ZFIN ID: ZDB-ALT-170804-2
Genomic Feature: sm10
Synonyms: smu3 (1)
Affected Genomic Regions: mpl (1)
Type: Indel (1)
Protocol: embryos treated with TALEN1-mpl
Lab Of Origin: Yiyue ZHANG Lab
Location: Chr 6: 33978301 - 33978308 (GRCz11) (1) Details
Sequence:
Current Sources:
MUTATION DETAILS
DNA/cDNA Change: 48 bp inserted / 8 bp deleted in Exon 3 (1)
Transcript Consequence: Premature Stop (1)
Protein Consequence: Polypeptide Truncation (1)
FLANKING SEQUENCENo data available
NOTES
Comment Citation
the truncated Mpl protein lacking the two fibronectin type 3 domains and the  ... Lin et al., 2017
OTHER sm10 PAGESNo links to external sites
GENOTYPES
Zygosity Genotype (Background) Affected Genomic Regions Parental Zygosity
Homozygous mplsm10/sm10 (AB) mpl ♀+/- ♂+/-
Complex la2Tg ; mplsm10/sm10 mpl
sm9Tg ; mplsm10/sm10 mpl

CITATIONS  (1)