BMAA reduces heart rate, but does not alter larvae phenotype.
Zebrafish embryos were injected at the one-cell stage with 4.2 nL (6.5 ng) of BMAA, equivalent volume of solvent control or left un-injected. (A) Box plot of heart rate (beats/min) measured at 3 dpf. Middle line in box represents the median, lower box bound the first quartile, and upper box bound the third quartile. n = 19–37 from two independent experiments, p < 0.001 (B) Un-injected larvae at 4 dpf. (C) BMAA-injected larvae at 4 dpf.
|Acknowledgments:||ZFIN wishes to thank the journal Scientific Reports for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Sci. Rep.|