ZFIN All Figures, Kearns <i>et al.</i>, 2015

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	cldnk dhrs12 fdps hmgcra hmgcs1 mbpa mpz plp1a
Antibody:	Ab1-mbp
Fish:	WT fbxw7^vu56/vu56
Anatomical Terms:	spinal cord dorso-lateral margin spinal cord medial region spinal cord myelin sheath spinal cord oligodendrocyte spinal cord ventral margin whole organism
Stage Range:	Day 4 to Days 7-13

Expression / Labeling details

PHENOTYPE:

Fish:	fbxw7^vu56/vu56
Observed In:	spinal cord central nervous system myelination spinal cord medial region spinal cord myelin sheath spinal cord oligodendrocyte whole organism whole organism cholesterol biosynthetic process
Stage Range:	Day 4 to Days 7-13

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	cldnk dhrs12 fdps hmgcra hmgcs1 mbpa mpz plp1a
Antibodies:	Ab1-mbp Ab1-sox10
Fish:	WT mtor^{xu015Gt/xu015Gt}
Anatomical Terms:	spinal cord oligodendrocyte whole organism
Stage Range:	Day 4 to Days 7-13

Expression / Labeling details

PHENOTYPE:

Fish:	mtor^{xu015Gt/xu015Gt}
Observed In:	oligodendrocyte spinal cord spinal cord central nervous system myelination spinal cord myelin sheath spinal cord oligodendrocyte whole organism whole organism cholesterol biosynthetic process
Stage Range:	Day 4 to Days 7-13

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	cldnk dhrs12 fdps hmgcra hmgcs1 mbpa mpz plp1a
Antibody:	Ab1-mbp
Fish:	WT fbxw7^vu56/vu56 mtor^{xu015Gt/xu015Gt} fbxw7^vu56/vu56; mtor^{xu015Gt/xu015Gt}
Condition:	chemical treatment: sirolimus
Anatomical Terms:	spinal cord oligodendrocyte whole organism
Stage Range:	Day 4 to Days 7-13

Expression / Labeling details

PHENOTYPE:

Fish:	WT fbxw7^vu56/vu56 mtor^{xu015Gt/xu015Gt} fbxw7^vu56/vu56; mtor^{xu015Gt/xu015Gt}
Condition:	chemical treatment: sirolimus
Observed In:	oligodendrocyte spinal cord spinal cord oligodendrocyte whole organism
Stage Range:	Day 4 to Days 7-13

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	EGFP
Antibody:	Ab1-rps6
Fish:	WT fbxw7^vu56/vu56 mtor^{xu015Gt/xu015Gt} vu12Tg fbxw7^vu56/vu56; vu12Tg
Condition:	chemical treatment: sirolimus
Anatomical Terms:	spinal cord oligodendrocyte whole organism
Stage Range:	Day 4 to Days 7-13

Expression / Labeling details

PHENOTYPE:

Fish:	WT fbxw7^vu56/vu56 mtor^{xu015Gt/xu015Gt} vu12Tg fbxw7^vu56/vu56; vu12Tg
Condition:	chemical treatment: sirolimus
Observed In:	oligodendrocyte TOR signaling spinal cord oligodendrocyte whole organism whole organism TOR signaling
Stage Range:	Day 4 to Days 7-13

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Acknowledgments

Full text @ J. Neurosci.

Kearns et al., 2015

ZDB-PUB-151106-4
PMID:26538655

Fbxw7 Limits Myelination by Inhibiting mTOR Signaling

Kearns et al., 2015 ZDB-PUB-151106-4 PMID:26538655

Fbxw7 Limits Myelination by Inhibiting mTOR Signaling

Kearns et al., 2015

ZDB-PUB-151106-4
PMID:26538655