Loucks et al., 2007 - Molecular changes associated with teratogen-induced cyclopia. Birth Defects Research Part A: Clinical and Molecular Teratology   79(9):642-651 Full text @ Birth Defects Res. A Clin. Mol. Teratol.

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:
Fish: smob641/b641
Observed In: eye, post-vent region
Stage: Day 5

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: gsc, six3b, tdgf1
Fish: EKW
Conditions: chemical treatment: Cyclopamine, chemical treatment: forskolin, chemical treatment: ethanol
Anatomical Terms: hypoblast, neuroectoderm, prechordal plate, unspecified
Stage: 75%-epiboly

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: otx1b, pax6a, rx3, six3b
Fish: EKW
Conditions: chemical treatment: Cyclopamine, chemical treatment: forskolin, chemical treatment: ethanol
Anatomical Terms: diencephalon, hindbrain, immature eye, midbrain, optic stalk (all 7) expand
Stage: Prim-5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: dlx3b, pax2a, sox3
Fish: EKW
Conditions: chemical treatment: Cyclopamine, chemical treatment: forskolin, chemical treatment: ethanol
Anatomical Terms: hindbrain, immature eye, neural tube, olfactory placode, optic stalk (all 8) expand
Stage: Prim-5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: dlx3b, gli1, gsc, otx1b, otx2 (all 11) expand
Fish: EKW
Conditions: chemical treatment: Cyclopamine, chemical treatment: forskolin, chemical treatment: ethanol
Anatomical Term: whole organism
Stage Range: 75%-epiboly to Prim-5
Full text @ Birth Defects Res. A Clin. Mol. Teratol.