ZFIN ID: ZDB-EXP-180111-4
Experiment Conditions Description: light ablation: anterior lateral line ganglion, light ablation: statoacoustic (VIII) ganglion, chemical treatment by environment: leflunomide
light ablation: anterior lateral line ganglion
Name: light ablation
Synonyms:
Definition: Experimental condition which uses focused light to ablate an anatomical structure or cell.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000170]
Name: anterior lateral line ganglion
Synonyms: anterior lateral line ganglia
Definition: The anterior lateral line ganglia develops from cranial ectodermal placodes and contain sensory neurons that innervate the anterior lateral line system.
Ontology: Anatomy Ontology [ZFA:0001391]
light ablation: statoacoustic (VIII) ganglion
Name: light ablation
Synonyms:
Definition: Experimental condition which uses focused light to ablate an anatomical structure or cell.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000170]
Name: statoacoustic (VIII) ganglion
Synonyms: auditory ganglion, gVIII, octaval ganglion, sag, statoacoustic ganglia
Definition: The sensory ganglion of the ear. (See Anatomical Atlas entry for statoacoustic ganglion by T. Whitfield.)
Ontology: Anatomy Ontology [ZFA:0000588]
chemical treatment by environment: leflunomide
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: leflunomide
Synonyms: 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide, 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide, alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide, Arava, leflunomida, leflunomide, leflunomidum
Definition: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Ontology: Chebi [CHEBI:6402]
Publication: Zecca et al., 2015