.B., Cheng, C.H., Yu, S., Chang, H.C., Yu, H.S. (2020) Red LED light treatment promotes cognitive learning through up-regulation of trpm4 in zebrafish. Journal of photochemistry and photobiology. B, Biology. 213:112073

Han, J., Liu, K., Wang, R., Zhang, Y., Zhou, B. (2019) Exposure to cadmium causes inhibition of otolith development and behavioral impairment in zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 214:105236

Xin, Y., Malick, A., Hu, M., Liu, C., Batah, H., Xu, H., Duan, C. (2019) Cell-autonomous regulation of epithelial cell quiescence by calcium channel Trpv6. eLIFE. 8:

Janssens, A., Silvestri, C., Martella, A., Vanoevelen, J.M., Di Marzo, V., Voets, T. (2018) Δ⁹-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6.. Pharmacological research. 136:83-89

Liu, C., Xin, Y., Bai, Y., Lewin, G., He, G., Mai, K., Duan, C. (2018) Ca²⁺ concentration-dependent premature death of igfbp5a^-/- fish reveals a critical role of IGF signaling in adaptive epithelial growth.. Science signaling. 11(548):

Chen, J.R., Lai, Y.H., Tsai, J.J., Hsiao, C.D. (2017) Live Fluorescent Staining Platform for Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization. Molecules. 22(12)

Lin, C.H., Hu, H.J., Hwang, P.P. (2017) Molecular physiology of the hypocalcemic action of fibroblast growth factor 23 in zebrafish (Danio rerio). Endocrinology. 158(5):1347-1358

Liu, C., Dai, W., Bai, Y., Chi, C., Xin, Y., He, G., Mai, K., Duan, C. (2017) Development of a Whole Organism Platform for Phenotype-Based Analysis of IGF1R-PI3K-Akt-Tor Action. Scientific Reports. 7:1994

Pillar, N., Pleniceanu, O., Fang, M., Ziv, L., Lahav, E., Botchan, S., Cheng, L., Dekel, B., Shomron, N. (2017) A rare variant in the FHL1 gene associated with X-linked recessive hypoparathyroidism. Human genetics. 136(7):835-845

Rabinowitz, J.S., Robitaille, A.M., Wang, Y., Ray, C.A., Thummel, R., Gu, H., Djukovic, D., Raftery, D., Berndt, J.D., Moon, R.T. (2017) Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 114(5):E717-E726

Kwong, R.W., Kumai, Y., Perry, S.F. (2016) Neuroendocrine control of ionic balance in zebrafish. General and comparative endocrinology. 234:40-6

Kwong, R.W., Kumai, Y., Tzaneva, V., Azzi, E., Hochhold, N., Robertson, C., Pelster, B., Perry, S.F. (2016) Inhibition of calcium uptake during hypoxia in developing zebrafish, is mediated by hypoxia-inducible factor. The Journal of experimental biology. 219(Pt 24):3988-3995

Shu, Y., Lou, Q., Dai, Z., Dai, X., He, J., Hu, W., Yin, Z. (2016) The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models. Scientific Reports. 6:18597

Chou, M.Y., Lin, C.H., Chao, P.L., Hung, J.C., Cruz, S.A., Hwang, P.P. (2015) Stanniocalcin-1 Controls Ion Regulation Functions of Ion-transporting Epithelium Other than Calcium Balance. International journal of biological sciences. 11:122-32

Kumai, Y., Kwong, R.W., Perry, S.F. (2015) A role for transcription factor glial cell missing 2 in Ca(2+) homeostasis in zebrafish, Danio rerio. Pflugers Archiv : European journal of physiology. 467(4):753-65

Kwong, R.W., Perry, S.F. (2015) An essential role for parathyroid hormone in gill formation and differentiation of ion-transporting cells in developing zebrafish. Endocrinology. 156(7):2384-94

Kwong, R.W., Perry, S.F. (2015) Hydrogen sulfide promotes calcium uptake in larval zebrafish. American journal of physiology. Cell physiology. 309(1):C60-9

Dai, W., Bai, Y., Hebda, L., Zhong, X., Liu, J., Kao, J., and Duan, C. (2014) Calcium deficiency-induced and TRP channel-regulated IGF1R-PI3K-Akt signaling regulates abnormal epithelial cell proliferation. Cell death and differentiation. 21(4):568-81

Komjarova, I., Bury, N.R. (2014) Evidence of common cadmium and copper uptake routes in zebrafish Danio rerio. Environmental science & technology. 48(21):12946-51

Kwong, R.W., Auprix, D., and Perry, S.F. (2014) Involvement of the calcium-sensing receptor in calcium homeostasis in larval zebrafish exposed to low environmental calcium. American journal of physiology. Regulatory, integrative and comparative physiology. 306(4):R211-R221

Lin, C.H., Su, C.H., and Hwang, P.P. (2014) Calcium-sensing receptor mediates Ca2+ homeostasis by modulating expression of PTH and stanniocalcin. Endocrinology. 155(1):56-67

Zheng, D., Feeney, G.P., Handy, R.D., Hogstrand, C., and Kille, P. (2014) Uptake epithelia behave in a cell-centric and not systems homeostatic manner in response to zinc depletion and supplementation. Metallomics : integrated biometal science. 6(1):154-65

Breves, J.P., Serizier, S.B., Goffin, V., McCormick, S.D., and Karlstrom, R.O. (2013) Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill. Molecular and Cellular Endocrinology. 369(1-2):98-106

