Armas et al., 2013 - Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets of CNBP during Embryonic Development. PLoS One   8(5):e63234 Full text @ PLoS One

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Prim-5

Fig. 6 CNBP depletion reduces the expression of tbx2b in territories overlapping with cnbp.

Expression pattern of tbx2b and cnbp analyzed by whole-mount in situ hybridization in 15 and 24-hpf-staged zebrafish embryos microinjected with mis-MO (A–D and I–L) or spl-MO (E-H and M–P) morpholinos. Anterior is at the left. Scale bar (200 μm) is represented in C and K. Tbx2b expression territories affected in morphant embryos are marked with dashed-line ovals. Number and percentages of morphant phenotypes are indicated for each embryo stage. Cnbp expression pattern in control embryos (microinjected with mis-MO) is coincident with that described elsewhere [4] and mainly overlapping with tbx2b expression in the eye territory. Morphant embryos showed a dramatically reduced cnbp expression level in those territories wherein it is normally expressed. vdc, ventral diencephalon; e, eye; ep, epiphysis; mhb, midbrain–hindbrain border; ov, otic vesicle; tg, trigeminal ganglion.

Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One