ZFIN ID: ZDB-EXP-190207-7
Experiment Conditions Description: perforation: retina, chemical treatment: DAPT
perforation: retina
Name: perforation
Synonyms:
Definition: Experimental condition in which a hole or break in the membranes of an organ or structure of the body is created.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000178]
Name: retina
Synonyms: retinas
Definition: Multi-tissue structure that contains the retinal neural layer and the retinal pigmented epithelium, and develops from the optic cup.
Ontology: Anatomy Ontology [ZFA:0000152]
chemical treatment: DAPT
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: DAPT
Synonyms: Dapt, gamma-secretase inhibitor IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
Definition: A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. A gamma-secretase inhibitor.
Ontology: Chebi [CHEBI:86193]
Publication: Kaur et al., 2018