ZFIN All Figures, Chen <i>et al.</i>, 2016

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	nr0b1
Fish:	AB
Anatomical Terms:	gonad gonad primordium immature gonad ovary testis
Stage Range:	Days 7-13 to Days 30-44

Expression / Labeling details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	ddx4 nr0b1
Antibody:	Ab4-lam
Fish:	AB
Anatomical Terms:	immature gonad basement membrane immature gonad germ line cell immature gonad somatic cell somatic cell basement membrane
Stage:	Days 14-20

Expression / Labeling details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB) nr0b1^zf716/zf716 (AB) nr0b1^zf716/zf716 (AB) nr0b1^zf716/+ (AB) nr0b1^zf716/+ (AB) nr0b1^zf716/+ (AB)
Observed In:	female sex determination male sex determination
Stage:	Adult

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	ddx4 nanos3
Fish:	AB nr0b1^zf716/zf716 (AB)
Anatomical Terms:	immature gonad germ line cell whole organism
Stage Range:	Days 7-13 to Days 14-20

Expression / Labeling details

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB)
Observed In:	germ line cell immature gonad immature gonad germ cell development whole organism
Stage Range:	Days 7-13 to Days 14-20

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	tp53
Antibody:	Ab1-casp3
Fish:	AB nr0b1^zf716/zf716 (AB)
Anatomical Terms:	gonad primordium immature gonad
Stage Range:	Days 7-13 to Days 21-29

Expression / Labeling details

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB)
Observed In:	immature gonad apoptotic process
Stage Range:	Days 7-13 to Days 21-29

Phenotype details

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB) nr0b1^zf716/zf716 (AB) nr0b1^zf716/+ (AB) tp53^zdf1/+; nr0b1^zf716/+ (AB) tp53^zdf1/+; nr0b1^zf716/zf716 (AB) tp53^zdf1/+; nr0b1^zf716/zf716 (AB) tp53^zdf1/zdf1; nr0b1^zf716/+ (AB) tp53^zdf1/zdf1; nr0b1^zf716/zf716 (AB) tp53^zdf1/zdf1; nr0b1^zf716/zf716 (AB)
Observed In:	female sex determination male sex determination
Stage:	Adult

Phenotype details

Fig. 8

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB)
Observed In:	gonad cell population proliferation
Stage:	Days 21-29

Phenotype details

Fig. 9

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB)
Observed In:	germ line cell cell population proliferation gonad cell population proliferation somatic cell cell population proliferation
Stage:	Days 21-29

Phenotype details

Fig. 10

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	amh cyp19a1a foxl2a
Fish:	AB nr0b1^zf716/zf716 (AB)
Anatomical Terms:	gonad primordium immature gonad immature gonad somatic cell
Stage Range:	Days 7-13 to Days 14-20

Expression / Labeling details

PHENOTYPE:

Fish:	nr0b1^zf716/zf716 (AB)
Observed In:	gonad primordium immature gonad immature gonad female gonad development immature gonad female somatic sex determination immature gonad male gonad development immature gonad male somatic sex determination immature gonad somatic cell
Stage Range:	Days 7-13 to Days 14-20

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Molecular and Cellular Endocrinology, 433, Chen, S., Zhang, H., Wang, F., Zhang, W., Peng, G., nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation, 105-16, Copyright (2016) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.

Chen et al., 2016 ZDB-PUB-160610-17 PMID:27267667

nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation

Chen et al., 2016

ZDB-PUB-160610-17
PMID:27267667