Schlueter et al., 2007 - Insulin-like growth factor signaling regulates zebrafish embryonic growth and development by promoting cell survival and cell cycle progression. Cell death and differentiation   14(6):1095-1105 Full text @ Cell Death Differ.

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Gene: nkx2.5
Fish: WT, WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Anatomical Term: heart tube
Stage: Prim-5
PHENOTYPE:
Fish: WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Observed In: cardiac ventricle, eye, heart, heart primordium left side, heart primordium right side
Stage: Prim-5

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: cldna, egr2b, emx1, en2a, myod1 (all 8) expand
Fish: WT, WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Anatomical Terms: forebrain, hindbrain, midbrain hindbrain boundary, myotome, optic stalk (all 9) expand
Stage: Prim-5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Gene: rx1
Fish: WT, WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Anatomical Term: presumptive neural retina
Stage: Prim-5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Gene: rx1
Fish: WT, WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Anatomical Term: presumptive neural retina
Stage: Prim-5
PHENOTYPE:
Fish: WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Observed In: brain, CaP motoneuron, spinal cord
Stage: 20-25 somites

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes: otx2, pax6b, shha
Fish: WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Anatomical Terms: neural keel, neural plate, notochord, optic primordium
Stage: Bud

Fig. Text ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:
Fish: WT + MO1-igf1ra + MO1-igf1rb + MO2-igf1ra + MO2-igf1rb
Knockdown Reagents: MO1-igf1ra, MO1-igf1rb, MO2-igf1ra, MO2-igf1rb
Observed In: somite, whole organism
Stage Range: Prim-5 to Prim-15
Full text @ Cell Death Differ.