ZFIN

ZFIN ID: ZDB-GENE-030131-8434

ZFIN ID: ZDB-GENE-030131-8434

CITATIONS (48 total)

Gene Name:	granulin a
Gene Symbol:	grna

Zambusi, A., Novoselc, K.T., Hutten, S., Kalpazidou, S., Koupourtidou, C., Schieweck, R., Aschenbroich, S., Silva, L., Yazgili, A.S., van Bebber, F., Schmid, B., Möller, G., Tritscher, C., Stigloher, C., Delbridge, C., Sirko, S., Günes, Z.I., Liebscher, S., Schlegel, J., Aliee, H., Theis, F., Meiners, S., Kiebler, M., Dormann, D., Ninkovic, J. (2022) TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury. Nature Neuroscience. 25(12):1608-1625

Campbell, C.A., Fursova, O., Cheng, X., Snella, E., McCune, A., Li, L., Solchenberger, B., Schmid, B., Sahoo, D., Morton, M., Traver, D., Espín-Palazón, R. (2021) A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Blood advances. 5:796-811

Chiang, K.Y., Li, Y.W., Li, Y.H., Huang, S.J., Wu, C.L., Gong, H.Y., Wu, J.L. (2021) Progranulin A Promotes Compensatory Hepatocyte Proliferation via HGF/c-Met Signaling after Partial Hepatectomy in Zebrafish. International Journal of Molecular Sciences. 22(20):

Zhu, J., Xu, H., Song, H., Li, X., Wang, N., Zhao, J., Zheng, X., Kim, K.Y., Zhang, H., Mao, Q., Xia, H. (2021) CRISPR/Cas9-mediated grna gene knockout leads to neurodevelopmental defects and motor behavior changes in zebrafish. Journal of neurochemistry. 157(3):520-531

Takjoo, R., Wilson, D., Bansal, P.S., Loukas, A., Smout, M.J., Daly, N.L. (2020) Folding of Truncated Granulin Peptides. Biomolecules. 10(8):

Zambusi, A., Pelin Burhan, Ö., Di Giaimo, R., Schmid, B., Ninkovic, J. (2020) Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon. Cells. 9(2):

Rougeot, J., Torraca, V., Zakrzewska, A., Kanwal, Z., Jansen, H.J., Sommer, F., Spaink, H.P., Meijer, A.H. (2019) RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection. Frontiers in immunology. 10:832

Oosterhof, N., Kuil, L.E., van der Linde, H.C., Burm, S.M., Berdowski, W., van Ijcken, W.F.J., van Swieten, J.C., Hol, E.M., Verheijen, M.H.G., van Ham, T.J. (2018) Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo. Cell Reports. 24:1203-1217.e6

Tsuruma, K., Saito, Y., Okuyoshi, H., Yamaguchi, A., Shimazawa, M., Goldman, D., Hara, H. (2018) Granulin 1 Promotes Retinal Regeneration in Zebrafish. Investigative ophthalmology & visual science. 59:6057-6066

Wang, P., Chitramuthu, B., Bateman, A., Bennett, H.P.J., Xu, P., Ni, F. (2018) Structure Dissection of Zebrafish Progranulins Identifies a Well-Folded Granulin/Epithelin Module Protein with pro-Cell Survival Activities. Protein science : a publication of the Protein Society. 27(8):1476-1490

Chitramuthu, B.P., Kay, D.G., Bateman, A., Bennett, H.P. (2017) Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS. PLoS One. 12:e0174784

Li, Y.W., Chiang, K.Y., Li, Y.H., Wu, S.Y., Liu, W., Lin, C.R., Wu, J.L. (2017) MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling. PLoS One. 12:e0177887

Walsh, C.E., Hitchcock, P.F. (2017) Progranulin regulates neurogenesis in the developing vertebrate retina. Developmental Neurobiology. 77(9):1114-1129

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Solchenberger, B., Russell, C., Kremmer, E., Haass, C., Schmid, B. (2015) Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology. PLoS One. 10:e0118956

De Muynck, L., Herdewyn, S., Beel, S., Scheveneels, W., Van Den Bosch, L., Robberecht, W., and Van Damme, P. (2013) The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding. Neurobiology of aging. 34(11):2541-7

Li, Y.H., Chen, H.Y., Li, Y.W., Wu, S.Y., Wangta, L., Lin, G.H., Hu, S.Y., Chang, Z.K., Gong, H.Y., Liao, C.H., Chiang, K.Y., Huang, C.W., and Wu, J.L. (2013) Progranulin regulates zebrafish muscle growth and regeneration through maintaining the pool of myogenic progenitor cells. Scientific Reports. 3:1176

Pietretti, D., Spaink, H.P., Falco, A., Forlenza, M., and Wiegertjes, G.F. (2013) Accessory molecules for Toll-like receptors in Teleost fish. Identification of TLR4 interactor with leucine-rich repeats (TRIL). Molecular immunology. 56(4):745-756

Schmid, B., and Haass, C. (2013) Genomic editing opens new avenues for zebrafish as a model for neurodegeneration. Journal of neurochemistry. 127(4):461-470

Wilkins, B.J., and Pack, M. (2013) Zebrafish models of human liver development and disease. Comprehensive Physiology. 3(3):1213-1230

Huang, T., Cui, J., Li, L., Hitchcock, P.F., and Li, Y. (2012) The role of microglia in the neurogenesis of zebrafish retina. Biochemical and Biophysical Research Communications. 421(2):214-220

Chitramuthu, B.P., Baranowski, D.C., Kay, D.G., Bateman, A., and Bennett, H.P. (2010) Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1. Molecular neurodegeneration. 5:41

Laird, A.S., Van Hoecke, A., De Muynck, L., Timmers, M., Van Den Bosch, L., Van Damme, P., and Robberecht, W. (2010) Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy. PLoS One. 5(10):pii: e13368

Li, Y.H., Chen, M.H., Gong, H.Y., Hu, S.Y., Li, Y.W., Lin, G.H., Lin, C.C., Liu, W., and Wu, J.L. (2010) Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. The Journal of biological chemistry. 285(52):41001-41009

Mathew, L.K., Sengupta, S., Franzosa, J., Perry, J., La Du, J., Andreasen, E.A., and Tanguay, R.L. (2009) Comparative expression profiling reveals an essential role for Raldh2 in epimorphic regeneration. The Journal of biological chemistry. 284(48):33642-33653

Shankaran, S.S., Capell, A., Hruscha, A.T., Fellerer, K., Neumann, M., Schmid, B., and Haass, C. (2008) FTLD-U linked missense mutations in the progranulin gene reduce progranulin production and secretion. The Journal of biological chemistry. 283(3):1744-1753

Lien, C.L., Schebesta, M., Makino, S., Weber, G.J., and Keating, M.T. (2006) Gene Expression Analysis of Zebrafish Heart Regeneration. PLoS Biology. 4(8):e260

Cadieux, B., Chitramuthu, B.P., Baranowski, D., and Bennett, H.P. (2005) The Zebrafish Progranulin Gene Family and Antisense Transcripts. BMC Genomics. 6(1):156

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Additional Citations (19):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

Zebrafish Nomenclature Committee (2013) Nomenclature Requests: Mutant and Transgenic Name Reservations (2013). Nomenclature Committee Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, C., and Thisse, B. (2005) High Throughput Expression Analysis of ZF-Models Consortium Clones. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.