ZFIN

ZFIN ID: ZDB-GENE-040426-1717

ZFIN ID: ZDB-GENE-040426-1717

CITATIONS (54 total)

Gene Name:	retinoid isomerohydrolase RPE65 a
Gene Symbol:	rpe65a

Chen, D.D., Liu, B., Wang, Y., Jiang, M., Shang, G., Xue, M., Jia, X., Lang, Y., Zhou, G., Zhang, F., Peng, X., Hu, Y. (2023) The downregulation of HSP90-controlled CRALBP expression is associated with age-related vision attenuation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37:e22832e22832

Livne, H., Avital, T., Ruppo, S., Harazi, A., Mitrani-Rosenbaum, S., Daya, A. (2022) Generation and characterization of a novel gne Knockout Model in Zebrafish. Frontiers in cell and developmental biology. 10:976111

Ying, Y., Hu, X., Han, P., Mendez-Bermudez, A., Bauwens, S., Eid, R., Tan, L., Pousse, M., Giraud-Panis, M.J., Lu, Y., Gilson, E., Ye, J. (2022) The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging. Nucleic acids research. 50(4):2081-2095

Leach, L.L., Hanovice, N.J., George, S.M., Gabriel, A.E., Gross, J.M. (2021) The immune response is a critical regulator of zebrafish retinal pigment epithelium regeneration. Proceedings of the National Academy of Sciences of the United States of America. 118(21)

Li, X., Xiong, D., Ju, Z., Xiong, Y., Ding, G., Liao, G. (2020) Phenotypic and transcriptomic consequences in zebrafish early-life stages following exposure to crude oil and chemical dispersant at sublethal concentrations. The Science of the total environment. 763:143053

Magnuson, J., Bautista, N., Lucero, J., Lund, A., Xu, E.G., Schlenk, D., Burggren, W., Roberts, A.P. (2020) Exposure to crude oil induces retinal apoptosis and impairs visual function in fish. Environmental science & technology. 54(5):2843-2850

Shi, W.J., Huang, G.Y., Jiang, Y.X., Ma, D.D., Chen, H.X., Huang, M.Z., Hou, L.P., Xie, L., Ying, G.G. (2020) Medroxyprogesterone acetate affects eye growth and the transcription of associated genes in zebrafish. Ecotoxicology and environmental safety. 193:110371

Solanki, A.K., Kondkar, A.A., Fogerty, J., Su, Y., Kim, S.H., Lipschutz, J.H., Nihalani, D., Perkins, B.D., Lobo, G.P. (2020) A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish. Cells. 9(5):

Volkov, L.I., Kim-Han, J.S., Saunders, L.M., Poria, D., Hughes, A.E.O., Kefalov, V.J., Parichy, D.M., Corbo, J.C. (2020) Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision. Proceedings of the National Academy of Sciences of the United States of America. 117(26):15262-15269

Collery, R.F., Link, B.A. (2019) Precise Short Sequence Insertion in Zebrafish Using a CRISPR/Cas9 Approach to Generate a Constitutively Soluble Lrp2 Protein. Frontiers in cell and developmental biology. 7:167

Hanovice, N.J., Leach, L.L., Slater, K., Gabriel, A.E., Romanovicz, D., Shao, E., Collery, R., Burton, E.A., Lathrop, K.L., Link, B.A., Gross, J.M. (2019) Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation. PLoS Genetics. 15:e1007939

Shi, W.J., Jiang, Y.X., Ma, D.D., Huang, G.Y., Xie, L., Chen, H.X., Huang, M.Z., Ying, G.G. (2019) Dydrogesterone affects the transcription of genes in visual cycle and circadian rhythm network in the eye of zebrafish. Ecotoxicology and environmental safety. 183:109556

Cai, S., Chen, Y., Shang, Y., Cui, J., Li, Z., Li, Y. (2018) Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment. Cell Death & Disease. 9:273

Martínez, R., Esteve-Codina, A., Herrero-Nogareda, L., Ortiz-Villanueva, E., Barata, C., Tauler, R., Raldúa, D., Piña, B., Navarro-Martín, L. (2018) Dose-dependent transcriptomic responses of zebrafish eleutheroembryos to Bisphenol A. Environmental pollution (Barking, Essex : 1987). 243:988-997

