ZFIN Feature: s327

ZFIN ID: ZDB-ALT-050617-10

ZFIN ID: ZDB-ALT-050617-10

Genomic Feature:	s327
Synonyms:	dark half (1)
Affected Genomic Regions:	gdf6a
Type:	Point Mutation (1)
Protocol:	adult males treated with ENU
Lab Of Origin:	Baier Lab
Location:	Chr 16: 39131377 (GRCz11) (1) Details
Sequence:
Current Sources:	Baier Lab

MUTATION DETAILS

DNA/cDNA Change:	C>A at position 167 (1)
Transcript Consequence:	Premature Stop (1)
Protein Consequence:	Polypeptide Truncation : Ser>Stop at position 55 (1)

FLANKING SEQUENCE (GENOMIC)

TTGTGGCCCAAGCAGGACGAGAGCTTACCAAATCTTTAGCACGTAAATAAACCACTAAGGAAAAAAGGGTAATTTAATTTCATAAGAAATATAATTAGGTGTCCTCTAACAATGATCTTTGTCGGTCGTGTTTTGTTTTAATTAGAGCAAAGAGATTTTAAGTACTTGCTTCACAAGTCTTTAAAGTTTGAGTTTAAGGCGTGAACACCATATTAAAATAATTATATAATTTAAGAATAACTTCTTTAAATAAAAAAGAAGAATAACTTTTAAGTGCAACAGTGCATGCTTCAAATAATGCATAAAACAGAATAAAGCAATACAAACCTTTTCCCTTGTCCACGAAACTCGTTATGGTGTTTGCAGACTTTGAAGAGCGGAAAAAGCTCGCATTGAGCCCCAGTTTCTCAGCGGCGGAGTAAGTCCTGTATATGGAGATCATGTAGTCATGAGGCACAACCGGGTCCTTAAAATCATCCCGACGACTCGCGCCCGGTGAT

G/T

ATGCTAAAATCTCTTTAAGAAATTTATGTGACCTTTGTCCATCAAACGCGCTCCTGGCACCCTTGCTCCTTTTCTGCGATATTAGCGCAGCTGACTGGCAACACGGTAAACTCCAGAGGAAAACGAAGAGCGCGTAAAAGGCGACTGCTCTCAAGGCATCCATGGTGTTACTATCCTCCAAAGAGTAAAGTGGAGCCGTGTCTCACAGTGAAGCCGGACTTTTTGGTTTGTGTTTGTTTGACGAGCGCGGACAGCGCGAGATCGGCGTGTTGCGTGTCTGAAGTGAAGTGCGCTGTAGACTCGAGAGCGCGAGGCTGCAGACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACTCACTCTCTCACATACACAAACTCACGTATACACACTCACTCGTGGCACGCCCACTGCACTCCTCAGACTATCCTGTATATATTGAACTTATCCACACTCTCTGCACAACTTTTCAGC

Comment	Citation
C-to-A transversion in position 167 of the ORF, leading to a truncated 54 amino ...	Gosse et al., 2009

OTHER s327 PAGES No links to external sites

GENOTYPES

Zygosity	Genotype (Background)	Affected Genomic Regions	Parental Zygosity
Homozygous	gdf6a^s327/s327	gdf6a	♀+/- ♂+/-
	gdf6a^s327/s327 (TL)	gdf6a	♀+/- ♂+/-
Heterozygous	gdf6a^s327/+	gdf6a	Unknown
	gdf6a^s327/+	gdf6a	♀+/- ♂+/-
Complex	gdf6a^s327/+ ; tbx2b^c144/c144	gdf6a, tbx2b
	gdf6a^s327/s327 ; tbx2b^c144/+	gdf6a, tbx2b
	tbx2b^c144/c144 ; gdf6a^s327/s327	gdf6a, tbx2b
	gdf6a^s327/s327 ; la116Tg	gdf6a
	gdf6a^s327/s327 ; s843Tg	gdf6a
	gdf6a^s327/s327; ci5Tg	gdf6a
	gdf6a^s327/s327; kj9Tg	gdf6a
	gdf6a^s327/s327; ml2Tg	gdf6a
	gdf6a^s327/s327; os10Tg	gdf6a
	gdf6a^s327/s327; s356tTg	gdf6a
	tp53^zdf1/zdf1 ; gdf6a^s327/s327 ; czt13Tg	gdf6a, tp53
	gdf6a^s327/s327 ; s843Tg ; sd2Tg	gdf6a
	gdf6a^s327/s327; ci5Tg; ua1013Tg	gdf6a
	gdf6a^s327/s327; kj9Tg; ua3011Tg	gdf6a
	ua3011Tg ; gdf6a^s327/s327 ; ua3113Tg ; kj9Tg	gdf6a
Unknown	gdf6a^s327	gdf6a	Unknown

CITATIONS (22)