Phenotype Summary

Fish:	dmd^{ta222a/ta222a}
Conditions:	All

Phenotypes

Publication	Data	Phenotype
Smith et al., 2021	Fig. 4	lysosome localization occurrence, normal
Stocco et al., 2021	Fig. 2	myotome fibrotic, abnormal myotome structure, ameliorated skeletal muscle disorganized, abnormal
	Fig. 3	regulation of mitochondrial membrane potential disrupted, abnormal regulation of mitochondrial membrane potential normal process quality, ameliorated
	Fig. 4	regulation of mitochondrial membrane potential disrupted, abnormal regulation of mitochondrial membrane potential normal process quality, ameliorated trunk apoptotic process increased occurrence, abnormal trunk apoptotic process normal occurrence, ameliorated trunk reactive oxygen species increased amount, abnormal trunk reactive oxygen species normal amount, ameliorated
	Fig. 5	swimming decreased rate, abnormal swimming normal rate, ameliorated whole organism alive, ameliorated whole organism dead, abnormal
	Fig. 6	fast muscle cell fragmented, abnormal fast muscle cell mitochondrial outer membrane attached to fast muscle cell mitochondrial inner membrane, ameliorated fast muscle cell mitochondrial outer membrane detached from fast muscle cell mitochondrial inner membrane, abnormal fast muscle cell mitochondrial outer membrane increased distance fast muscle cell mitochondrial inner membrane, abnormal fast muscle cell mitochondrial outer membrane normal distance fast muscle cell mitochondrial inner membrane, ameliorated fast muscle cell morphology, ameliorated slow muscle cell morphology, normal
	Fig. 7	fast muscle cell fragmented, abnormal fast muscle cell mitochondrial outer membrane attached to fast muscle cell mitochondrial inner membrane, ameliorated fast muscle cell mitochondrial outer membrane detached from fast muscle cell mitochondrial inner membrane, abnormal fast muscle cell mitochondrial outer membrane increased distance fast muscle cell mitochondrial inner membrane, abnormal fast muscle cell mitochondrial outer membrane normal distance fast muscle cell mitochondrial inner membrane, ameliorated fast muscle cell morphology, ameliorated slow muscle cell morphology, normal
	Fig. 8	fast muscle cell mitochondrial outer membrane increased distance fast muscle cell mitochondrial inner membrane, abnormal fast muscle cell mitochondrial outer membrane normal distance fast muscle cell mitochondrial inner membrane, ameliorated
	Fig. 9	muscle cell mitochondrion morphology, normal muscle cell morphology, normal muscle cell sarcolemma dmd expression absent, abnormal
Berger et al., 2020	Fig. 2	muscle cell decreased amount, abnormal
	Fig. 3	muscle contraction decreased magnitude, abnormal muscle contraction decreased magnitude, ameliorated
	Fig. 5	whole organism dmd expression decreased amount, abnormal
Farr et al., 2020	Fig. 2	skeletal muscle refractivity, abnormal trunk musculature lesioned, abnormal
	Fig. 6	trunk musculature refractivity, ameliorated
	Fig. 7-1	trunk musculature ab1-dmd labeling absent, abnormal
	Fig. 8	histone acetyltransferase activity increased process quality, abnormal
Lasa-Fernandez et al., 2020	Fig. 2	trunk musculature reflectivity, abnormal
Spinazzola et al., 2020	Fig. 1.	skeletal muscle refractivity, abnormal
	Fig. 2.	skeletal muscle refractivity, abnormal skeletal muscle refractivity, ameliorated
Hall et al., 2019	Fig. 1	muscle cell dead, abnormal
Hightower et al., 2019	Fig. 1	muscle morphology, abnormal muscle morphology, ameliorated
Serafini et al., 2018	Fig. 2	locomotory behavior decreased occurrence, abnormal
Goody et al., 2017	Fig. 5	skeletal muscle cell damaged, abnormal skeletal muscle cell damaged, exacerbated skeletal muscle cell degenerate, abnormal skeletal muscle cell degenerate, exacerbated whole organism decreased life span, exacerbated
Schiavone et al., 2017	Fig. 4	muscle mitochondrial crista decreased amount, abnormal muscle mitochondrial crista morphology, ameliorated muscle mitochondrial matrix decreased mass density, abnormal muscle mitochondrion increased size, abnormal skeletal muscle myofibril attachment quality skeletal muscle muscle tendon junction, ameliorated skeletal muscle myofibril detached from skeletal muscle muscle tendon junction, abnormal
	Fig. 5	muscle mitochondrion increased size, abnormal muscle mitochondrion morphology, ameliorated skeletal muscle myofibril attachment quality skeletal muscle muscle tendon junction, ameliorated skeletal muscle myofibril detached from skeletal muscle muscle tendon junction, abnormal
	Fig. 6	fast muscle cell mitochondrion swollen, abnormal slow muscle cell mitochondrion morphology, normal
	Fig. 7	whole organism dead, abnormal whole organism decreased life span, abnormal whole organism life span, ameliorated whole organism refractivity, abnormal whole organism refractivity, ameliorated whole organism respiratory gaseous exchange by respiratory system process quality, abnormal whole organism respiratory gaseous exchange by respiratory system process quality, ameliorated
Smith et al., 2017	Fig. 6	musculoskeletal movement magnitude, normal
Vieira et al., 2017	Fig. 3	myotome sarcomere malformed, abnormal myotome skeletal muscle cell ab-f59 labeling spatial pattern, abnormal myotome skeletal myofibril assembly decreased process quality, abnormal swimming decreased occurrence, abnormal