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Shi, Y., Obert, E., Rahman, B., Rohrer, B., Lobo, G.P. (2017) The Retinol Binding Protein Receptor 2 (Rbpr2) is required for Photoreceptor Outer Segment Morphogenesis and Visual Function in Zebrafish. Scientific Reports. 7:16207

Tzima, E., Serifi, I., Tsikari, I., Alzualde, A., Leonardos, I., Papamarcaki, T. (2017) Transcriptional and Behavioral Responses of Zebrafish Larvae to Microcystin-LR Exposure. International Journal of Molecular Sciences. 18(2)

Ben-Moshe Livne, Z., Alon, S., Vallone, D., Bayleyen, Y., Tovin, A., Shainer, I., Nisembaum, L.G., Aviram, I., Smadja-Storz, S., Fuentes, M., Falcón, J., Eisenberg, E., Klein, D.C., Burgess, H.A., Foulkes, N.S., Gothilf, Y. (2016) Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior. PLoS Genetics. 12:e1006445

Collery, R.F., Volberding, P.J., Bostrom, J.R., Link, B.A., Besharse, J.C. (2016) Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages. Investigative ophthalmology & visual science. 57:6805-6814

Houbrechts, A.M., Vergauwen, L., Bagci, E., Van Houcke, J., Heijlen, M., Kulemeka, B., Hyde, D.R., Knapen, D., Darras, V.M. (2016) Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function. Molecular and Cellular Endocrinology. 424:81-93

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Li, Y., Li, G., Görling, B., Luy, B., Du, J., Yan, J. (2015) Integrative Analysis of Circadian Transcriptome and Metabolic Network Reveals the Role of De Novo Purine Synthesis in Circadian Control of Cell Cycle. PLoS Computational Biology. 11:e1004086

Takamiya, M., Weger, B.D., Schindler, S., Beil, T., Yang, L., Armant, O., Ferg, M., Schlunck, G., Reinhard, T., Dickmeis, T., Rastegar, S., Strähle, U. (2015) Molecular Description of Eye Defects in the Zebrafish Pax6b Mutant, sunrise, Reveals a Pax6b-Dependent Genetic Network in the Developing Anterior Chamber. PLoS One. 10:e0117645

Zhang, L., Ma, P., Collery, R., Trowbridge, S., Zhang, M., Zhong, W., and Leung, Y.F. (2014) Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation. Molecular Vision. 20:56-72

Higdon, C.W., Mitra, R.D., and Johnson, S.L. (2013) Gene expression analysis of zebrafish melanocytes, iridophores, and retinal pigmented epithelium reveals indicators of biological function and developmental origin. PLoS One. 8(7):e67801

Konzer, A., Ruhs, A., Braun, H., Jungblut, B., Braun, T., and Krueger, M. (2013) Stable Isotope Labeling in Zebrafish Allows in Vivo Monitoring of Cardiac Morphogenesis. Molecular & cellular proteomics : MCP. 12(6):1502-12

Takahashi, Y., Moiseyev, G., Nikolaeva, O., and Ma, J.X. (2012) Identification of the key residues determining the product specificity of isomerohydrolase. Biochemistry. 51(20):4217-4225

Takahashi, Y., Moiseyev, G., Chen, Y., Farjo, K., Nikolaeva, O., and Ma, J.X. (2011) An Enzymatic Mechanism for Generating the Precursor of Endogenous 13-cis Retinoic Acid in the Brain. The FEBS journal. 278(6):973-987

Takahashi, Y., Moiseyev, G., Chen, Y., Nikolaeva, O., and Ma, J.X. (2011) An Alternative Isomerohydrolase in the Retinal Müller Cells of a Cone-Dominant Species. The FEBS journal. 278(16):2913-26

Leung, Y.F., Ma, P., and Dowling, J.E. (2007) Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Investigative ophthalmology & visual science. 48(2):881-890

Schonthaler, H.B., Lampert, J.M., Isken, A., Rinner, O., Mader, A., Gesemann, M., Oberhauser, V., Golczak, M., Biehlmaier, O., Palczewski, K., Neuhauss, S.C., and von Lintig, J. (2007) Evidence for RPE65-independent vision in the cone-dominated zebrafish retina. The European journal of neuroscience. 26(7):1940-1949

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (22):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Automatic Gene Ontology annotation based on Rhea mapping. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA, HGNC, AgBase and UniProtKB curators (2007) Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. ZFIN Direct Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.