ZFIN ID: ZDB-ALT-050914-2
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Genomic Feature: hu745
Synonyms: mcr (1)
Affected Genomic Regions: apc
Type: Point Mutation (1)
Protocol: ENU 
Lab Of Origin: Clevers Lab
Location: Chr 10: 1887755 (GRCz11) (1) Details
Sequence:
Current Sources:
MUTATION DETAILS
DNA/cDNA Change: C>T (1)
Transcript Consequence: Premature Stop (1)
Protein Consequence: Polypeptide Truncation: Gln>Stop at position 605 (1)
FLANKING SEQUENCE (GENOMIC)
AAGAAGAACAGCTCGAGGAACAAACTCCCAGCTACAGCATGAAATACACTGAGGATCATCATGTAGAGCAGCCTATTGATTACAGTTTGAAGTACTCGGAAGCTCCTTCCAAGAAGGGCATGTTTAGTCATTCAAAGACGTCTTCTGCACAGAGTTCTGCCAAAGAACATTTAAGCCAGGATAGTTCTTCTTCTGTGGCATCTTTAAAGAATCAGGGCAGGCAAAAGCAGCTCCACCCTTCATCTGCTCAAAGCAGATCCGGACCAACAAGAGCAGTTCAAAAGAACCCAACATGCAAGGCTCCCACAATAAATCAAGAAACTTTACAGACCTATTGTGTGGAAGATACTCCCATTTGTTTTTCACGTGGTAGCTCTTTATCGTCGTTGTCTTCAGAGGAGGATGAAATGGAGAGCTGTAAGCGTAATGTCAACTCGGCCAGTAACTACCCAACTTTACCTATATCAGAAAAACAATCCACTAATAATGTTGCAGCTGAC
C/T
AACGCACATCTGAGAGCCAATCATCAGTCCATTATGTTCGCGCCAAGCCTCCACGACATCATTTAGGACATGGTGATGGTTCCAGGCATCATAAAACGGTGGAGTTTTCATCAGGGGCTAAATCACCTTCTAAAAGTGGTGCCCAAACACCTAAAAGTCCCCCTGAGCATTATGTACAGGAGACTCCTCTAATGTTCAGCAGATGCACTTCAGTCAGCTCCCTTGACAGTTTTGAGAGTCATTCCATTGCCAGTTCTGTGCAGAGTGAGCCATGCAGTGGGATGGTCAGTGGCATCATCAGTCCGAGTGACTTACCTGATAGTCCTGGACAAACAATGCCTCCAAGTCGCAGCAAGACACCACCACCTCCACCTCCGCGGTCCACGTCAGTAAAACAGAAAGTTACAGTGCCACCCCACACTGAAAAACATGATTTGGCGCCAAGACATGCAGTTGTAAGTGCTGCCGTGCAAAAAGTGCAAGTTTTGCCAGATAATGAT
(1)
OTHER hu745 PAGES No links to external sites
GENOTYPES
Zygosity Genotype (Background) Affected Genomic Regions Parental Zygosity
Homozygous apchu745/hu745 apc Unknown
apchu745/hu745 apc ♀+/- ♂+/-
Heterozygous apchu745/+ apc Unknown
apchu745/+ apc ♀+/- ♂+/-
Complex apchu745/+; tcf7l2zf55/+ apc, tcf7l2
apchu745/+; tcf7l2zf55/zf55 apc, tcf7l2
apchu745/hu745; tcf7hu3238/hu3238 apc, tcf7
apchu745/hu745; tcf7l2zf55/+ apc, tcf7l2
apchu745/hu745; tcf7l2zf55/zf55 apc, tcf7l2
apchu745/hu745; rnf2ibl31/ibl31 apc, rnf2
apchu745/+; as3Tg apc
apchu745/+; jh1Tg apc
apchu745/+; s854Tg apc
apchu745/+; zf129Tg apc
apchu745/hu745; as3Tg apc
apchu745/hu745; ia5Tg apc
apchu745/hu745; s356tTg apc
apchu745/hu745; s854Tg apc
apchu745/hu745; y1Tg/y1Tg apc
apchu745/hu745; zf106Tg apc
apchu745/hu745; zf106Tg apc
apchu745; w25Tg apc
apchu745/hu745; rnf2ibl30/ibl30 apc, rnf2
CITATIONS  (44)