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ZIRC
ZFIN ID: ZDB-EXP-190530-4
Experiment Conditions Description: chemical treatment by injection: BCI-215, resection: cardiac ventricle
chemical treatment by injection: BCI-215
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: BCI-215
Synonyms: (2E)-2-benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
Definition: An aromatic ketone that is 2,3-dihydro-1H-inden-1-one which is substituted at positions 2, 3, and 5 by (E)-benzylidene, cyclohexylamino, and bromine, respectively. A hyperactivator of fibroblast growth factor signaling in transgenic zebrafish that is devoid of developmental toxicity and restores defective MAPK activity caused by overexpression of DUSP1 and DUSP6 in mammalian cells.
Ontology: Chebi [CHEBI:143128]
resection: cardiac ventricle
Name: resection
Synonyms:
Definition: Surgical manipulation in which a particular organ, appendage, or part of the zebrafish is removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000171]
Name: cardiac ventricle
Synonyms: ventricle
Definition: Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart.
Ontology: Anatomy Ontology [ZFA:0000009]
Publication: Missinato et al., 2018