Lipscomb et al., 2016	Fig. 1	whole organism dag1 expression decreased amount, abnormal
	Fig. 5	whole organism dag1 expression amount, ameliorated whole organism dag1 expression decreased amount, abnormal
	Fig. 6	whole organism dag1 expression amount, ameliorated whole organism dag1 expression increased amount, abnormal
	Fig. 7	myotome skeletal myofibril assembly decreased process quality, abnormal myotome skeletal myofibril assembly process quality, ameliorated
	Fig. 8	swimming decreased occurrence, abnormal swimming occurrence, ameliorated
Widrick et al., 2016	text only	skeletal muscle adaptation disrupted, abnormal tonic skeletal muscle contraction decreased intensity, abnormal trunk musculature relaxation of muscle increased duration, abnormal trunk musculature sarcomere decreased diameter, abnormal trunk musculature sarcomere decreased length, abnormal trunk musculature sarcomere increased diameter, abnormal twitch skeletal muscle contraction decreased intensity, abnormal twitch skeletal muscle contraction increased duration, abnormal
Li et al., 2015	Fig. 1	skeletal muscle cell alignment skeletal muscle, abnormal skeletal muscle cell disorganized, abnormal skeletal muscle cell undulate, abnormal skeletal muscle deformed, abnormal skeletal muscle disorganized, abnormal skeletal muscle disorganized, ameliorated skeletal muscle structure, abnormal skeletal muscle structure, ameliorated
	Fig. 3	skeletal muscle structure, abnormal skeletal muscle structure, ameliorated
	Fig. 4	skeletal muscle decreased strength, abnormal
	Fig. 5	skeletal muscle decreased strength, abnormal skeletal muscle disorganized, ameliorated
	text only	whole organism immobile, abnormal
Smith et al., 2015	Fig. 3	trunk musculature membrane damage, abnormal
Vieira et al., 2015	Fig. 4	muscle refractivity, abnormal skeletal muscle cell disorganized, abnormal
Vågberg et al., 2015	Fig. 4	muscle myofibril patchy, abnormal muscle structure, abnormal
Kawahara et al., 2014	Fig. 2	skeletal muscle broken, abnormal skeletal muscle broken, normal skeletal muscle dystrophic, abnormal skeletal muscle dystrophic, normal
Li et al., 2014	Fig. 1	muscle structure, abnormal
	Fig. 2	muscle contraction process quality, abnormal muscle decreased functionality, abnormal muscle decreased strength, abnormal
	Fig. 4	muscle disorganized, abnormal muscle structure, abnormal
Waugh et al., 2014	Fig. 3	myotome skeletal muscle myofibril disorganized, abnormal myotome skeletal muscle myofibril organized, normal skeletal myofibril assembly decreased process quality, abnormal skeletal myofibril assembly process quality, normal
	Fig. 4	myotome skeletal muscle myofibril disorganized, abnormal skeletal myofibril assembly decreased process quality, abnormal
	Fig. 5	skeletal muscle cell sarcolemma increased permeability, abnormal skeletal muscle cell sarcolemma permeability, normal
	Fig. 6	myotome skeletal muscle myofibril increased fragility, abnormal
	Fig. 7	myotome skeletal muscle myofibril malformed, abnormal myotome skeletal muscle myofibril morphology, normal vertical myoseptum physical object quality, abnormal
	Fig. 8	intracellular calcium ion homeostasis process quality, abnormal intracellular calcium ion homeostasis process quality, normal
	Fig. S3	myotome skeletal muscle myofibril disorganized, abnormal skeletal myofibril assembly decreased process quality, abnormal
Johnson et al., 2013	Fig. 4	muscle broken, abnormal myotome broken, abnormal
	Fig. 5	muscle broken, abnormal muscle broken, normal
Sztal et al., 2012	Fig. 1	muscle damaged, abnormal muscle dystrophic, abnormal myotome refractivity, abnormal skeletal muscle cell detached from myoseptum, abnormal
	Fig. 2	fast muscle cell detached from myoseptum, abnormal slow muscle cell detached from myoseptum, abnormal
Kawahara et al., 2011	Fig. 2	myoseptum dmd expression absent, abnormal skeletal muscle structure, abnormal skeletal muscle structure, ameliorated
	Fig. 4	skeletal muscle cell broken, abnormal skeletal muscle cell morphology, abnormal skeletal muscle cell structure, abnormal skeletal muscle disorganized, abnormal skeletal muscle structure, ameliorated
	Fig. 5	skeletal muscle structure, abnormal skeletal muscle structure, ameliorated
Winder et al., 2011	Fig. 1	muscle dystrophic, abnormal muscle organization quality, abnormal whole organism refractivity, abnormal
Berger et al., 2010	Fig. 2	skeletal muscle atrophied, abnormal skeletal muscle cell degenerate, abnormal skeletal muscle cell increased variability of size, abnormal skeletal muscle cell myofibril increased contractility, abnormal skeletal muscle fiber development disrupted, abnormal
	Fig. 3	skeletal muscle cell increased variability of size, abnormal skeletal muscle cell nucleus mislocalised, abnormal skeletal muscle fiber development disrupted, abnormal
	Fig. 4	skeletal muscle increased accumulation skeletal muscle cell fibrillar collagen trimer, abnormal skeletal muscle neutrophil aggregated, abnormal skeletal muscle neutrophil present, abnormal
	Fig. 5	skeletal muscle satellite cell proliferation increased occurrence, abnormal
	Fig. 6	skeletal muscle cell broken, abnormal
Jacoby et al., 2009	Fig. 1	myotome skeletal muscle cell decreased amount, abnormal myotome skeletal muscle cell degeneration, abnormal