Paone et al., 2018 - Genetics of Cardiovascular Disease: Fishing for Causality. Frontiers in cardiovascular medicine   5:60 Full text @ Front Cardiovasc Med

Figure 1

GWAS and zebrafish: a powerful combination for cardiovascular research. The benefits of the zebrafish as an experimental system can enormously help to validate the functional relevance of candidate genes identified by GWA studies. In addition, the system enables the in vivo analysis of underlying pathomechanisms and is highly suitable for high throughput screening applications. In summary, the combination of GWAS and the zebrafish experimental system has the potential to lead to improved and specific therapeutic approaches.

Acknowledgments:
ZFIN wishes to thank the journal Frontiers in cardiovascular medicine for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Front Cardiovasc Med