ZFIN ID: ZDB-EXP-190625-13
Experiment Conditions Description: transection: caudal fin, chemical treatment by injection: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, chemical treatment by environment: prostaglandin E2
transection: caudal fin
Name: transection
Synonyms:
Definition: Cutting transversly of an organ or tissue. Type of cutting often used to divide the spinal cord to investigate neural regeneration in zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000181]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
chemical treatment by injection: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
Synonyms: 15-lipoxygenase inhibitor, 15-lipoxygenase inhibitors, 15-LOX inhibitor, 15-LOX inhibitors, arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor, arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors, arachidonate 15-lipoxygenase inhibitor, arachidonate 15-lipoxygenase inhibitors, arachidonate:oxygen 15-oxidoreductase inhibitor, arachidonate:oxygen 15-oxidoreductase inhibitors, EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors, EC 1.13.11.33 inhibitor, EC 1.13.11.33 inhibitors, linoleic acid omega(6)-lipoxygenase inhibitor, linoleic acid omega(6)-lipoxygenase inhibitors, omega(6) lipoxygenase inhibitor, omega(6) lipoxygenase inhibitors
Definition: A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33).
Ontology: ChEBI [CHEBI:64996]  ( EBI )
chemical treatment by environment: prostaglandin E2
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: prostaglandin E2
Synonyms: (15S)-prostaglandin E2, (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate, (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid, (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid, Cervidil, Cerviprime, Cerviprost, Dinoproston, dinoprostona, dinoprostone, dinoprostonum, Enzaprost E, Glandin-E2, Minprositin E2, Minprostin E2, PGE2, Prepidil, Propess, Prostaglandin E2, Prostarmon E, Prostenone, Prostin, Prostin E2, U 12062, U-12,062, U-12062
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Ontology: ChEBI [CHEBI:15551]  ( EBI )
Publication: Loynes et al., 2018