ZFIN Feature: hu745

ZFIN ID: ZDB-ALT-050914-2

ZFIN ID: ZDB-ALT-050914-2

Genomic Feature:	hu745
Synonyms:	mcr (1)
Affected Genomic Regions:	apc
Type:	Point Mutation (1)
Protocol:	ENU
Lab Of Origin:	Clevers Lab
Location:	Chr 10: 1887755 (GRCz11) (1) Details
Sequence:
Current Sources:

MUTATION DETAILS

DNA/cDNA Change:	C>T (1)
Transcript Consequence:	Premature Stop (1)
Protein Consequence:	Polypeptide Truncation : Gln>Stop at position 605 (1)

FLANKING SEQUENCE (GENOMIC)

AAGAAGAACAGCTCGAGGAACAAACTCCCAGCTACAGCATGAAATACACTGAGGATCATCATGTAGAGCAGCCTATTGATTACAGTTTGAAGTACTCGGAAGCTCCTTCCAAGAAGGGCATGTTTAGTCATTCAAAGACGTCTTCTGCACAGAGTTCTGCCAAAGAACATTTAAGCCAGGATAGTTCTTCTTCTGTGGCATCTTTAAAGAATCAGGGCAGGCAAAAGCAGCTCCACCCTTCATCTGCTCAAAGCAGATCCGGACCAACAAGAGCAGTTCAAAAGAACCCAACATGCAAGGCTCCCACAATAAATCAAGAAACTTTACAGACCTATTGTGTGGAAGATACTCCCATTTGTTTTTCACGTGGTAGCTCTTTATCGTCGTTGTCTTCAGAGGAGGATGAAATGGAGAGCTGTAAGCGTAATGTCAACTCGGCCAGTAACTACCCAACTTTACCTATATCAGAAAAACAATCCACTAATAATGTTGCAGCTGAC

C/T

AACGCACATCTGAGAGCCAATCATCAGTCCATTATGTTCGCGCCAAGCCTCCACGACATCATTTAGGACATGGTGATGGTTCCAGGCATCATAAAACGGTGGAGTTTTCATCAGGGGCTAAATCACCTTCTAAAAGTGGTGCCCAAACACCTAAAAGTCCCCCTGAGCATTATGTACAGGAGACTCCTCTAATGTTCAGCAGATGCACTTCAGTCAGCTCCCTTGACAGTTTTGAGAGTCATTCCATTGCCAGTTCTGTGCAGAGTGAGCCATGCAGTGGGATGGTCAGTGGCATCATCAGTCCGAGTGACTTACCTGATAGTCCTGGACAAACAATGCCTCCAAGTCGCAGCAAGACACCACCACCTCCACCTCCGCGGTCCACGTCAGTAAAACAGAAAGTTACAGTGCCACCCCACACTGAAAAACATGATTTGGCGCCAAGACATGCAGTTGTAAGTGCTGCCGTGCAAAAAGTGCAAGTTTTGCCAGATAATGAT

(1)

OTHER hu745 PAGES No links to external sites

GENOTYPES

Zygosity	Genotype (Background)	Affected Genomic Regions	Parental Zygosity
Homozygous	apc^hu745/hu745	apc	♀+/- ♂+/-
	apc^hu745/hu745	apc	Unknown
Heterozygous	apc^hu745/+	apc	♀+/- ♂+/-
	apc^hu745/+	apc	Unknown
Complex	apc^hu745/+; tcf7l2^zf55/+	apc, tcf7l2
	apc^hu745/+; tcf7l2^zf55/zf55	apc, tcf7l2
	apc^hu745/hu745; tcf7^{hu3238/hu3238}	apc, tcf7
	apc^hu745/hu745; tcf7l2^zf55/+	apc, tcf7l2
	apc^hu745/hu745; tcf7l2^zf55/zf55	apc, tcf7l2
	apc^hu745/hu745; rnf2^ibl31/ibl31	apc, rnf2
	apc^hu745/+; as3Tg	apc
	apc^hu745/+; jh1Tg	apc
	apc^hu745/+; s854Tg	apc
	apc^hu745/+; zf129Tg	apc
	apc^hu745/hu745; as3Tg	apc
	apc^hu745/hu745; ia5Tg	apc
	apc^hu745/hu745; s356tTg	apc
	apc^hu745/hu745; s854Tg	apc
	apc^hu745/hu745; y1Tg/y1Tg	apc
	apc^hu745/hu745; zf106Tg	apc
	apc^hu745/hu745; zf106Tg	apc
	apc^hu745; w25Tg	apc
	apc^hu745/hu745; rnf2^ibl30/ibl30	apc, rnf2

CITATIONS (44)