Spikol et al., 2016 - Zebrafish Models of Prader-Willi Syndrome: Fast Track to Pharmacotherapeutics. Diseases (Basel, Switzerland)   4(1) Full text @ Diseases

Figure 1

Overview of approaches for investigating PWS using zebrafish. (I) Genes and molecular pathways can be genetically or pharmacologically perturbed. (II) The effect of perturbations can be evaluated using a variety of phenotypic analyses. PWS endophenotypes may then be utilized as disease models and subjected to drug screening to identify potential pharmacotherapeutics.

Acknowledgments:
ZFIN wishes to thank the journal Diseases (Basel, Switzerland) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Diseases