FIGURE SUMMARY
Title

Neural stem/progenitor cells in Alzheimer's disease

Authors
Tincer, G., Mashkaryan, V., Bhattarai, P., Kizil, C.
Source

A simplified sketch showing the effects of Aβ deposition in mouse brain on stem cell proliferation, transient amplifying progenitor proliferation, neuronal differentiation and maturation. Aβ42 through infusion or transgenic APPswe/PS1 suppressed NSPC proliferation, while PDGF-driven APPswe,Ind increases the differentiation of progenitors to neurons. NSC: neural stem cell; TAP: transiently amplifying cells, IN: immature neuron. See text for details.

Acknowledgments
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