FIGURE SUMMARY
- Title
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Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos
- Authors
- McDougall, M.Q., Choi, J., Stevens, J.F., Truong, L., Tanguay, R.L., Traber, M.G.
- Source
- Full text @ Redox Biol.
E- embryos have morphological defects and increased mortality compared to E+ embryos. Representative pictures from the two diet groups at 120 hours post-fertilization (hpf). A. Uninflated swim bladders in elsewise morphologically normal E- embryos that survived to this stage. B. An E+ embryo provided for comparison. Morphological evaluations were made using the zebrafish acquisition and analysis program (ZAAP). Phenotypic differences in E- embryos became evident between 48 and 72 hpf, with most mortalities occurring by 72 hpf. By 120 hpf, 75-88% of E- embryos from each spawn were malformed or dead. |
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Full text @ Redox Biol.