Publication	Data		Fish	Anatomy
Williams et al., 2022	Fig. 3		ocrlsa11582/sa11582 (AB)	neuroepithelial cell receptor recycling decreased process quality, abnormal neuroepithelial cell receptor-mediated endocytosis decreased process quality, abnormal
Oltrabella et al., 2021	Fig. 5		AB + MO1-ocrl ,   ocrlumc5Tg/umc5Tg (AB)	pronephric proximal convoluted tubule endocytosis decreased process quality, abnormal pronephros decreased functionality, abnormal
Ates et al., 2020	Fig. 3.		WT + MO1-ocrl	pinocytosis decreased efficacy, abnormal
Gliozzi et al., 2019	Fig. 5		ocrlumc5Tg/umc5Tg	pronephric proximal convoluted tubule lrp2a expression decreased amount, abnormal pronephric proximal convoluted tubule decreased length, abnormal pronephric proximal straight tubule lrp2a expression decreased amount, abnormal proximal straight tubule decreased length, abnormal
	Fig. S5		ocrlumc5Tg/umc5Tg ,   AB + MO2-ocrl	pronephric proximal convoluted tubule lrp2a expression decreased amount, abnormal pronephric proximal convoluted tubule decreased length, abnormal pronephric proximal straight tubule lrp2a expression decreased amount, abnormal proximal straight tubule decreased length, abnormal
Mondin et al., 2019	Fig. 10		ocrlumc5Tg/umc5Tg	pronephric tubule endocytosis decreased occurrence, abnormal
De Leo et al., 2016	Fig. 1		ocrlumc5Tg/umc5Tg	pronephric duct lysosome increased diameter, abnormal
Oltrabella et al., 2015	Fig. 1		ocrlumc5Tg/umc5Tg ,   AB + MO1-ocrl	pronephros renal absorption decreased process quality, abnormal
	Fig. 2		ocrlumc5Tg/umc5Tg	pronephros endocytic recycling process quality, abnormal pronephros endocytosis decreased process quality, abnormal
	Fig. 4		ocrlumc5Tg/umc5Tg	pronephric duct endocytic vesicle decreased amount, abnormal pronephric duct endosome decreased amount, abnormal pronephric duct endosome increased size, abnormal
	Fig. 5		ocrlumc5Tg/umc5Tg ,   AB + MO1-ocrl	cilium assembly process quality, abnormal pronephric duct cilium decreased amount, abnormal pronephric duct cilium decreased length, abnormal pronephros renal absorption decreased process quality, abnormal
	Fig. 6		ocrlumc5Tg/umc5Tg	pronephros renal absorption decreased process quality, abnormal
	Fig. 7		ocrlumc5Tg/umc5Tg	pronephric duct endocytic vesicle decreased amount, abnormal pronephric duct endosome decreased amount, abnormal pronephric duct endosome increased size, abnormal pronephros renal absorption decreased process quality, abnormal
Luo et al., 2013	Fig. 4		WT + MO2-ocrl	cellular response to epinephrine stimulus delayed, abnormal melanocyte melanosome spatial pattern, abnormal melanosome localization disrupted, abnormal
	Fig. 7		WT + MO2-ocrl	Kupffer's vesicle cilium decreased length, abnormal
Coon et al., 2012	Fig. 3		AB/TL + MO3-ocrl	cranial vault anterior region flattened, abnormal eye decreased size, abnormal head decreased size, abnormal melanocyte decreased amount, abnormal melanocyte mislocalised, abnormal pericardium edematous, abnormal pronephros anterior region cystic, abnormal whole organism anterior-posterior axis decreased length, abnormal whole organism curled, abnormal whole organism semi-viable, abnormal
	Fig. 4		AB/TL + MO3-ocrl	cartilage development disrupted, abnormal ceratohyal cartilage malformed, abnormal ethmoid cartilage absent, abnormal heart looping disrupted, abnormal heart tube displaced to whole organism central region, abnormal heart tube displaced to whole organism right side, abnormal Meckel's cartilage decreased length, abnormal neurocranium decreased length, abnormal palatoquadrate cartilage decreased length, abnormal pharyngeal arch 3-7 lacks parts or has fewer parts of type cartilage tissue, abnormal pronephric duct motile cilium decreased length, abnormal
	Fig. S1		AB/TL + MO2-ocrl ,   ba2Tg + MO3-ocrl ,   ocrlumc5Tg/umc5Tg	eye decreased size, abnormal head decreased size, abnormal melanocyte decreased amount, abnormal melanocyte mislocalised, abnormal neural crest cell migration disrupted, abnormal neuromast immature, abnormal whole organism anterior-posterior axis decreased length, abnormal whole organism curled, abnormal
Luo et al., 2012	Fig. 5		AB/TU + MO4-ocrl ,   AB/TU + MO2-ocrl	eye decreased size, abnormal Kupffer's vesicle has fewer parts of type ciliated epithelial cell cilium, abnormal lens decreased size, abnormal post-vent region kinked, abnormal retina deformed, abnormal retina layer formation process quality, abnormal ventricular system distended, abnormal whole organism anterior-posterior axis asymmetrical, abnormal whole organism decreased pigmentation, abnormal whole organism edematous, abnormal
	Fig. S5		AB/TU + MO2-ocrl	eye decreased size, abnormal Kupffer's vesicle cilium decreased length, abnormal lens decreased size, abnormal retina deformed, abnormal whole organism decreased pigmentation, abnormal
Ramirez et al., 2012	Fig. 3		ocrlumc5Tg/umc5Tg	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity decreased occurrence, abnormal
	Fig. 4		ocrlumc5Tg/umc5Tg	cellular response to heat increased duration, abnormal forebrain neuron electrical conductivity, abnormal
	Fig. 5		ocrlumc5Tg/umc5Tg	white matter cystic, abnormal white matter increased accumulation astrocyte, abnormal
	Fig. 6		ocrlumc5Tg/umc5Tg ,   WT + MO1-ocrl	brain decreased size, abnormal eye decreased pigmentation, abnormal eye decreased size, abnormal midbrain hindbrain boundary morphology, abnormal
	Fig. 7		ocrlumc5Tg/umc5Tg	apoptotic process increased occurrence, abnormal neural precursor cell proliferation decreased occurrence, abnormal whole organism apoptotic, abnormal
	Fig. 8		ocrlumc5Tg/umc5Tg	brain apoptotic, abnormal brain decreased size, abnormal cell population proliferation decreased occurrence, abnormal spinal cord apoptotic, abnormal
	Fig. S3		ocrlumc5Tg/umc5Tg	whole organism decreased life span, abnormal
	Fig. S4		ocrlumc5Tg/umc5Tg	whole organism decreased length, abnormal
	Fig. S7		WT + MO1-ocrl ,   ocrlumc5Tg/umc5Tg	brain decreased size, abnormal
Rbaibi et al., 2012	Fig. 2		WT + MO2-ocrl	brain hydrocephalic, abnormal embryo development disrupted, abnormal pericardium edematous, abnormal whole organism increased curvature, abnormal
	Fig. 3		WT + MO2-ocrl	renal filtration disrupted, abnormal
	Fig. 4		WT + MO2-ocrl	pronephric tubule cilium disorganized, abnormal pronephric tubule cilium increased length, abnormal pronephric tubule increased width, abnormal