Cruz, S.A., Chao, P.L., and Hwang, P.P. (2013) Cortisol promotes differentiation of epidermal ionocytes through Foxi3 transcription factors in zebrafish (Danio rerio). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 164(1):249-257

Go, W., and Korzh, V. (2013) Plasma membrane Ca(2+) ATPase Atp2b1a regulates bone mineralization in zebrafish. Bone. 54(1):48-57

Graham, D.M., Huang, L., Robinson, K.R., and Messerli, M.A. (2013) Epidermal keratinocyte polarity and motility require Ca²⁺ influx through TRPV1. Journal of Cell Science. 126(Pt 20):4602-13

Huitema, L.F., Renn, J., Logister, I., Gray, J.K., Waltz, S.E., Flik, G., and Schulte-Merker, S. (2012) Macrophage-stimulating protein and calcium homeostasis in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(10):4092-4101

Lin, C.H., Su, C.H., Tseng, D.Y., Ding, F.C., and Hwang, P.P. (2012) Action of Vitamin D and the Receptor, VDRa, in Calcium Handling in Zebrafish (Danio rerio). PLoS One. 7(9):e45650

Liu, C.T., Chou, M.Y., Lin, C.H., and Wu, S.M. (2012) Effects of ambient cadmium with calcium on mRNA expressions of calcium uptake related transporters in zebrafish (Danio rerio) larvae. Fish physiology and biochemistry. 38(4):977-988

Chou, M.Y., Hung, J.C., Wu, L.C., Hwang, S.P., and Hwang, P.P. (2011) Isotocin controls ion regulation through regulating ionocyte progenitor differentiation and proliferation. Cellular and molecular life sciences : CMLS. 68(16):2797-809

Lafont, A.G., Wang, Y.F., Chen, G.D., Liao, B.K., Tseng, Y.C., Huang, C.J., and Hwang, P.P. (2011) Involvement of calcitonin and its receptor in the control of calcium-regulating genes and calcium homeostasis in zebrafish (Danio rerio). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 26(5):1072-1083

Lin, C.H., Tsai, I.L., Su, C.H., Tseng, D.Y., and Hwang, P.P. (2011) Reverse Effect of Mammalian Hypocalcemic Cortisol in Fish: Cortisol Stimulates Ca Uptake via Glucocorticoid Receptor-Mediated Vitamin D(3) Metabolism. PLoS One. 6(8):e23689

Vanoevelen, J., Janssens, A., Huitema, L.F., Hammond, C.L., Metz, J.R., Flik, G., Voets, T., and Schulte-Merker, S. (2011) Trpv5/6 is vital for epithelial calcium uptake and bone formation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(9):3197-207

Craig, P.M., Wood, C.M., and McClelland, G.B. (2010) Water Chemistry Alters Gene Expression and Physiological End Points of Chronic Waterborne Copper Exposure in Zebrafish, Danio rerio. Environmental science & technology. 44(6):2156-2162

Jänicke, M., Renisch, B., and Hammerschmidt, M. (2010) Zebrafish grainyhead-like1 is a common marker of different non-keratinocyte epidermal cell lineages, which segregate from each other in a Foxi3-dependent manner. The International journal of developmental biology. 54(5):837-850

Liao, B.K., Chen, R.D., and Hwang, P.P. (2009) Expression regulation of Na+-K+-ATPase {alpha}1-subunit subtypes in zebrafish gill ionocytes. American journal of physiology. Regulatory, integrative and comparative physiology. 296(6):R1897-R1906

Tseng, D.Y., Chou, M.Y., Tseng, Y.C., Hsiao, C.D., Huang, C.J., Kaneko, T., and Hwang, P.P. (2009) Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. American journal of physiology. Regulatory, integrative and comparative physiology. 296(3):R549-R557

Chou, M.Y., Hsiao, C.D., Chen, S.C., Chen, I.W., Liu, S.T., and Hwang, P.P. (2008) Effects of hypothermia on gene expression in zebrafish gills: upregulation in differentiation and function of ionocytes as compensatory responses. The Journal of experimental biology. 211(Pt 19):3077-3084

Craig, P.M., Wood, C.M., and McClelland, G.B. (2007) Gill membrane remodeling with softwater acclimation in Zebrafish (Danio rerio). Physiological Genomics. 30(1):53-60

Liao, B.K., Deng, A.N., Chen, S.C., Chou, M.Y., and Hwang, P.P. (2007) Expression and water calcium dependence of calcium transporter isoforms in zebrafish gill mitochondrion-rich cells. BMC Genomics. 8(1):354

Saito, S., and Shingai, R. (2006) Evolution of thermoTRP ion channel homologs in vertebrates. Physiological Genomics. 27(3):219-230

Pan, T.C., Liao, B.K., Huang, C.J., Lin, L.Y., and Hwang, P.P. (2005) Epithelial Ca2+ Channel Expression and Ca2+ uptake in Developing Zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 289(4):R1202-1211

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (18):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

Geisler, R. (2013) Importation of Tübingen internal allele names. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Busch-Nentwich, E., Kettleborough, R., Harvey, S., Collins, J., Ding, M., Dooley, C., Fenyes, F., Gibbons, R., Herd, C., Mehroke, S., Scahill, C., Sealy, I., Wali, N., White, R., and Stemple, D.L. (2012) Sanger Institute Zebrafish Mutation Project mutant, phenotype and image data submission. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.