| ZFIN ID: ZDB-EXP-170323-2 |
Experiment Conditions Description: chemical treatment by environment: Y-27632, surgical manipulation: scale
| chemical treatment by environment: Y-27632 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Y-27632 |
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| Synonyms: | (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide, trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide, Y 27632 |
| Definition: | A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme. |
| Ontology: | ChEBI [CHEBI:75393] ( EBI ) |
| surgical manipulation: scale |
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| Name: | surgical manipulation |
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| Synonyms: | |
| Definition: | Experimental condition that involves manual or instrumental techniques to alter anatomical structures. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000176] |
| Name: | scale |
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| Synonyms: | scales |
| Definition: | Dermal bone that is thin, flexible, and platelike, and that develops in overlapping skinfolds that cover the body and often the head of fish and the bases of the fins. |
| Ontology: | Anatomy Ontology [ZFA:0000277] |
| Publication: | Richardson et al., 2016 |
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