ZFIN ID: ZDB-EXP-190726-3
Experiment Conditions Description: light ablation: pronephros, chemical treatment by environment: 2-deoxy-D-glucose
light ablation: pronephros
Name: light ablation
Synonyms:
Definition: Experimental condition which uses focused light to ablate an anatomical structure or cell.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000170]
Name: pronephros
Synonyms: embryonic kidney, pronephric nephron
Definition: The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.
Ontology: Anatomy Ontology [ZFA:0000151]
chemical treatment by environment: 2-deoxy-D-glucose
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: 2-deoxy-D-glucose
Synonyms: 2-deoxy-D-arabino-hexose, 2-Deoxy-D-glucose, 2-Deoxy-D-mannose, D-2dGlc, D-arabino-2-Deoxyhexose, Deoxyglucose
Definition: A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Ontology: ChEBI [CHEBI:15866]  ( EBI )
Publication: Yakulov et al., 2018