ZFIN All Figures, Weaver <i>et al.</i>, 2015

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	polr1a
Fish:	AB
Anatomical Terms:	brain eye immature eye lens midbrain hindbrain boundary otic vesicle somite whole organism
Stage Range:	2-cell to Protruding-mouth

Expression / Labeling details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	polr1a^{hi3639Tg/hi3639Tg}
Observed In:	brain ceratobranchial cartilage ceratohyal cartilage eye head mandibular arch skeleton otic vesicle pectoral fin pericardium pigmentation post-vent region swim bladder whole organism
Stage Range:	10-13 somites to Day 5

Phenotype details

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	polr1a^{hi3639Tg/hi3639Tg}
Observed In:	cranial ganglion embryonic viscerocranium morphogenesis mandibular arch skeleton neuron development pectoral fin
Stage Range:	Protruding-mouth to Day 5

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	dlx2a sox2 sox9a sox10
Fish:	AB polr1a^{hi3639Tg/hi3639Tg}
Anatomical Terms:	cranial neural crest cell neural crest cell neural plate pharyngeal arch 3-7 neural crest cell
Stage Range:	5-9 somites to Prim-25

Expression / Labeling details

PHENOTYPE:

Fish:	polr1a^{hi3639Tg/hi3639Tg}
Observed In:	cranial neural crest cell pharyngeal arch 3-7
Stage Range:	14-19 somites to Prim-25

Phenotype details

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	polr1a^{hi3639Tg/hi3639Tg}; ir937Tg
Observed In:	apoptotic process neural crest cell development neural tube
Stage Range:	10-13 somites to Prim-5

Phenotype details

Fig. 8

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	tp53
Fish:	AB polr1a^{hi3639Tg/hi3639Tg}
Anatomical Term:	whole organism
Stage Range:	Prim-5 to Day 4

Expression / Labeling details

PHENOTYPE:

Fish:	polr1a^{hi3639Tg/hi3639Tg}
Observed In:	ribosome biogenesis
Stage:	Prim-5

Phenotype details

Acknowledgments

Full text @ Am. J. Hum. Genet.

Weaver et al., 2015

ZDB-PUB-150429-13
PMID:25913037

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction

Weaver et al., 2015 ZDB-PUB-150429-13 PMID:25913037

Acrofacial Dysostosis, Cincinnati Type, a Mandibulofacial Dysostosis Syndrome with Limb Anomalies, Is Caused by POLR1A Dysfunction

Weaver et al., 2015

ZDB-PUB-150429-13
PMID:25913037